Loading...

APC/Cyanine7 anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
30-F11_APCCyanine7_CD45_Antibody_013019_updated.png
C57BL/6 splenocytes were stained with CD45 (clone 30-F11) APC/Cyanine7 (filled histogram) or Rat IgG2b, ? APC/Cyanine7 isotype control (open histogram).
  • 30-F11_APCCyanine7_CD45_Antibody_013019_updated.png
    C57BL/6 splenocytes were stained with CD45 (clone 30-F11) APC/Cyanine7 (filled histogram) or Rat IgG2b, ? APC/Cyanine7 isotype control (open histogram).
Compare all formats See APC/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
103115 25 µg 79€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
103116 100 µg 157€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Additional Product Notes
BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Cignarella F et al. 2018. Cell metabolism. 27(6):1222-1235 . PubMed
  2. Contijoch EJ et al. 2019. eLife. 8 pii: e40553. PubMed
  3. Wu J et al. 2017. Immunity. 47(6):1114-1128 . PubMed
  4. Komuczki J, et al. 2019. Immunity. 50:1289. PubMed
  5. Wang X, et al. 2019. Cell Res. 29:787. PubMed
  6. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  7. Heindl S, et al. 2021. J Exp Med. 218:. PubMed
  8. Stefkovich M, et al. 2021. Mol Metab. 54:101357. PubMed
  9. Wang Q, et al. 2020. Radiat Environ Biophys. 59:89. PubMed
  10. Kim MY, et al. 2021. JCI Insight. 6:. PubMed
  11. De Vries LCS, et al. 2021. J Crohns Colitis. 15:617. PubMed
  12. Bernasconi R, et al. 2021. EMBO Mol Med. :e14392. PubMed
  13. Miranda K, et al. 2022. iScience. 25:104994. PubMed
  14. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  15. Furrer R, et al. 2021. Sci Adv. 7:eabi4852. PubMed
  16. Ren D, et al. 2022. STAR Protoc. 3:101217. PubMed
  17. Chang YS, et al. 2020. Int J Mol Sci. 21:00. PubMed
  18. Naito H, et al. 2020. Nature Protocols. 15(3):1066-1081. PubMed
  19. Xing J, et al. 2021. Cell Reports. 35(12):109205. PubMed
  20. Page N, et al. 2018. Immunity. 48:937. PubMed
  21. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  22. Ajina R, et al. 2019. Oncoimmunology. 8:e1577127. PubMed
  23. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  24. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  25. Lyons J, et al. 2018. PLoS Biol. 16:e2002417. PubMed
  26. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  27. Wu SY, et al. 2022. Mol Cancer. 21:84. PubMed
  28. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  29. Jiang Q, et al. 2022. Theranostics. 12:59. PubMed
  30. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  31. Fan L, et al. 2021. Cancers (Basel). 13:. PubMed
  32. Urban SK, et al. 2020. Liver Int. 40:3103. PubMed
  33. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  34. Rosenkranz SC, et al. 2021. eLife. 10:00. PubMed
  35. Kokona D, et al. 2016. Exp Eye Res. S0014-4835(16)30499-7. PubMed
  36. Ebneter A, et al. 2017. Transl Vis Sci Technol. 10.1167/tvst.6.2.10. PubMed
  37. Kim TJ, et al. 2019. Nat Commun. 10:3258. PubMed
  38. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
  39. Blecher-Gonen R, et al. 2019. Cell Syst. 8:109. PubMed
  40. Kashyap AS, et al. 2019. Cell Rep. 28:3367. PubMed
  41. Pluchino N, et al. 2020. J Cell Mol Med. 24:2464. PubMed
  42. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  43. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  44. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  45. Baram T, et al. 2021. Cells. 10:. PubMed
