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PE/Cyanine7 anti-mouse CD11c Antibody

Pricing & Availability
Clone
N418 (See other available formats)
Regulatory Status
RUO
Other Names
αX integrin, integrin αX chain, CR4, p150, ITGAX
Isotype
Armenian Hamster IgG
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Product Citations
publications
N418_A_PEslashCy7_Pos_071006
C57BL/6 mouse splenocytes stained with APC anti-mouse I-A/I-E (clone M5/114.15.2) and PE/Cyanine7 N418 (top) or PE/Cyanine7 Armenian hamster IgG isotype control (bottom)
  • N418_A_PEslashCy7_Pos_071006
    C57BL/6 mouse splenocytes stained with APC anti-mouse I-A/I-E (clone M5/114.15.2) and PE/Cyanine7 N418 (top) or PE/Cyanine7 Armenian hamster IgG isotype control (bottom)
  • N418_B_PEslashCy7_Neg_071006
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
117317 25 µg $94
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117318 100 µg $231
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Description

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse spleen dendritic cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for other applications.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9 (Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.

Additional Product Notes

View more applications data for this product in our Scientific Poster Library.

 


BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.

 

Application References

(PubMed link indicates BioLegend citation)
  1. Granucci F, et al. 1997. J. Immunol. 159:1794.
  2. Stokes RW, et al. 1998. J. Immunol. 160:5514.
  3. Metlay JP, et al. 1990. J. Exp. Med. 171:1753. (IHC, IP)
  4. Ma XT, et al. 2006. Cancer Research 66:1169.
  5. Chin RK, et al. 2006. J. Immunol. 177:290. (IF)
  6. Cervantes-Barragan L, et al. 2007. Blood 109:1131. (FC) PubMed
  7. Turnquist HR, et al. 2007. J. Immunol. 178:7018. (FC) PubMed
  8. Benson MJ, et al. 2007. J. Exp. Med. doi:10.1084/jem.20070719. (FC) PubMed
  9. You Y, et al. 2009. J. Immunol. 182:7343. (IF) PubMed
  10. Roland CL, et al. 2009. Mol. Cancer Res. 8:1761. (IHC, FC) PubMed
  11. Wikstrom M, et al.2006. J. Immunol. 177:913. PubMed
  12. Pericolini E, et al. 2008. J. Leukocyte Biol. 83:1286. PubMed
  13. Randall LM, et al. 2008. Infect. Immun.76:3312. PubMed
  14. Fahlen-Yrild L, et al. 2009. J. Immunol. 183:5032. PubMed
  15. Osterholzer JJ, et al. 2009. J. Immunol. 183:8044. PubMed
  16. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed
  17. Eisenach PA, et al. 2010. J Cell Sci. 123:4182. PubMed
  18. Leppin K, et al. 2014. Invest. Ophthalmol. Vis. Sci. 55:3603. PubMed
  19. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  20. Gibbins JD, et al. 2014. Blood. 124:2953. PubMed
  21. White CE, et al. 2015. J Immunol. 194:697. PubMed
  22. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  23. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  24. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Komuczki J, et al. 2019. Immunity. 50:1289. PubMed
  2. Wang X, et al. 2019. Cell Res. 29:787. PubMed
  3. Kimura S, et al. 2020. Nat Commun. 0.620833333. PubMed
  4. Al–Rashed F, et al. 2020. Sci Rep. 10:16802. PubMed
  5. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  6. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  7. Jiang Z, et al. 2021. J Clin Invest. 131: . PubMed
  8. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  9. Friess MC, et al. 2022. Cell Rep. 38:110334. PubMed
  10. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  11. Furrer R, et al. 2021. Sci Adv. 7:eabi4852. PubMed
  12. Fu R, et al. 2020. Sci Rep. 10:1455. PubMed
  13. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
  14. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  15. Lyons J, et al. 2018. PLoS Biol. 16:e2002417. PubMed
  16. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
  17. Furuta Y, et al. 2017. PLoS One. 12(2):e0172509. PubMed
  18. Kolawole A, et al. 2015. J Virol. 90: 1499-1506. PubMed
  19. Kawano H, et al. 2016. Int Immunol. 28: 489 - 501. PubMed
  20. Shin J, et al. 2016. Sci Rep. 6:23426. PubMed
