- Michel-19 (See other available formats)
- Regulatory Status
- Other Names
- Rat IgG1, κ
- Ave. Rating
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- Product Citations
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CD83 is a 45 kD type I transmembrane protein. It belongs to immunoglobulin superfamily and is expressed on mature dendritic cells and activated lymphocytes. CD83 is involved in the regulation of T cell development and immune response. Soluble form CD83 has been reported to inhibit dendritic cell maturation and dendritic cell-mediated T cell proliferation. Murine CD83 ligand has been found on B cells.Product Details
- Antibody Type
- Host Species
- Recombinant mouse CD83 protein
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for relevant formats of this clone) include: immunohistochemistry of acetone - fixed frozen sections4.
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
(PubMed link indicates BioLegend citation)
- Cramer SO, et al. 2000. Int. Immunol. 12:1347.
- Fujimoto Y, et al. 2002. Cell 108:755.
- Mott KR, et al. 2009. Virol J. 6:56. (FC) PubMed
- Roland Cl, et al. 2009. Mol Cancer Res. 8:1761. (IHC) PubMed
- Masuda Y, et al. 2010. Cancer Immunol Immunother. [Epub ahead of print] (FC) PubMed
- Tze LE, et al. 2011. J Exp Med. PubMed
- del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
- Product Citations
AB_2566123 (BioLegend Cat. No. 121517)
AB_2566124 (BioLegend Cat. No. 121518)
- Type I transmembrane protein, Ig superfamily, 45kD
Mature dendritic cells, activated lymphocytes
- Regulate T cell development and immune response, soluble form CD83 inhibit dendritic cell maturation
- CD83 ligand
- Cell Type
- Dendritic cells, Lymphocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
1. Lechmann M, et al. 2005. Biochem. Biophys. Res. Commun. 329:132.
2. Kotxor N, et al. 2004. Immunobiology 209:129.
3. Leon F, et al. 2004. J. Immunol. 173:2995.
4. Cramer SO, et al. 2000. Int. Immunol. 12:1347.
5. Fujimoto Y, et al. 2002. Cell 108:755.
- Gene ID
- 12522 View all products for this Gene ID
- View information about CD83 on UniProt.org
|Purified anti-mouse CD83||Michel-19||FC|
|Biotin anti-mouse CD83||Michel-19||FC|
|FITC anti-mouse CD83||Michel-19||FC|
|PE anti-mouse CD83||Michel-19||FC|
|APC anti-mouse CD83||Michel-19||FC|
|Alexa Fluor® 488 anti-mouse CD83||Michel-19||FC|
|Alexa Fluor® 647 anti-mouse CD83||Michel-19||FC|
|Brilliant Violet 650™ anti-mouse CD83||Michel-19||FC|
|PE/Cyanine7 anti-mouse CD83||Michel-19||FC|
|TotalSeq™-A0562 anti-mouse CD83||Michel-19||PG|
|TotalSeq™-C0562 anti-mouse CD83||Michel-19||PG|
|TotalSeq™-B0562 anti-mouse CD83||Michel-19||PG|
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-mouse CD83
Biotin anti-mouse CD83
FITC anti-mouse CD83
PE anti-mouse CD83
APC anti-mouse CD83
Alexa Fluor® 488 anti-mouse CD83
Alexa Fluor® 647 anti-mouse CD83
Brilliant Violet 650™ anti-mouse CD83
PE/Cyanine7 anti-mouse CD83
TotalSeq™-A0562 anti-mouse CD83
TotalSeq™-C0562 anti-mouse CD83
TotalSeq™-B0562 anti-mouse CD83