  46. Pan Y, et al. 2021. Front Cell Neurosci. 15:664312. PubMed
  47. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  48. Luo R, et al. 2021. Theranostics. 11:117. PubMed
  49. Adrover JM, et al. 2022. JCI Insight. 7:. PubMed
  50. Steubing RD, et al. 2022. Brain Behav Immun Health. 24:100493. PubMed
  51. Lu H, et al. 2021. Autophagy. 17:2511. PubMed
  52. Kawashima N, et al. 2022. Nat Commun. 13:1624. PubMed
  53. Zhu S, et al. 2022. Front Pharmacol. 13:996635. PubMed
  54. Palacios LM, et al. 2022. Biology (Basel). 11:. PubMed
  55. Radovanovic I, et al. 2014. J Immunol. 193:1290. PubMed
  56. Evans H, et al. 2015. J Immunol. 195: 2973 - 2984. PubMed
  57. Cardona S, et al. 2015. ASN Neuro. 7: 1759091415608204. PubMed
  58. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  59. Uzhachenko RV, et al. 2021. Cell Reports. 35(1):108944. PubMed
  60. Han Y, et al. 2020. Nat Commun. 11:1776. PubMed
  61. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  62. Haertel E, et al. 2018. Eur J Immunol. 48:1001. PubMed
  63. Tordesillas L, et al. 2018. Nat Commun. 9:5238. PubMed
  64. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  65. Bowers E, et al. 2018. Nat Med. 24:95. PubMed
  66. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  67. Biswas S, et al. 2021. Nature. 591:464. PubMed
  68. Forte E, et al. 2020. J Cell Mol Med. . PubMed
  69. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  70. Ganeshan K et al. 2019. Cell. 177(2):399-413 . PubMed
  71. Wiley CD, et al. 2019. JCI Insight. 4:e130056. PubMed
  72. Krasteva G, et al. 2011. Proc Natl Acad Sci U S A. 108:9478. PubMed
  73. Yoon Y, et al. 2021. Cancers (Basel). 13: . PubMed
  74. Shi S, et al. 2020. Clin Cancer Res. 26:5990. PubMed
  75. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  76. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  77. Yang W, et al. 2020. Mucosal Immunol. 13:788. PubMed
  78. Jung BG, et al. 2022. PLoS Pathog. 18:e1010454. PubMed
  79. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  80. Shibata K, et al. 2014. J Immunol. 192:2210. PubMed
  81. Mantia-Smaldone G, et al. 2014. Gynecol Oncol. 133:584. PubMed
  82. Rybalko V, et al. 2015. PLoS One. 10: 0145550. PubMed
  83. AR P, et al. 2016. Circ Res. 118: 400-409. PubMed
  84. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  85. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  86. Jtte BB, et al. 2021. iScience. 24(8):102833. PubMed
  87. Uroda T, et al. 2020. Nat Protoc. 15:2107. PubMed
  88. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  89. Huang B, et al. 2020. Cell. 179(5):1160-1176.e24.. PubMed
  90. Ning F, et al. 2019. J Exp Med. 216:1396. PubMed
  91. Higashi AY, et al. 2019. J Am Soc Nephrol. 30:80. PubMed
  92. Lyons J, et al. 2018. Sci Signal. 11. PubMed
  93. Evans R, et al. 2019. Cell Rep. 27:1967. PubMed
  94. Hammond TR, et al. 2019. Immunity. 50:253. PubMed
  95. Schönfeld M, et al. 2021. Alcohol Clin Exp Res. 45:1980. PubMed
  96. Bhattacherjee A, et al. 2021. Mol Neurodegener. 16:19. PubMed
  97. Bagayoko S, et al. 2021. PLoS Pathog. 17:e1009927. PubMed
  98. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  99. Marangoni F, et al. 2021. Cell. . PubMed
  100. Wang LT, et al. 2021. STAR Protocols. 2(1):100337. PubMed
  101. Fachi JL, et al. 2020. J Exp Med. 217:00:00. PubMed
  102. Chew W, et al. 2016. Nat Methods. 13: 868-874. PubMed
  103. Cordeiro O, et al. 2016. PLoS One. 11: 0151848. PubMed
