- Clone
- ZM4.1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Immunoglobulin-like transcript (ILT) 3, CD85k, Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4), Leukocyte Immunoglobulin-like Receptor 5 (LIR-5)
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications

-
Human monocyte-derived dendritic cells stained with ZM4.1 PE
Cat # | Size | Price | Quantity Check Availability | Save | ||
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333007 | 25 tests | £100 | ||||
333008 | 100 tests | £217 |
CD85k, known as Immunoglobulin-like transcript (ILT) 3, is an inhibitory receptor expressed by dendritic cells and a subset of white blood cells called monocytes. ILT3, also known as Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4) and Leukocyte Immunoglobulin-like Receptor 5 (LIR-5), is a type I membrane protein that contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses. Expression of ILT3 is up-regulated on tolerogenic dendritic cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- ILT3 fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- RRID
-
AB_1027680 (BioLegend Cat. No. 333007)
AB_2136645 (BioLegend Cat. No. 333008)
Antigen Details
- Structure
- Immunoglobulin superfamily
- Distribution
- Monocytes, Macrophages, and Dendritic Cells
- Cell Type
- Monocytes, Macrophages, Dendritic cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Cella M, et al. 1997. J. Exp. Med. 185:1743.
2. Penna G, et al. 2005 Blood 5:2044. - Gene ID
- 11006 View all products for this Gene ID
- UniProt
- View information about CD85k on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD85k Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD85k (ILT3) | ZM4.1 | FC |
PE anti-human CD85k (ILT3) | ZM4.1 | FC |
Alexa Fluor® 647 anti-human CD85k (ILT3) | ZM4.1 | FC |
PE/Cyanine7 anti-human CD85k (ILT3) | ZM4.1 | FC |
PerCP/Cyanine5.5 anti-human CD85k (ILT3) | ZM4.1 | FC |
APC anti-human CD85k (ILT3) | ZM4.1 | FC |
TotalSeq™-B1248 anti-human CD85k (ILT3) | ZM4.1 | PG |
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