  21. van Vloten JP, et al. 2022. J Immunother Cancer. 10:. PubMed
  22. Ferrere G, et al. 2021. JCI Insight. 6:. PubMed
  23. Jong RM, et al. 2022. J Immunol. 208:407. PubMed
  24. Ercoli G, et al. 2021. Front Immunol. 11:611661. PubMed
  25. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  26. Thwe PM et al. 2017. Cell metabolism. 26(3):558-567 . PubMed
  27. Kurelac I, et al. 2019. Nat Commun. 10:903. PubMed
  28. Quatrini L, et al. 2018. Nat Immunol. 19:954. PubMed
  29. Suzuki T, et al. 2014. J Dermatol Sci. 74:116. PubMed
  30. Clark K, et al. 2015. J Autoimmun. Available online 21 August 2015. PubMed
  31. Ndoja A, et al. 2020. Cell. 182(5):1156-1169.e12. PubMed
  32. Dong L, et al. 2021. Cancer Cell. . PubMed
  33. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  34. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  35. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  36. Boldison J, et al. 2020. Cell Mol Immunol. 17:843. PubMed
  37. Liang S, et al. 2022. Acta Pharm Sin B. 12:2494. PubMed
  38. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  39. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  40. Pack AD, et al. 2021. Cell Reports. 36:109586. PubMed
  41. Hearnden R, et al. 2021. STAR Protocols. 2(2):100422. PubMed
  42. Yousif AS, et al. 2020. Immunity. 54(2):235-246.e5. PubMed
  43. Ku M, et al. 2016. Mol Cancer Ther. 15: 1975 - 1987. PubMed
  44. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  45. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  46. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  47. Yu X, et al. 2021. Nature. 594:560. PubMed
  48. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  49. Morgado P, et al. 2014. Infect Immun . 82:4047. PubMed
  50. Ohtsuki T, et al. 2016. J Virol. 90: 300 - 307. PubMed
  51. Bazett M, Haston M 2016. Sci Rep. 6:19189. PubMed
  52. Rao S, et al. 2017. Cell. 168(3):503-516.e12. PubMed
  53. Si Y, et al. 2020. Sci Adv. 6:eaba0995. PubMed
  54. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  55. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  56. Jtte BB, et al. 2021. iScience. 24(8):102833. PubMed
  57. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  58. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  59. Papafragkos I, et al. 2022. Front Immunol. 13:889075. PubMed
  60. van Dierendonck XAMH, et al. 2020. Cell Reports. 30(6):1811-1822. PubMed
  61. Nguyen CM, et al. 2019. Diabetes. 68:1499. PubMed
  62. Britton GJ et al. 2019. Immunity. 50(1):212-224 . PubMed
  63. Lyons J, et al. 2018. Sci Signal. 11. PubMed
  64. Moreau GB, et al. 2020. Am J Trop Med Hyg. 103:1215. PubMed
  65. Khan IM, et al. 2021. Immunohorizons. 5:703. PubMed
  66. Zhang J, et al. 2022. Front Immunol. 13:931740. PubMed
  67. Zhang C, et al. 2021. Clin Transl Immunology. 10:e1310. PubMed
  68. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  69. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  70. Bagayoko S, et al. 2021. PLoS Pathog. 17:e1009927. PubMed
  71. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  72. An J,et al. 2017. Sci Rep.. 10.1038/s41598-017-13629-0. PubMed
  73. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  74. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  75. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  76. Zeng J, et al. 2019. Cell Rep. 27:549. PubMed
  77. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  78. Škrnjug I, et al. 2014. PLoS One. 9:110150. PubMed
  79. Lee M, et al. 2014. PLoS One. 9:112666. PubMed
  80. Syed A, et al. 2015. Infect Immun . 83: 3428-3437. PubMed
  81. Zhang Y, et al. 2015. PLoS Pathog. 11: e1005167. PubMed
  82. Ben-Shaanan T, et al. 2016. Nat Med. 10.1038/nm.4133. PubMed
  83. Koren N, et al. 2021. Cell Host Microbe. 29(2):197-209.e5. PubMed
  84. Wu X, et al. 2021. Elife. 10:. PubMed
  85. Kelsey E Sivick et al. 2018. Cell reports. 25(11):3074-3085 . PubMed
  86. Fatkhullina AR et al. 2018. Immunity. 49(5):943-957 . PubMed
  87. Crosse EI, et al. 2020. Cell Stem Cell. 27:822. PubMed
  88. Sellau J, et al. 2016. Sci Rep. 6:28058. PubMed
  89. Rosen D, et al. 2016. J Infect Dis. 213: 649 - 658. PubMed