  104. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  105. Commerford CD et al. 2018. Cell reports. . PubMed
  106. Zeng J, et al. 2019. Cell Rep. 27:549. PubMed
  107. Yousef H, et al. 2018. Bio Protoc. 8:22. PubMed
  108. Willingham SB, et al. 2018. Cancer Immunol Res. 6:1136. PubMed
  109. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  110. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  111. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  112. Liu H, et al. 2020. Cancer Cell. 37(3):324-339. PubMed
  113. Hillel–Karniel C, et al. 2020. Cell Reports. 30(3):807-819.e4.. PubMed
  114. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  115. Donlan AN, et al. 2020. Anaerobe. 66:102275. PubMed
  116. Uher O, et al. 2021. Cancers (Basel). 13:. PubMed
  117. Liu M, et al. 2020. Cell Rep. 32:107990. PubMed
  118. Jeljeli M, et al. 2020. Cell Rep. 33:108325. PubMed
  119. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  120. Chi Z, et al. 2020. Molecular Cell. 80(1):43-58.e7. PubMed
  121. Utz B, et al. 2020. Sci Rep. 10:18733. PubMed
  122. Chun E, et al. 2020. Immunity. 51(5):871-884.e6.. PubMed
  123. Bahar Halpern K, et al. 2020. Nat Commun. 11:1936. PubMed
  124. Soldevilla MM, et al. 2019. Mol Ther. 27:1878. PubMed
  125. Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
  126. Li Y, et al. 2019. Sci Rep. 9:6932. PubMed
  127. Mifflin L, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  128. Stewart JM, et al. 2020. ACS Biomater Sci Eng. 6:5941. PubMed
  129. Gao H, et al. 2021. Cells. 10:. PubMed
  130. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  131. Ajina R, et al. 2021. Cancer Immunol Res. 9:386. PubMed
  132. Frii J, et al. 2021. Immunity. 54(5):1002-1021.e10. PubMed
  133. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  134. Zhang X, et al. 2020. Elife. 9:00. PubMed
  135. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  136. Ayaub E,et al. 2017. Sci Rep.. 10.1038/s41598-017-13511-z. PubMed
  137. Peralta Ramos JM, et al. 2017. Front Immunol. 1.490277778. PubMed
  138. Halpern KB, et al. 2018. Nat Biotechnol. 36:962. PubMed
  139. Alikhanyan K, et al. 2021. Cancers (Basel). 13:. PubMed
  140. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  141. Ali M, et al. 2022. JCI Insight. 7:. PubMed
  142. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  143. Cho YK, et al. 2022. Nat Commun. 13:4084. PubMed
  144. Ghandhi SA, et al. 2022. Sci Rep. 12:14124. PubMed
  145. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  146. Veremeyko T, et al. 2012. J Vis Exp. 65: 4097. PubMed
  147. Fu H, et al. 2020. Front Immunol. 11:595813. PubMed
  148. Oladiran O, et al. 2021. J Neuroinflammation. 77:18. PubMed
  149. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  150. Chauveau A, et al. 2020. Immunity. 52:794. PubMed
  151. Haikala HM, et al. 2019. Nat Commun. 10:620. PubMed
  152. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  153. Neuhöfer P, et al. 2021. Nature. 597:715. PubMed
  154. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  155. Hum NR, et al. 2022. Front Oncol. 12:928474. PubMed
  156. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  157. Selvaraj UM, et al. 2021. Brain Behav Immun. 95:502. PubMed
  158. Ying T, et al. 2021. Am J Physiol Endocrinol Metab. 320:E1148. PubMed
  159. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  160. Momin N, et al. 2022. Nat Commun. 13:109. PubMed
  161. Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
