APC anti-mouse CD11c Antibody

Pricing & Availability
Clone
N418 (See other available formats)
Regulatory Status
RUO
Other Names
αX integrin, integrin αX chain, CR4, p150, ITGAX
Isotype
Armenian Hamster IgG
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Product Citations
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N418
C57BL/6 mouse splenocytes stained with N418 APC and PK136 PE
  • N418
    C57BL/6 mouse splenocytes stained with N418 APC and PK136 PE
Compare all formats See APC spectral data
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117309 25 µg $33
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117310 100 µg $116
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Description

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse spleen dendritic cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11c antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9 (Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.

Application References

(PubMed link indicates BioLegend citation)
  1. Granucci F, et al. 1997. J. Immunol. 159:1794.
  2. Stokes RW, et al. 1998. J. Immunol. 160:5514.
  3. Metlay JP, et al. 1990. J. Exp. Med. 171:1753. (IHC, IP)
  4. Ma XT, et al. 2006. Cancer Research 66:1169.
  5. Chin RK, et al. 2006. J. Immunol. 177:290. (IF)
  6. Cervantes-Barragan L, et al. 2007. Blood 109:1131. (FC) PubMed
  7. Turnquist HR, et al. 2007. J. Immunol. 178:7018. (FC) PubMed
  8. Benson MJ, et al. 2007. J. Exp. Med. doi:10.1084/jem.20070719. (FC) PubMed
  9. You Y, et al. 2009. J. Immunol. 182:7343. (IF) PubMed
  10. Roland CL, et al. 2009. Mol. Cancer Res. 8:1761. (IHC, FC) PubMed
  11. Wikstrom M, et al.2006. J. Immunol. 177:913. PubMed
  12. Pericolini E, et al. 2008. J. Leukocyte Biol. 83:1286. PubMed
  13. Randall LM, et al. 2008. Infect. Immun.76:3312. PubMed
  14. Fahlen-Yrild L, et al. 2009. J. Immunol. 183:5032. PubMed
  15. Osterholzer JJ, et al. 2009. J. Immunol. 183:8044. PubMed
  16. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed
  17. Eisenach PA, et al. 2010. J Cell Sci. 123:4182. PubMed
  18. Leppin K, et al. 2014. Invest. Ophthalmol. Vis. Sci. 55:3603. PubMed
  19. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  20. Gibbins JD, et al. 2014. Blood. 124:2953. PubMed
  21. White CE, et al. 2015. J Immunol. 194:697. PubMed
  22. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  23. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  24. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Ramakrishna C, et al. 2019. Nat Commun. 10:2153. PubMed
  2. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  3. Kawabe T, et al. 2020. Nat Commun. 2.795833333. PubMed
  4. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  5. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  6. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  7. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  8. Minute L, et al. 2020. J Immunother Cancer. 8:. PubMed
  9. Michalaki C, et al. 2022. Curr Protoc. 2:e505. PubMed
  10. Narusawa M, et al. 2014. Cancer Immunol Res. 2:568. PubMed
  11. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  12. Lin C, et al. 2020. Cancer Immunol Res. 632:8. PubMed
  13. Zhang LJ, et al. 2019. Immunity. 50:121. PubMed
  14. Shi L, et al. 2019. Theranostics. 9:4115. PubMed
  15. Page N, et al. 2018. Immunity. 48:937. PubMed
  16. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  17. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  18. Kitai H, et al. 2022. BMC Biol. 20:248. PubMed
  19. Tan L, et al. 2022. Biochem Biophys Rep. 32:101351. PubMed
  20. Li Q, et al. 2022. Cell Rep. 40:111308. PubMed
  21. Lefebvre MN, et al. 2021. Cell Rep. 37:109956. PubMed
  22. Jiang Q, et al. 2022. Theranostics. 12:59. PubMed
  23. Zhou J, et al. 2021. Int J Med Sci. 18:3516. PubMed
  24. Meng W, et al. 2021. JCI Insight. 6:. PubMed
  25. Miller CM, et al. 2020. J Virol. 94:00:00. PubMed
  26. Gujar R, et al. 2016. J Immunol. 197: 1650 - 1662. PubMed
  27. Nocera D, et al. 2016. J Immunol. 196: 2860 - 2869. PubMed
  28. Riva A, et al. 2013. J Immunol. 190:5961. PubMed
  29. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  30. Kim TJ, et al. 2019. Nat Commun. 10:3258. PubMed
  31. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  32. Kunimura K, et al. 2020. Cell Reports. 29(9):2823-2834.e7.. PubMed
  33. Pandey S, et al. 2020. Cell Syst. 11:495. PubMed