  90. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  91. Si Y, et al. 2018. J Control Release. 282:120. PubMed
  92. Baudoux T, et al. 2018. Sci Rep. 4.0375. PubMed
  93. Novkovic M, et al. 2016. PLoS Biol. 14: 1002515. PubMed
  94. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  95. Souza COS, et al. 2021. iScience. 24(6):102548. PubMed
  96. Connick K, et al. 2020. J Parasit Dis. 186:44. PubMed
  97. Johnson LA, et al. 2021. Life Sci Alliance. :4. PubMed
  98. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  99. Pan Y, et al. 2022. J Clin Invest. 132:. PubMed
  100. Christ A, et al. 2018. Cell. 172:162. PubMed
  101. Calcinotto A, et al. 2018. Nat Commun. 9:4832. PubMed
  102. Habib S, et al. 2018. Infect Immun. 86:e00019. PubMed
  103. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  104. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  105. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  106. Vettorazzi S, et al. 2015. Nat Commun. 6: 7796. PubMed
  107. Krollmann C, et al. 2022. STAR Protoc. 3:101309. PubMed
  108. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  109. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  110. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  111. Ercoli G, et al. 2022. Clin Transl Immunology. 11:e1366. PubMed
  112. Lewis EL, et al. 2021. Front Immunol. 12:741518. PubMed
  113. Panea C, et al. 2021. Commun Biol. 4:913. PubMed
  114. Moon HG et al. 2018. Immunity. 49(2):275-287 . PubMed
  115. Hiebert P et al. 2018. Developmental cell. 46(2):145-161 . PubMed
  116. Tran NT, et al. 2020. STAR Protocols. 1(1):100028. PubMed
  117. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  118. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  119. Gibbins J, et al. 2014. Blood. 124:2953. PubMed
  120. Schaefer K, et al. 2014. PLoS One. 9:114824. PubMed
  121. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  122. Kim SH, et al. 2021. Cell Reports. 35(2):108995. PubMed
  123. Nikolos F, et al. 2022. Nat Commun. 13:1487. PubMed
  124. Colombo M, et al. 2022. iScience. 25:105042. PubMed
  125. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  126. Yang C, et al. 2019. Nanomedicine (Lond). 14:2423. PubMed
  127. Janela B, et al. 2019. Immunity. 50:1069. PubMed
  128. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  129. Reimer E, et al. 2020. J Cell Sci. 134:00:00. PubMed
  130. Cuenca M, et al. 2016. J Immunol. 196: 726 - 737. PubMed
  131. Hayashi K, et al. 2015. Int Immunol. 27: 435-445. PubMed
  132. Ermert D, et al. 2016. PLoS Pathog. 11: 1005043. PubMed
  133. Puigdelloses M, et al. 2021. J Immunother Cancer. 9:. PubMed
  134. Daneshmandi S, et al. 2021. Elife. 10:. PubMed
  135. Henrich IC, et al. 2021. Cancer Res. 81:2171. PubMed
  136. Colliou N, et al. 2015. Toxins. 7: 3805 - 3817. PubMed
  137. Shepardson K, et al. 2016. MBio. 7: e00506-16. PubMed
  138. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  139. Lan H, et al. 2020. Int Immunol. 559:32. PubMed
  140. Taddio MF, et al. 2021. Mol Imaging Biol. 23:196. PubMed
  141. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  142. Yang X, et al. 2022. Front Immunol. 13:856230. PubMed
  143. Kim M, et al. 2018. Immunity. 49:151. PubMed
  144. Lu Y, et al. 2020. Immunity. 52:782. PubMed
  145. Dahlgren MW et al. 2019. Immunity. 50(3):707-722 . PubMed
  146. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  147. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  148. Zwick M, et al. 2019. Front Immunol. 10:222. PubMed
  149. Chan WY, et al. 2019. Infect Immun. 87:. PubMed
  150. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  151. Morikawa M, et al. 2016. PLoS One. 11:e0163607. PubMed
  152. Ghorbani S, et al. 2022. Nat Commun. 13:2445. PubMed
  153. Clement CC, et al. 2021. Immunity. 54:721. PubMed
  154. Andersen TK, et al. 2019. NPJ Vaccines. 4:9. PubMed
  155. Lai SM et al. 2018. Cell reports. 25(11):3099-3109 . PubMed
  156. Urata S, et al. 2018. PLoS Pathog. 14:e1007172. PubMed
  157. Zhao Y, et al. 2020. Immunity. 51(6):1059-1073.e9.. PubMed
  158. Hennion-Tscheltzoff O, et al. 2013. Blood. 121:4684. PubMed