  162. Pilones KA, et al. 2020. Cancer Immunol Res. 8:1054. PubMed
  163. Toubal A, et al. 2020. Nat Commun. 3755:11. PubMed
  164. McFarland AP, et al. 2021. Immunity. 54(6):1320-1337.e4. PubMed
  165. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  166. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  167. Martina M, et al. 2014. J Vis Exp. 87: 51192. PubMed
  168. Alikhanyan K, et al. 2020. Immun Inflamm Dis. 8:181. PubMed
  169. Cheng Y, et al. 2019. Clin Cancer Res. 25:2621. PubMed
  170. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  171. Yang Y, et al. 2022. Elife. 11:. PubMed
  172. Abramowski P, et al. 2014. J Neuroimmunol. 274:111. PubMed
  173. Hoeksema M, et al. 2015. J Immunol. 194:3909. PubMed
  174. Dhanwani R, et al. 2020. Sci Adv. 6:eaba3688. PubMed
  175. Tripathi H, et al. 2020. Stem Cell Rev Rep. 0.953472222. PubMed
  176. Cardenas JJ, et al. 2020. Methods Enzymol. 415:631. PubMed
  177. Kaya B, et al. 2020. Cell Reports. 32(5):107979. PubMed
  178. Sztwiertnia I, et al. 2020. PLoS One. 15:e0233789. PubMed
  179. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  180. Wang R, et al. 2022. Front Immunol. 13:947756. PubMed
  181. Becker W, et al. 2021. J Crohns Colitis. 15:1032. PubMed
  182. Galle-Treger L, et al. 2020. J Allergy Clin Immunol. 145:502. PubMed
  183. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  184. Clement CC, et al. 2021. Nat Commun. 12:4447. PubMed
  185. Henrich IC, et al. 2021. Cancer Res. 81:2171. PubMed
  186. Li H, et al. 2021. Adv Sci (Weinh). 2001596:8. PubMed
  187. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  188. Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
  189. Gierut J, et al. 2015. Stem Cell Res. 15: 165-171. PubMed
  190. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  191. Haka A, et al. 2012. PLoS One. 7:e44823. PubMed
  192. Veremeyko T, et al. 2019. J Neurosci Res. 97:162. PubMed
  193. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
  194. Kim MY, et al. 2018. Cell. 173:1439. PubMed
  195. Camara A, et al. 2019. Immunity. 50:1467. PubMed
  196. Michaelis KA, et al. 2019. Brain Behav Immun. 82:338. PubMed
  197. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  198. Xu Q, et al. 2021. Theranostics. 11:1937. PubMed
  199. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  200. Zhang R, et al. 2022. Front Pharmacol. 13:870848. PubMed
  201. Yu W, et al. 2022. Nat Commun. 13:3544. PubMed
  202. Li D, et al. 2022. Emerg Microbes Infect. 11:2248. PubMed
  203. Huetter J, et al. 2020. Cancer Immunol Res. 0.954861111. PubMed
  204. Favuzzi E, et al. 2021. Cell. 184(15):4048-4063.e32. PubMed
  205. DiToro D, et al. 2020. Immunity. 650:52. PubMed
  206. Draper D, et al. 2012. J Immunol. 188:5327. PubMed
  207. Hohsfield LA, et al. 2020. J Neuroinflammation. 0.902083333. PubMed
  208. Godwin MS, et al. 2019. JCI Insight. 4:e126070. PubMed
  209. Yuan X, et al. 2017. Elife. 6:e29540. PubMed
  210. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  211. Selvaraj UM et al. 2018. Endocrinology. 159(11):3848-3859 . PubMed
  212. Pinho–Ribeiro FA, et al. 2018. Cell. 173:1083. PubMed
  213. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  214. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  215. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  216. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  217. Wang X, et al. 2022. Front Immunol. 13:864984. PubMed
