Loading...

APC/Cyanine7 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_APCCy7_021808
C57BL/6 mouse bone marrow stained with M1/70 APC/Cyanine7
  • M1slash70_APCCy7_021808
    C57BL/6 mouse bone marrow stained with M1/70 APC/Cyanine7
Compare all formats See APC/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
101225 25 µg £65
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101226 100 µg £148
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Additional Product Notes
BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Casellas Roman HL, et al. 2020. Leuk Res. 94:106372. PubMed
  2. Yokozeki Y, et al. 2021. Biomed Res Int. 2021:7988320. PubMed
  3. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  4. Brown A, et al. 2012. Arterioscler Thromb Vasc Biol. 32:2122. PubMed
  5. Dixit N, et al. 2012. J Immunol. 189:5954. PubMed
  6. Wangdi T, et al. 2014. PLoS Pathog. 10:1004306. PubMed
  7. Chung Y, et al. 2014. J Vis Exp. 89: 51660. PubMed
  8. Daemen S, et al. 2021. Cell Reports. 34(2):108626. PubMed
  9. Sweet R, et al. 2017. J Immunol. 10.4049/jimmunol.1600861. PubMed
  10. Filipello F et al. 2018. Immunity. 48(5):979-991 . PubMed
  11. Mathur R, et al. 2019. Mucosal Immunol. 12:612. PubMed
  12. Miragaia RJ, et al. 2019. Immunity. 50:493. PubMed
  13. Yang N, et al. 2022. NPJ Vaccines. 7:120. PubMed
  14. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  15. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  16. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  17. Nguyen NDNT, et al. 2020. NPJ Vaccines. 5:7. PubMed
  18. Larson-Casey JL, et al. 2021. FASEB J. 35:e21675. PubMed
  19. Savio LEB, et al. 2020. J Cell Sci. 133:jcs237560. PubMed
  20. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  21. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  22. Zhou J, et al. 2019. Immunity. 50:403. PubMed
  23. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
  24. Cho SM et al. 2018. Journal of neurochemistry. 148(5):625-638 . PubMed
  25. Sakamoto T, et al. 2021. Commun Biol. 4:1165. PubMed
  26. Chen S, et al. 2022. Cancer Discov. :. PubMed
  27. Gattas MJ, et al. 2021. International Journal of Molecular Sciences. 22(10):. PubMed
  28. Yilmaz B, et al. 2021. Cell Host Microbe. 29(4):650-663.e9. PubMed
  29. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  30. Giambra V et al. 2018. Cell stem cell. 23(5):714-726 . PubMed
  31. Lino AC et al. 2018. Immunity. 49(1):120-133 . PubMed
  32. Zhang K, et al. 2018. PLoS Pathog. 14:e1006925. PubMed
  33. Delás MJ, et al. 2019. Cell Rep. 27:719. PubMed
  34. Kashyap AS, et al. 2019. Cell Rep. 28:3367. PubMed
  35. Yang M, et al. 2020. Cell Prolif. 53:e12784. PubMed
  36. Achmus L, et al. 2020. Front Neurol. 11:577971. PubMed
  37. Nagatake T, et al. 2022. Mucosal Immunol. 15:289. PubMed
  38. Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
  39. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  40. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  41. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  42. Clement M, et al. 2016. PLoS Pathog. 12:e1006050. PubMed
  43. Billroth-MacLurg, AC, et al. 2016. J Immunol. 197:2208-2218. PubMed
  44. Eastman A, et al. 2016. J Immunol . 194: 5999-6010. PubMed
  45. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  46. Spees A, et al. 2013. MBio. 2:430. PubMed
  47. Harel M, et al. 2020. Cell. 179(1):236-250.e18.. PubMed
  48. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  49. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  50. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  51. Kleinholz CL, et al. 2021. Sci Rep. 11:15071. PubMed