  34. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  35. Sauter M, et al. 2022. iScience. 25:103677. PubMed
  36. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  37. Xia S, et al. 2014. J Leukoc Biol. 95:733. PubMed
  38. Aguilera T, et al. 2016. Nat Commun. 7:13898. PubMed
  39. He Y, et al. 2020. Sci Adv. 6:eaba7589. PubMed
  40. Blumenthal D, et al. 2020. eLife. 9:e55995.. PubMed
  41. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  42. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  43. Shin M et al. 2019. Cell Chem Biol. 26(7):1036-1041 . PubMed
  44. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  45. Zhao J, et al. 2019. Nat Commun. 10:899. PubMed
  46. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  47. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  48. Liang W, et al. 2022. Methods Mol Biol. 2574:221. PubMed
  49. Wiernicki B, et al. 2022. Nat Commun. 13:3676. PubMed
  50. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  51. Chen WS, et al. 2021. Cell Rep. 37:109974. PubMed
  52. Klarquist J, et al. 2021. Cell Rep. 36:109591. PubMed
  53. Nam J, et al. 2021. Adv Sci (Weinh). 2002577:8. PubMed
  54. de Mingo Pulido , et al. 2021. Immunity. 54(6):1154-1167.e7. PubMed
  55. Coppo M, et al. 2016. Nat Commun. 7:12254. PubMed
  56. Wegmann F, et al. 2015. Clin Vaccine Immunol. 22: 1004-1012. PubMed
  57. Qian F, et al. 2015. J Mol Cell Biol. . PubMed
  58. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  59. Bode K, et al. 2020. Cell Reports. 29(13):4435-4446.e9.. PubMed
  60. Wiede F, et al. 2021. Cancer Discov. Online ahead of print. PubMed
  61. Zhou HF, et al. 2022. Front Pharmacol. 13:778755. PubMed
  62. Helm M, et al. 2022. Life (Basel). 12:. PubMed
  63. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  64. Prado C, et al. 2012. J Immunol. 188:3062. PubMed
  65. Angelidis I, et al. 2019. Nat Commun. 10:963. PubMed
  66. Cao W, et al. 2017. Immunity. 47:1182. PubMed
  67. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  68. Sharma PK, et al. 2018. Cancer Gene Ther. 25:27. PubMed
  69. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  70. Hao F, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  71. Kulkarni NN, et al. 2021. J Biol Chem. 297:100828. PubMed
  72. Yu AI, et al. 2020. Cell Rep. 107471:31. PubMed
  73. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  74. O'Shea NR, Chew TS 2016. J Crohns Colitis. 10(12):1417-1427. PubMed
  75. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  76. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  77. Lin SY, et al. 2017. Autophagy. 14:778. PubMed
  78. Yuan B, et al. 2021. J Immunother Cancer. 9:. PubMed
  79. Jing L, et al. 2022. Front Immunol. 13:864995. PubMed
  80. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  81. Wang B, et al. 2022. Nat Commun. 13:3821. PubMed
  82. Dos Santos Dias L, et al. 2021. PLoS Pathog. e1009324:17. PubMed
  83. Bertino P, et al. 2019. Oncoimmunology. 8:1601482. PubMed
  84. Lisk C, et al. 2020. Front Immunol. 1.329166667. PubMed
  85. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  86. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  87. Liu D et al. 2019. Immunity. 51(1):64-76 . PubMed
  88. Matsumura T et al. 2019. Cell Rep. 27(2):561-571 . PubMed
  89. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  90. McAlpine CS, et al. 2021. Nature. 595:701. PubMed
  91. Stump CT, et al. 2021. Open Biol. 11:210245. PubMed
  92. Dokoshi T, et al. 2021. J Clin Invest. 131:. PubMed
  93. Marjanovic ND, et al. 2020. Cancer Cell. 38(2):229-246.e13. PubMed
  94. Wang Y, et al. 2021. Sci Rep. 1.429861111. PubMed
  95. Sellau J, et al. 2016. Sci Rep. 6:28058. PubMed
  96. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  97. Madan-Lala R, et al. 2014. J Immunol. 192:4263. PubMed
  98. Bunn P, et al. 2014. J Immunol. 192:3709. PubMed
  99. Ustarroz-Cano M, et al. 2012. J Immunotoxicol. 9:374. PubMed
  100. Bak S, et al. 2008. Mol Immunol. 45:1414. PubMed
  101. Kooreman NG et al. 2018. Cell stem cell. 22(4):501-513 . PubMed
  102. Xu H, et al. 2020. Immunity. 51(4):696-708.e9.. PubMed
  103. Suryawanshi RK, et al. 2021. Nat Commun. 12:6020. PubMed
  104. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  105. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  106. Cho YK, et al. 2022. Nat Commun. 13:4084. PubMed