  218. Galani IE, et al. 2022. STAR Protoc. 3:101151. PubMed
  219. Abdelfattah N, et al. 2022. Nat Commun. 13:767. PubMed
  220. Ou YC, et al. 2020. ACS Nano. 1.035416667. PubMed
  221. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  222. Zelco A, et al. 2020. Front Cell Neurosci. 0.75625. PubMed
  223. Wang LT, et al. 2020. Cell Rep. 32:108188. PubMed
  224. Hadas R, et al. 2020. JCI Insight. 5:00. PubMed
  225. Stock M, et al. 2015. Osteoarthritis Cartilage. 23: 1221-1225. PubMed
  226. Wakabayashi T et al. 2018. Cell stem cell. 22(3):384-397 . PubMed
  227. Kaiser T, et al. 2019. Eneuro. 6. PubMed
  228. El Agha E, et al. 2017. Cell Stem Cell. 1.014583333. PubMed
  229. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  230. Ben-Moshe S, et al. 2019. Nat Metab. 1:899. PubMed
  231. Bhatt D, et al. 2021. J Exp Med. 218:. PubMed
  232. Lu Z, et al. 2021. J Clin Invest. 131:. PubMed
  233. Luo M, et al. 2021. J Immunol. 207:1683. PubMed
  234. Martina M, et al. 2016. J Am Soc Nephrol. 27: 1113-1123. PubMed
  235. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  236. Yu L, et al. 2020. Nat Commun. 2.045833333. PubMed
  237. Liu X, et al. 2019. Mol Cancer Ther. 18:706. PubMed
  238. Ji L et al. 2019. Immunity. 51(2):272-284 . PubMed
  239. Jiang P, et al. 2018. Nat Med. 24:1550. PubMed
  240. Wang X, et al. 2018. Nat Commun. 9:551. PubMed
  241. Li N, et al. 2022. Nat Commun. 13:7281. PubMed
  242. Pedicone C, et al. 2022. iScience. 25:104170. PubMed
  243. Godwin MS, et al. 2021. Am J Physiol Lung Cell Mol Physiol. 320:L393. PubMed
  244. Reda M, et al. 2022. Nat Commun. 13:4261. PubMed
  245. Li Y, et al. 2022. STAR Protoc. 3:101364. PubMed
  246. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  247. Milich LM, et al. 2021. J Exp Med. 218:. PubMed
  248. Kline JM, et al. 2021. J Biol Chem. :100373. PubMed
  249. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  250. Starikova E, et al. 2021. Front Pharmacol. 12:667572. PubMed
  251. Klein S, et al. 2016. J Cell Sci. 129: 2573 - 2585. PubMed
  252. Armaka M, et al. 2018. Nat Commun. 9:618. PubMed
  253. Lang JF et al. 2019. Nat Commun. 10(1):3415 . PubMed
  254. Theurich S et al. 2017. Cell metabolism. 26(1):171-184 . PubMed
  255. Martin A, et al. 2018. Oncotarget. 9:28364. PubMed
  256. Zhao Y, et al. 2020. Front Immunol. 2.572222222. PubMed
  257. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  258. Ireland L, et al. 2020. Front Immunol. 11:297. PubMed
  259. Gago-Lopez N, et al. 2019. EMBO Mol Med. 11:e10697. PubMed
  260. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  261. Uluçkan ö, et al. 2020. Cell Reports. 29(4):844-859.e3.. PubMed
  262. Morein D, et al. 2021. Cells. 10: . PubMed
  263. Yan C, et al. 2022. NPJ Precis Oncol. 6:6. PubMed
  264. Phansalkar R, et al. 2021. Elife. 10:. PubMed
  265. Kim S, et al. 2022. Cancers (Basel). 14:. PubMed
  266. Yoldi G, et al. 2016. Cancer Res . 76: 5857 - 5869. PubMed
  267. Ling Y, et al. 2016. Pharmacol Res. S1043-6618(16)31329-9. PubMed
  268. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  269. Lu C, et al. 2020. Cancer Cell. 39(1):96-108.e6. PubMed
  270. Yang C, et al. 2020. Cell Host Microbe. 467:27. PubMed
  271. Willemze RA, et al. 2019. Mol Med. 25:01:00. PubMed
  272. Fransén Pettersson N, et al. 2018. PLoS One. 13:e0203228. PubMed
  273. Winter C, et al. 2018. Cell Metab. 28:175. PubMed