  52. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  53. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  54. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  55. Yang F, et al. 2020. Cancer Res. 80:3677. PubMed
  56. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  57. Getts D, et al. 2014. Sci Transl Med. 15:219. PubMed
  58. Tanaka Y, et al. 2015. PLoS One. 10: 0138621. PubMed
  59. Palamides P, et al. 2016. Dis Model Mech. 9: 985 - 997. PubMed
  60. Wang H, et al. 2019. Immunotherapy. 11:101. PubMed
  61. Davis FM, et al. 2019. Arterioscler Thromb Vasc Biol. 39:2353. PubMed
  62. Di Gioia M, et al. 2020. Nat Immunol. 21:42. PubMed
  63. Bhattacherjee A, et al. 2021. Mol Neurodegener. 16:19. PubMed
  64. Wang C, et al. 2021. Cell Rep. 37:110021. PubMed
  65. Stahlhut M, et al. 2021. Sci Rep. 11:5294. PubMed
  66. Gordon RA, et al. 2020. PLoS One. 15:e0226396. PubMed
  67. Diao N, et al. 2016. Sci Rep. 6:34672. PubMed
  68. Krueger K, et al. 2014. Stem Cell Reports. 9:1147. PubMed
  69. Saika A, et al. 2020. FASEB Bioadv. 2:59. PubMed
  70. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  71. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  72. Mariani SA, et al. 2019. Immunity. 50:1439. PubMed
  73. Goggi JL, et al. 2020. Mol Imaging Biol. 22:1392. PubMed
  74. Zhang X, et al. 2022. Theranostics. 12:1621. PubMed
  75. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  76. Wu X, et al. 2021. Elife. 10:. PubMed
  77. Wang B, et al. 2022. Nat Commun. 13:3821. PubMed
  78. Jiang N, et al. 2022. Nat Commun. 13:1511. PubMed
  79. Glass A, et al. 2013. J Immunol. 190:4830. PubMed
  80. Kurkewich J, et al. 2016. PLoS One. 11: 0161468. PubMed
  81. Jeljeli M, et al. 2020. Cell Rep. 33:108325. PubMed
  82. Hagan AS, et al. 2020. Development. 147:00:00. PubMed
  83. Wei SC, et al. 2020. Cancer Discov. . PubMed
  84. Dos Santos Dias L, et al. 2021. PLoS Pathog. e1009324:17. PubMed
  85. Kunimoto H, et al. 2018. Cancer Cell. 33:44. PubMed
  86. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  87. Parlet CP, et al. 2019. Cell Rep. 27:187. PubMed
  88. Zhang S, et al. 2019. Cell Metab. 29:443. PubMed
  89. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  90. García-Bonilla M, et al. 2020. Stem Cell Res Ther. 11:121. PubMed
  91. Yang L, et al. 2021. Cell Death Differ. 28:2616. PubMed
  92. McAlpine CS, et al. 2021. Nature. 595:701. PubMed
  93. Naler LB, et al. 2022. Commun Biol. 5:102. PubMed
  94. Kornstädt L, et al. 2021. Front Immunol. 11:607048. PubMed
  95. Kirschbaum K, et al. 2016. Proc Natl Acad Sci U S A. 113: 13227 - 13232. PubMed
  96. Ano Y, et al. 2017. J Biol Chem. 292:3720. PubMed
  97. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  98. Kleppe M et al. 2018. Cancer cell. 33(1):29-43 . PubMed
  99. Kobayashi M, et al. 2020. Bio Protoc. 10:e3601. PubMed
  100. Geng S, et al. 2021. JCI Insight. 6:. PubMed
  101. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  102. Pan Y, et al. 2022. J Clin Invest. 132:. PubMed
  103. Zhu Y, et al. 2022. Clin Transl Med. 12:e887. PubMed
  104. Feng S, et al. 2022. Front Immunol. 13:990522. PubMed
  105. Hutter K, et al. 2020. FEBS J. . PubMed
  106. Zhao J, et al. 2018. Stem Cell Reports. 10:180. PubMed
  107. Mamedov MR, et al. 2018. Immunity. 48:350. PubMed
  108. Codina A, et al. 2019. Cell Syst. 8:136. PubMed
  109. Hulsmans M et al. 2017. Cell. 169(3):510-522 . PubMed
  110. Yu X, et al. 2020. Nat Commun. 0.641666667. PubMed