  107. Zou J, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:983. PubMed
  108. Li W, et al. 2021. Front Pharmacol. 12:697483. PubMed
  109. Glauser D, et al. 2013. J Virol. 87:10828. PubMed
  110. Aebischer D, et al. 2014. PLoS One. 9:99297. PubMed
  111. Spinner C, et al. 2015. Sci Rep. 5:16269. PubMed
  112. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  113. Li N, et al. 2021. eLife. 10:00. PubMed
  114. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  115. Gozgit JM, et al. 2021. Cancer Cell. :. PubMed
  116. Cheng Y, et al. 2020. PLoS Pathog. 16:e1008569. PubMed
  117. Dmitrieva‐Posocco O et al. 2019. Immunity. 50(1):166-180 . PubMed
  118. Yadava K et al. 2019. Elife. 8 pii: e44821. PubMed
  119. Garo LP, et al. 2019. Cell Rep. 28:3353. PubMed
  120. Budida R, et al. 2017. Eur J Immunol. 47:1819. PubMed
  121. Niknam S, et al. 2018. Clin Cancer Res. 24:5735. PubMed
  122. Miteva K, et al. 2018. Sci Rep. 8:2820. PubMed
  123. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  124. Zhang C, et al. 2022. Nat Commun. 13:3468. PubMed
  125. Xu M, et al. 2022. Genes Dis. 9:429. PubMed
  126. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  127. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  128. Liu M, et al. 2016. PLoS One. 11:e0166165. PubMed
  129. Markey K, et al. 2014. J Immunol. 192:5426. PubMed
  130. Platteel A, et al. 2017. Vaccine.. 10.1016/j.vaccine.2017.10.044. PubMed
  131. Hu J, et al. 2019. Mol Ther Nucleic Acids. 16:650. PubMed
  132. He J, et al. 2019. J Clin Invest. 130. PubMed
  133. Kemp V, et al. 2018. Cancer Gene Ther. 26:268. PubMed
  134. Kramer K, et al. 2017. ACS Omega. 0.240972222. PubMed
  135. Liu W, et al. 2019. Epigenetics. 1.192361111. PubMed
  136. Marsh L, et al. 2009. Am J Physiol Lung Cell Mol Physiol. 296:L442. PubMed
  137. Yang Y, et al. 2021. Sci Adv. 7:eabf6290. PubMed
  138. Kim S, et al. 2021. Elife. 10:. PubMed
  139. Gibbins J, et al. 2014. Blood. 124:2953. PubMed
  140. White C, et al. 2015. J Immunol. 194:697. PubMed
  141. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  142. Wanner-Seleznik GM, et al. 2020. Immunohorizons. 0.644444444. PubMed
  143. Liu Z, et al. 2021. Immunity. 54(2):247-258.e7. PubMed
  144. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  145. Zeng W, et al. 2021. STAR Protocols. 2(1):100361. PubMed
  146. Liu Z, et al. 2020. Cell. 178(6):1509-1525.e19.. PubMed
  147. Yahagi A, et al. 2019. RMD Open. 5:e000853. PubMed
  148. Xia P et al. 2018. Immunity. 48(4):688-701 . PubMed
  149. Nam GH, et al. 2018. Nat Commun. 9:2165. PubMed
  150. Lang V, et al. 2021. Elife. 10:. PubMed
  151. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  152. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  153. Li C, et al. 2021. Cell Metabolism. 33(8):1610-1623.e5. PubMed
  154. Dobson HE, et al. 2020. Mucosal Immunol. 0.901388889. PubMed
  155. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  156. Mainini F, et al. 2015. PLoS One. 10: 0145403. PubMed
  157. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  158. Ye Y, et al. 2017. Sci Immunol. 2:17. PubMed
  159. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  160. Trinh HKT, et al. 2019. J Cell Mol Med. 23:3441. PubMed
  161. Fischer FA, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  162. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  163. Tukaramrao DB, et al. 2021. Cancers (Basel). 13:. PubMed
  164. Wüthrich M, et al. 2021. MBio. 12:e0201821. PubMed
  165. Schneider KM, et al. 2022. Nat Commun. 13:3964. PubMed
  166. Kohn EM, et al. 2022. J Immunol. 208:1417. PubMed
  167. Wang Y, et al. 2022. J Control Release. 349:118. PubMed
  168. Takaki H, et al. 2013. J Immunol. 191:4740. PubMed
  169. Wang H, et al. 2020. Nat Mater. 1.655555556. PubMed
  170. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  171. Chitu V, et al. 2020. Cell Reports. 30(9):3004-3019. PubMed
  172. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  173. Yamada S, et al. 2018. Arterioscler Thromb Vasc Biol. 38:994. PubMed
  174. Chu LH, et al. 2018. Nat Commun. 9:996. PubMed
  175. Tang Z, et al. 2021. Stem Cell Res Ther. 12:397. PubMed
  176. Zhang XW, et al. 2021. Oncoimmunology. 10:1920739. PubMed
  177. Li X, et al. 2021. Cell Death Dis. 12:314. PubMed
  178. Shan B, et al. 2020. Nat Metab. 1332:2. PubMed
  179. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  180. Peng X, et al. 2016. J Cell Sci. 129: 1831 - 1842. PubMed