  159. Škrnjug I, et al. 2014. PLoS One. 9:95728. PubMed
  160. Velázquez F, et al. 2016. J Immunol. 196: 1305 - 1316. PubMed
  161. Ghosh D, et al. 2016. J Immunol. 197: 1788 - 1800. PubMed
  162. Yasuda T, et al. 2016. PLoS One. 11:e0167952. PubMed
  163. Kumari P, et al. 2021. Cell Reports. 35(3):109012. PubMed
  164. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  165. Li E, et al. 2021. Front Immunol. 12:667177. PubMed
  166. He S, et al. 2021. Front Pharmacol. 12:743837. PubMed
  167. Wang L, et al. 2021. Sci Adv. 7:eabj4796. PubMed
  168. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  169. Niven J, et al. 2019. Cell Rep. 28:21. PubMed
  170. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  171. Harb H, et al. 2020. Nat Immunol. 1359:21. PubMed
  172. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  173. Porrello A, et al. 2018. Nat Commun. 9:1988. PubMed
  174. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  175. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  176. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  177. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  178. Di Pilato M, et al. 2021. Cell. 184(17):4512-4530.e22. PubMed
  179. Chung S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. L921:318. PubMed
  180. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  181. Donlan AN, et al. 2021. JCI Insight. 6: . PubMed
  182. Okreglicka K, et al. 2021. J Exp Med. 218:. PubMed
  183. Jin J, et al. 2020. Cell Reports. 30(12):4124-4136. PubMed
  184. Schuh E, et al. 2017. J Immunol. 198:3081. PubMed
  185. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  186. Van Nuffel E, et al. 2020. EMBO Rep. 21:e49237. PubMed
  187. Liu SS, et al. 2021. Immunity. :. PubMed
  188. Xu C, et al. 2021. Cell Reports. 35(11):109235. PubMed
  189. Hildreth AD, et al. 2020. STAR Protoc. 1:100113. PubMed
  190. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  191. Wan X, Thomas J, Unanue E 2016. J Exp Med. 213: 967 - 978. PubMed
  192. Yu H, et al. 2015. PLoS One. 10: 0143001. PubMed
  193. Stotesbury C, et al. 2020. Aging Cell. 19:e13170. PubMed
  194. Teng F, et al. 2021. Cell Rep. 37:110051. PubMed
  195. Ceglia V, et al. 2021. J Immunol. 207:2060. PubMed
  196. Bahmani B, et al. 2021. Nat Commun. 12:1999. PubMed
  197. Fite BZ, et al. 2021. Sci Rep. 11:927. PubMed
  198. Lee HN, et al. 2022. JCI Insight. 7:. PubMed
  199. Verma M, et al. 2021. J Exp Med. 218:. PubMed
  200. Kim J, et al. 2020. Adv Funct Mater. 30:. PubMed
  201. Lee GR, et al. 2021. JCI Insight. 6:. PubMed
  202. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  203. Albaghdadi AJH, et al. 2019. Sci Rep. 9:6528. PubMed
  204. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  205. Crowe J, et al. 2020. PLoS Pathog. 16:e1008391. PubMed
  206. Saleh R, et al. 2018. J Immunol. 201:2042. PubMed
  207. Doo DW, et al. 2020. Ther Adv Med Oncol. 12:1758835920913798. PubMed
  208. Stack G, et al. 2015. PLoS Pathog. 11:1004641. PubMed
  209. Tran S, et al. 2020. Immunity. 53(3):627-640.e5. PubMed
  210. Goc J, et al. 2021. Cell. 184:5015. PubMed
  211. Schäfer AL, et al. 2021. Front Immunol. 12:696810. PubMed
  212. Hsu HP, et al. 2021. J Biol Chem. 296:100419. PubMed
  213. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  214. Dietschmann A, et al. 2020. Eur J Immunol. 50:1044. PubMed
  215. Thomson CA, et al. 2018. J Immunol. 201:215. PubMed
  216. Chen S, et al. 2018. Nat Commun. 9:5298. PubMed
  217. Dai B, et al. 2021. Cell Reports Medicine. 2(8):100381. PubMed
  218. Trivedi S, et al. 2020. Elife. 9:00. PubMed
  219. Hayashi K, et al. 2020. Nat Commun. 4.832638889. PubMed
  220. Fontana C, et al. 2016. J Biol Chem. 291: 7727-7741. PubMed
  221. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
  222. Wirasinha RC, et al. 2021. J Exp Med. 218: . PubMed
  223. Zhang Y, et al. 2022. J Immunother Cancer. 10:. PubMed
  224. Lee S, et al. 2021. Autophagy. 18:1062. PubMed
  225. Amend A, et al. 2021. Int J Mol Sci. 22:. PubMed
RRID
AB_493569 (BioLegend Cat. No. 117317)
AB_493568 (BioLegend Cat. No. 117318)