  111. Vicencio JM, et al. 2022. Cell Death Dis. 13:274. PubMed
  112. Pradhan K, et al. 2021. Front Immunol. 12:778830. PubMed
  113. Panea C, et al. 2021. Commun Biol. 4:913. PubMed
  114. Witkowski MT, et al. 2020. Cancer Cell. 37:867. PubMed
  115. Hu Y, et al. 2021. Bioact Mater. 2905:6. PubMed
  116. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  117. McFarland AP, et al. 2021. Immunity. 54(6):1320-1337.e4. PubMed
  118. Kenswil KJG, et al. 2021. Cell Stem Cell. 28(4):653-670.e11. PubMed
  119. Zhang C, et al. 2020. Cell Rep. 32:108206. PubMed
  120. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  121. Niknam S, et al. 2018. Clin Cancer Res. 24:5735. PubMed
  122. Pfefferlé M, et al. 2021. Front Immunol. 12:680855. PubMed
  123. Ma S, et al. 2022. Cell Rep. 38:110520. PubMed
  124. Guldner IH, et al. 2020. Cell. 183(5):1234-1248.e25. PubMed
  125. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  126. Martínez‐López M et al. 2019. Immunity. 50(2):446-461 . PubMed
  127. Casulli J, et al. 2019. Nat Commun. 10:2121. PubMed
  128. Xiong X et al. 2019. Mol Cell. 75(3):644-660 . PubMed
  129. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  130. Pietronigro E, et al. 2019. Sci Rep. 9:12055. PubMed
  131. Yang S, et al. 2022. J Exp Med. 219:. PubMed
  132. Cheresh P, et al. 2020. Int J Mol Sci. 21:. PubMed
  133. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  134. Larson-Casey JL, et al. 2021. J Biol Chem. :100810. PubMed
  135. San Gil R, et al. 2021. Cells. 10: . PubMed
  136. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  137. Yi W, et al. 2021. Cell Reports. 34(13):108922. PubMed
  138. Murakami K, et al. 2021. Cell Reports. 34(1):108579. PubMed
  139. LM S, et al. 2016. Cell Rep. 16(12): 3286-96. PubMed
  140. Lammers K, et al. 2015. PLoS One. 10: 0138338. PubMed
  141. Ermert D, et al. 2016. PLoS Pathog. 11: 1005043. PubMed
  142. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  143. Crane A, et al. 2018. Alzheimers Dement. 14:243. PubMed
  144. Chen Z, et al. 2019. J Exp Med. 216:152. PubMed
  145. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  146. Landon J Edgar et al. 2018. Cell chemical biology. 26(1):131-136 . PubMed
  147. Liu S, et al. 2018. Front Immunol. 29:208. PubMed
  148. Daemen S, et al. 2021. STAR Protoc. 2:100511. PubMed
  149. Shibad V, et al. 2021. Front Immunol. 12:722451. PubMed
  150. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  151. Robles-Oteiza C, et al. 2021. Dis Model Mech. 14:. PubMed
  152. Gómez LA, et al. 2020. Front Microbiol. 11:1586. PubMed
  153. Xu X, et al. 2022. EMBO Rep. 23:e53509. PubMed
  154. Yabas M, et al. 2016. PLoS One. 11: 0146774. PubMed
  155. Wu X, et al. 2016. Sci Rep. 6:18685. PubMed
  156. Savio LEB, et al. 2020. J Cell Sci. 133:00:00. PubMed
  157. Li CJ, et al. 2018. J Clin Invest. 128:5251. PubMed
  158. Goldstein JM et al. 2019. Cell reports. 27(4):1254-1264 . PubMed
  159. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  160. Carestia A, et al. 2019. Cell Rep. 28:896. PubMed
  161. Zhang CR, et al. 2022. Blood Cancer Discov. 3:220. PubMed
  162. Anderson-Baucum E, et al. 2021. Cell Metab. 33:1883. PubMed
  163. Mendelsohn AC, et al. 2020. Am J Physiol Cell Physiol. 319:C997. PubMed
  164. King R, et al. 2021. Sci Adv. 7:eabj5293. PubMed
  165. Murdock BJ, et al. 2021. JCI Insight. 6:. PubMed
  166. Taya M, et al. 2020. Endocr Relat Cancer. 27:261. PubMed
  167. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  168. Larson-Casey JL, et al. 2020. PLoS One. 15:e0241323. PubMed
