- SP8 (See other available formats)
- Other Names
- Syntaxin-1A, neuron-specific antigen HPC-1
- Mouse IgG1
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- Product Citations
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Syntaxin, also known as syntaxin-1A and neuron-specific antigen HPC-1, is part of the Q-SNARE protein family that participates in exocytosis. Syntaxins have a SNARE domain, an N-terminal regulatory domain, and a single C-terminal transmembrane domain. Syntaxin drives the spontaneous calcium-independent fusion of synaptic vesicles that contain v-SNARE proteins, and may form part of the fusion pore of exocytosis.Product Details
- Human, Mouse, Rat
- Antibody Type
- Host Species
- This monoclonal antibody was raised against a crude synaptic preparation from a post-mortem human brain.
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
WB - Quality tested
IHC-P - Validated
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.05 - 0.5 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application. For immunohistochemistry, a concentration range of 2.5 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody is effective in immunohistochemistry (IHC-P) and western blotting (WB).
(PubMed link indicates BioLegend citation)
- Honer WG, et al. 1997. Neuroscience 78(1):99-110.
- Honer WG, et al. 1993. Brain Res. 609(1-2):9-20.
AB_2801168 (BioLegend Cat. No. 827005)
AB_2801169 (BioLegend Cat. No. 827006)
- How many biotin molecules are per antibody structure?
- We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
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