  181. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  182. Li C, et al. 2018. Cell. 174:285. PubMed
  183. Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
  184. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  185. Carlson PM, et al. 2021. J Immunol. 207:720. PubMed
  186. Woodring T, et al. 2022. iScience. 25:104934. PubMed
  187. Berthold N, et al. 2013. Antimicrob Agents Chemother. 57:402. PubMed
  188. Upadhya R, et al. 2016. MBio. 7: 00547-16. PubMed
  189. Onai N, et al. 2020. Int J Mol Sci. :22. PubMed
  190. McCauley ME, et al. 2020. Nature. 585(7823):96-101. PubMed
  191. Qian Z, et al. 2022. Biomedicines. 10:. PubMed
  192. Bezu L, et al. 2022. J Immunother Cancer. 10:. PubMed
  193. Huang T, et al. 2022. Nat Commun. 13:3489. PubMed
  194. Vogel A, et al. 2022. Cell Rep. 38:110420. PubMed
  195. Sebina I, et al. 2016. PLoS Pathog. 12:e1005999. PubMed
  196. Zhao W, et al. 2014. Clin Vaccine Immunol. 21:74. PubMed
  197. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  198. Wang S, et al. 2020. J Cell Mol Med. 24:722. PubMed
  199. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  200. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  201. Jiang Y, et al. 2021. Nat Commun. 12:742. PubMed
  202. Lisk C, et al. 2021. Front Immunol. 12:624197. PubMed
  203. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  204. Takahashi N, et al. 2022. Tohoku J Exp Med. 257:171. PubMed
  205. Grube J, et al. 2022. Cell Death Dis. 13:704. PubMed
  206. Liu Q, et al. 2021. Adv Mater. 33:e2102852. PubMed
  207. Sobecki M, et al. 2022. Cell Stem Cell. 29:1459. PubMed
  208. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  209. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  210. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  211. Kramer K, et al. 2017. Mol Ther. 25(1):62-70. PubMed
  212. Yin X, et al. 2020. Cell Rep. 33:108278. PubMed
  213. Huang WC, et al. 2020. Adv Mater. 32:e2005637. PubMed
  214. Huang WC, et al. 2020. NPJ Vaccines. 5:23. PubMed
  215. Kunishita Y, et al. 2020. Front Immunol. 11:98. PubMed
  216. Wang C, et al. 2018. Sci Transl Med. 10. PubMed
  217. Dye BR, et al. 2020. Biomaterials. 234:119757. PubMed
  218. Shen H, et al. 2022. Nat Commun. 13:5013. PubMed
  219. Smith LK, et al. 2021. Elife. 10:. PubMed
  220. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  221. Li H, et al. 2022. iScience. 25:104481. PubMed
  222. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  223. Boulch M, et al. 2021. Sci Immunol. 6:. PubMed
  224. Nicholls J, et al. 2021. Front Cell Dev Biol. 9:737880. PubMed
  225. Huang WC, et al. 2020. NPJ Vaccines. 5:23. PubMed
  226. Ryu S, et al. 2021. eLife. 0.416666666666667. PubMed
  227. Wang Y, et al. 2021. Nat Commun. 0.570833333. PubMed
  228. Aguilera TA, et al. 2020. Clin Cancer Res. 26:2972. PubMed
  229. Martins R, et al. 2016. Nat Immunol. 17:1361-1372. PubMed
  230. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  231. Dyer DP et al. 2019. Immunity. 50(2):378-389 . PubMed
  232. Sadtler K, et al. 2017. Tissue Eng Part A. 23:1044. PubMed
  233. Matisz CE, et al. 2018. Am J Pathol. 188:2589. PubMed
  234. Hong Y, et al. 2019. J Extracell Vesicles. 8:1670893. PubMed
  235. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  236. Zhang B, et al. 2021. Nature. 599:471. PubMed
  237. Wang X, et al. 2021. Sci Transl Med. 13:. PubMed
  238. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  239. Gawish R, et al. 2022. Elife. 11:. PubMed
  240. Gentschev I, et al. 2012. PLoS One. 7:e37239. PubMed
  241. Brenner E, et al. 2020. Nat Commun. 11:1335. PubMed
  242. Morrissey MA, et al. 2018. Elife. 7:e36688. PubMed
  243. Kubli SP, et al. 2019. Nat Commun. 10:2678. PubMed
  244. Yáñez A et al. 2017. Immunity. 47(5):890-902 . PubMed
  245. Yu L, et al. 2022. Front Immunol. 13:937331. PubMed
  246. Sethuraman SN, et al. 2020. Theranostics. 10:3397. PubMed
  247. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  248. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  249. Akhtar MN, et al. 2020. PLoS Pathog. 16:e1009136. PubMed
  250. Shi GN, et al. 2021. Ther Adv Med Oncol. 13:1758835920987056. PubMed
  251. Rana MN, et al. 2021. Front Pharmacol. 12:643215. PubMed
  252. Cortez MA, et al. 2020. Nat Commun. 3.819444444. PubMed
RRID
AB_313778 (BioLegend Cat. No. 117309)
AB_313779 (BioLegend Cat. No. 117310)