  169. Kim M, et al. 2018. Immunity. 49:151. PubMed
  170. Nowak W, et al. 2020. EBioMedicine. 50:290-305.. PubMed
  171. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  172. Qiao S, et al. 2019. J Neuroinflammation. 16:4. PubMed
  173. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  174. Sia J, et al. 2017. PLoS Pathog.. 10.1371/journal.ppat.1006530. PubMed
  175. Bhatt D, et al. 2021. J Exp Med. 218:. PubMed
  176. Karolin A, et al. 2022. Front Pharmacol. 12:789080. PubMed
  177. Gao Z, et al. 2022. J Inflamm Res. 15:3337. PubMed
  178. Jing Y, et al. 2021. Front Immunol. 12:651860. PubMed
  179. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  180. Celik H, et al. 2018. Cancer Cell. 34:741. PubMed
  181. Yin S et al. 2019. Cancer cell. 35(2):283-296 . PubMed
  182. Zhao Y, et al. 2020. Immunity. 51(6):1059-1073.e9.. PubMed
  183. Soncin I, et al. 2018. Nat Commun. 9:582. PubMed
  184. Tulyeu J, et al. 2021. Curr Protoc. 1:e283. PubMed
  185. Zhang W, et al. 2021. Front Immunol. 12:768435. PubMed
  186. Wang Z, et al. 2020. J Cell Mol Med. . PubMed
  187. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  188. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  189. Flores AM, et al. 2020. Nat Nanotechnol. 0.731944444. PubMed
  190. McKenzie MD, et al. 2019. Cell Stem Cell. 25:258. PubMed
  191. Pradhan K, et al. 2021. J Immunol. 206:2980. PubMed
  192. Smith KJ, et al. 2022. PLoS Biol. 20:e3001554. PubMed
  193. Zhang L, et al. 2021. Front Mol Biosci. 8:647647. PubMed
  194. Liu Q, et al. 2021. Adv Mater. 33:e2102852. PubMed
  195. Lin R, et al. 2022. Cell Death Dis. 13:345. PubMed
  196. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  197. Hoyer FF, et al. 2020. Immunity. 51(5):899-914.e7.. PubMed
  198. Fite BZ, et al. 2021. Sci Rep. 11:927. PubMed
  199. Liu X, et al. 2021. Adv Sci (Weinh). 8:e2100233. PubMed
  200. Chavkin NW, et al. 2021. J Am Heart Assoc. 10:e019904. PubMed
  201. Luo X, et al. 2021. Neuron. 109(17):2691-2706.e5. PubMed
  202. Siolas D, et al. 2021. Cell Reports. 36(8):109578. PubMed
  203. Aryal B, et al. 2016. Nat Commun. 7:12313. PubMed
  204. Lee MC, et al. 2017. J Immunol. 198:3565. PubMed
  205. Säwen P et al. 2018. eLife. 7 pii: e41258. PubMed
  206. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  207. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  208. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  209. Park HJ, et al. 2021. Int J Mol Sci. 22:. PubMed
  210. Wang X, et al. 2021. Sci Transl Med. 13:. PubMed
  211. Lau A, et al. 2022. Sci Adv. 8:eabm0142. PubMed
  212. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  213. Larson–Casey JL, et al. 2019. J Clin Invest. 129:4962. PubMed
  214. Patterson DG, et al. 2021. J Immunol. 207:1798. PubMed
  215. Lippeveld M, et al. 2020. Cytometry A. 97:308. PubMed
  216. Avgustinova A, et al. 2021. Cell Stem Cell. . PubMed
  217. Cortez MA, et al. 2020. Nat Commun. 3.819444444. PubMed
  218. C Khouili S, et al. 2020. Cell Rep. 33:108468. PubMed
  219. Geng S, et al. 2016. Nat Commun. 7:13436. PubMed
  220. Denk F, et al. 2016. Cell Rep. 15: 1771-1781. PubMed
  221. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  222. Ge Y, et al. 2020. Mucosal Immunol. 13:34. PubMed
  223. Cabal-Hierro L, et al. 2020. Nat Commun. 11:1406. PubMed
  224. Syed I et al. 2018. Cell metabolism. 27(2):419-427 . PubMed
RRID
AB_830641 (BioLegend Cat. No. 101225)
AB_830642 (BioLegend Cat. No. 101226)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • APC anti-mouse/human CD11b