  274. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  275. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  276. Wang Y, et al. 2022. Nat Commun. 13:1454. PubMed
  277. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  278. Zhang X, et al. 2022. J Exp Clin Cancer Res. 41:246. PubMed
  279. Guan D, et al. 2021. Cell Death Dis. 12:431. PubMed
  280. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  281. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  282. Wang J, et al. 2021. Am J Cancer Res. 11:2005. PubMed
  283. Wang X, et al. 2021. Theranostics. 11:209. PubMed
  284. Liu SS, et al. 2021. Immunity. :. PubMed
  285. Ukidve A, et al. 2020. Proc Natl Acad Sci U S A. 117:17727. PubMed
  286. E O’Koren, R Mathew, D Saban 2016. Sci Rep. 6:20636. PubMed
  287. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  288. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  289. Seeling M, et al. 2013. Proc Natl Acad Sci U S A. 110:10729. PubMed
  290. Petriello MC, et al. 2018. Toxicol Sci. 162:548. PubMed
  291. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
  292. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  293. Forte E, et al. 2020. Cell Rep. 30:3149. PubMed
  294. Wang J, et al. 2020. J Hematol Oncol. 0.610416667. PubMed
  295. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  296. Cong L, et al. 2021. Breast Cancer Res. 23:51. PubMed
  297. De Micheli AJ, et al. 2020. Am J Physiol Cell Physiol. 319:C885. PubMed
  298. Sibler E, et al. 2021. Cells. 10:. PubMed
  299. Oladiran O, et al. 2021. Front Immunol. 12:720733. PubMed
  300. Schäfer AL, et al. 2021. Front Immunol. 12:696810. PubMed
  301. Sebastian A, et al. 2021. Cells. 10:. PubMed
  302. Kerdidani D, et al. 2022. J Exp Med. 219:. PubMed
  303. Lux A, et al. 2014. Cell Rep. 10:236. PubMed
  304. Madsen P, et al. 2016. J Neurosci. 36: 5128 - 5143. PubMed
  305. Fox B, et al. 2016. PLoS One. 12: 1006189. PubMed
  306. Parker K, Horn L, Ostrand-Rosenberg S 2016. J Leukoc Biol. 100: 463 - 470.. PubMed
  307. Chen MB, et al. 2020. Cell Rep. 30:4418. PubMed
  308. Dinh HQ, et al. 2020. Immunity. 53(2):319-334.e6. PubMed
  309. Wang J, et al. 2020. Cell. 183(7):1867-1883.e26. PubMed
  310. Deniset JF et al. 2019. Immunity. 51(1):131-140 . PubMed
  311. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  312. Lee S, et al. 2021. Autophagy. 18:1062. PubMed
  313. Swanson WB, et al. 2021. Biomaterials. 272:120769. PubMed
  314. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
  315. Sun D, et al. 2020. PLoS Pathog. 16:e1008361. PubMed
  316. Zhu Q, et al. 2021. J Am Heart Assoc. 10:e023491. PubMed
  317. Amend A, et al. 2021. Int J Mol Sci. 22:. PubMed
  318. Parent AV, et al. 2021. Cell Reports. 36(7):109538. PubMed
  319. Ito Y, et al. 2021. Cell Reports. 35(4):109052. PubMed
  320. Ma Y, et al. 2021. Developmental Cell. 56(4):478-493.e11. PubMed
  321. Ye Y, et al. 2020. Genome Med. 0.557638889. PubMed
  322. Campisi L, et al. 2016. Nat Immunol. 10.1038/ni.3512. PubMed
  323. Holzapfel B, et al. 2015. Biomaterials. 61: 103-114. PubMed
RRID
AB_312980 (BioLegend Cat. No. 103115)
AB_312981 (BioLegend Cat. No. 103116)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
CD45
Specificity Alt (DOES NOT SHOW ON TDS):
CD45
App Abbreviation (DOES NOT SHOW ON TDS):
FC
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS UV™ 395 anti-mouse CD45 30-F11 FC
Go To Top Version: 3    Revision Date: 01-30-2019

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account