- SP8 (See other available formats)
- Other Names
- Syntaxin-1A, neuron-specific antigen HPC-1
- Mouse IgG1
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- Product Citations
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Syntaxin, also known as syntaxin-1A and neuron-specific antigen HPC-1, is part of the Q-SNARE protein family that participates in exocytosis. Syntaxins have a SNARE domain, an N-terminal regulatory domain, and a single C-terminal transmembrane domain. Syntaxin drives the spontaneous calcium-independent fusion of synaptic vesicles that contain v-SNARE proteins, and may form part of the fusion pore of exocytosis.Product Details
- Human, Mouse, Rat
- Antibody Type
- Host Species
- This monoclonal antibody was raised against a crude synaptic preparation from a post-mortem human brain.
- This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
- The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, the antibody solution should be stored undiluted at -20°C.
WB - Quality tested
IHC-P - Validated
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.02 - 1.0 µg per ml. For immunohistochemistry on formalin-fixed paraffin-embedded tissue, a concentration range of 5.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody is effective in immunohistochemistry (IHC-P) and Western Blotting (WB).
(PubMed link indicates BioLegend citation)
- Honer WG, et al. 1997. Neuroscience 78(1):99-110.
- Honer WG, et al. 1993. Brain Res. 609(1-2):9-20.
AB_2783400 (BioLegend Cat. No. 827003)
AB_2783401 (BioLegend Cat. No. 827004)
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