Antigen Details

Structure
Integrin α-chain, associates with integrin β2 (CD18), 150 kD
Distribution

Dendritic cells, NK cells, intestinal intraepithelial lymphocytes (IEL), some activated T cells

Function
Cellular adhesion
Ligand/Receptor
iC3b, fibrinogen
Cell Type
Dendritic cells, Epithelial cells, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen Facts Book Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lopez-Rodriguez C, et al. 1996. J. Immunol. 156:3780.

Gene ID
16411 View all products for this Gene ID
UniProt
View information about CD11c on UniProt.org

Other Formats

View All CD11c Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD11c N418 FC
Biotin anti-mouse CD11c N418 FC,IHC-F
FITC anti-mouse CD11c N418 FC
PE anti-mouse CD11c N418 FC
Purified anti-mouse CD11c N418 FC,CyTOF®,IP,IHC
Alexa Fluor® 488 anti-mouse CD11c N418 FC
Alexa Fluor® 647 anti-mouse CD11c N418 FC,IHC,ICC,3D IHC
PE/Cyanine5 anti-mouse CD11c N418 FC
PE/Cyanine7 anti-mouse CD11c N418 FC
Brilliant Violet 605™ anti-mouse CD11c N418 FC
Alexa Fluor® 700 anti-mouse CD11c N418 FC
Pacific Blue™ anti-mouse CD11c N418 FC
APC/Cyanine7 anti-mouse CD11c N418 FC
PerCP/Cyanine5.5 anti-mouse CD11c N418 FC
PerCP anti-mouse CD11c N418 FC
Brilliant Violet 421™ anti-mouse CD11c N418 FC,IHC
Brilliant Violet 570™ anti-mouse CD11c N418 FC
Brilliant Violet 785™ anti-mouse CD11c N418 FC
Brilliant Violet 510™ anti-mouse CD11c N418 FC
Brilliant Violet 650™ anti-mouse CD11c N418 FC
Purified anti-mouse CD11c (Maxpar® Ready) N418 FC,CyTOF®
Alexa Fluor® 594 anti-mouse CD11c N418 IHC-F,3D IHC
PE/Dazzle™ 594 anti-mouse CD11c N418 FC
Brilliant Violet 711™ anti-mouse CD11c N418 FC
APC/Fire™ 750 anti-mouse CD11c N418 FC
TotalSeq™-A0106 anti-mouse CD11c N418 PG
Brilliant Violet 750™ anti-mouse CD11c N418 FC
TotalSeq™-B0106 anti-mouse CD11c N418 PG
TotalSeq™-C0106 anti-mouse CD11c N418 PG
KIRAVIA Blue 520™ anti-mouse CD11c N418 FC
Spark Blue™ 550 anti-mouse CD11c N418 FC
Spark NIR™ 685 anti-mouse CD11c N418 FC
Spark UV™ 387 anti-mouse CD11c N418 FC
Spark Red™ 718 anti-mouse CD11c N418 FC
Spark Blue™ 515 anti-mouse CD11c N418 FC
PerCP/Fire™ 806 anti-mouse CD11c N418 FC
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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