Antigen Details

Structure
Integrin α-chain, associates with integrin β2 (CD18), 150 kD
Distribution

Dendritic cells, NK cells, intestinal intraepithelial lymphocytes (IEL), some activated T cells

Function
Cellular adhesion
Ligand/Receptor
iC3b, fibrinogen
Cell Type
Dendritic cells, Epithelial cells, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen Facts Book Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lopez-Rodriguez C, et al. 1996. J. Immunol. 156:3780.

Gene ID
16411 View all products for this Gene ID
UniProt
View information about CD11c on UniProt.org

Related FAQs

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Other Formats

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Description Clone Applications
APC anti-mouse CD11c N418 FC
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Alexa Fluor® 488 anti-mouse CD11c N418 FC
Alexa Fluor® 647 anti-mouse CD11c N418 FC,IHC,ICC,3D IHC
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Pacific Blue™ anti-mouse CD11c N418 FC
APC/Cyanine7 anti-mouse CD11c N418 FC
PerCP/Cyanine5.5 anti-mouse CD11c N418 FC
PerCP anti-mouse CD11c N418 FC
Brilliant Violet 421™ anti-mouse CD11c N418 FC,IHC
Brilliant Violet 570™ anti-mouse CD11c N418 FC
Brilliant Violet 785™ anti-mouse CD11c N418 FC
Brilliant Violet 510™ anti-mouse CD11c N418 FC
Brilliant Violet 650™ anti-mouse CD11c N418 FC
Purified anti-mouse CD11c (Maxpar® Ready) N418 FC,CyTOF®
Alexa Fluor® 594 anti-mouse CD11c N418 IHC-F,3D IHC
PE/Dazzle™ 594 anti-mouse CD11c N418 FC
Brilliant Violet 711™ anti-mouse CD11c N418 FC
APC/Fire™ 750 anti-mouse CD11c N418 FC
TotalSeq™-A0106 anti-mouse CD11c N418 PG
Brilliant Violet 750™ anti-mouse CD11c N418 FC
TotalSeq™-B0106 anti-mouse CD11c N418 PG
TotalSeq™-C0106 anti-mouse CD11c N418 PG
KIRAVIA Blue 520™ anti-mouse CD11c N418 FC
Spark Blue™ 550 anti-mouse CD11c N418 FC
Spark NIR™ 685 anti-mouse CD11c N418 FC
Spark UV™ 387 anti-mouse CD11c N418 FC
Spark Red™ 718 anti-mouse CD11c N418 FC
Spark Blue™ 515 anti-mouse CD11c N418 FC
PerCP/Fire™ 806 anti-mouse CD11c N418 FC
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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