  • Biotin anti-mouse/human CD11b

  • FITC anti-mouse/human CD11b

  • PE anti-mouse/human CD11b

  • PE/Cyanine5 anti-mouse/human CD11b

  • Purified anti-mouse/human CD11b

  • PE/Cyanine7 anti-mouse/human CD11b

  • Alexa Fluor® 488 anti-mouse/human CD11b

  • Alexa Fluor® 647 anti-mouse/human CD11b

  • Alexa Fluor® 700 anti-mouse/human CD11b

  • Pacific Blue™ anti-mouse/human CD11b

  • APC/Cyanine7 anti-mouse/human CD11b

  • PerCP/Cyanine5.5 anti-mouse/human CD11b

  • PerCP anti-mouse/human CD11b

  • Brilliant Violet 421™ anti-mouse/human CD11b

  • Brilliant Violet 570™ anti-mouse/human CD11b

  • Brilliant Violet 605™ anti-mouse/human CD11b

  • Brilliant Violet 650™ anti-mouse/human CD11b

  • Brilliant Violet 711™ anti-mouse/human CD11b

  • Brilliant Violet 785™ anti-mouse/human CD11b

  • Brilliant Violet 510™ anti-mouse/human CD11b

  • Ultra-LEAF™ Purified anti-mouse/human CD11b

  • Purified anti-mouse/human CD11b (Maxpar® Ready)

  • Alexa Fluor® 594 anti-mouse/human CD11b

  • PE/Dazzle™ 594 anti-mouse/human CD11b

  • APC/Fire™ 750 anti-mouse/human CD11b

  • TotalSeq™-A0014 anti-mouse/human CD11b

  • Brilliant Violet 750™ anti-mouse/human CD11b

  • TotalSeq™-B0014 anti-mouse/human CD11b

  • TotalSeq™-C0014 anti-mouse/human CD11b

  • Spark NIR™ 685 anti-mouse/human CD11b

  • PE/Fire™ 640 anti-mouse/human CD11b

  • Spark YG™ 593 anti-mouse/human CD11b

  • Spark YG™ 570 anti-mouse/human CD11b

  • PE/Fire™ 810 anti-mouse/human CD11b

  • APC/Fire™ 810 anti-mouse/human CD11b Antibody

  • Spark Blue™ 550 anti-mouse/human CD11b

  • Spark UV™ 387 anti-mouse/human CD11b
ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account