- Clone
- ZM4.1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Immunoglobulin-like transcript (ILT) 3, CD85k, Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4), Leukocyte Immunoglobulin-like Receptor 5 (LIR-5)
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications

-
Human peripheral blood lymphocytes were stained with CD123 APC and CD85k (ILT3) (clone ZM4.1) PE/Cyanine7 (top image) or mouse IgG1, κ PE/Cyanine7 isotype control (bottom image). -
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
333011 | 25 tests | £109 | ||||
333012 | 100 tests | £254 |
CD85k, known as Immunoglobulin-like transcript (ILT) 3, is an inhibitory receptor expressed by dendritic cells and a subset of white blood cells called monocytes. ILT3, also known as Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4) and Leukocyte Immunoglobulin-like Receptor 5 (LIR-5), is a type I membrane protein that contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses. Expression of ILT3 is up-regulated on tolerogenic dendritic cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- ILT3 fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- RRID
-
AB_2564066 (BioLegend Cat. No. 333011)
AB_2564067 (BioLegend Cat. No. 333012)
Antigen Details
- Structure
- Immunoglobulin superfamily
- Distribution
- Monocytes, Macrophages, and Dendritic Cells
- Cell Type
- Monocytes, Macrophages, Dendritic cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Cella M, et al. 1997. J. Exp. Med. 185:1743.
2. Penna G, et al. 2005 Blood 5:2044. - Gene ID
- 11006 View all products for this Gene ID
- UniProt
- View information about CD85k on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All CD85k Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD85k (ILT3) | ZM4.1 | FC |
PE anti-human CD85k (ILT3) | ZM4.1 | FC |
Alexa Fluor® 647 anti-human CD85k (ILT3) | ZM4.1 | FC |
PE/Cyanine7 anti-human CD85k (ILT3) | ZM4.1 | FC |
PerCP/Cyanine5.5 anti-human CD85k (ILT3) | ZM4.1 | FC |
APC anti-human CD85k (ILT3) | ZM4.1 | FC |
TotalSeq™-B1248 anti-human CD85k (ILT3) | ZM4.1 | PG |
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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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