Loading...

APC anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
30-F11_APC_090507
C57BL/6 mouse splenocytes stained with 30-F11 APC
  • 30-F11_APC_090507
    C57BL/6 mouse splenocytes stained with 30-F11 APC
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
103111 25 µg 27€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
103112 100 µg 76€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Jiang Z, et al. 2021. J Clin Invest. 131: . PubMed
  2. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  3. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  4. Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
  5. Nigam S, et al. 2020. Mol Imaging Biol. 22:685. PubMed
  6. Yang D, et al. 2022. Cell. 185:1905. PubMed
  7. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  8. Gavin KM, et al. 2018. Front Endocrinol (Lausanne). 9:276. PubMed
  9. Wang L, et al. 2018. Bone Res. 6:22. PubMed
  10. Cha JH et al. 2018. Molecular cell. 71(4):606-620 . PubMed
  11. Haimon Z et al. 2018. Nature immunology. 19(6):636-644 . PubMed
  12. Ying W, et al. 2019. Cell Metab. 29:457. PubMed
  13. Strickley JD, et al. 2019. Nature. 575:519. PubMed
  14. Bouchareychas L, et al. 2021. iScience. 24(8):102847. PubMed
  15. Almada AE, et al. 2021. Cell Reports. 34(4):108656. PubMed
  16. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  17. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  18. Jaiswal AK, et al. 2020. Immunobiology. 225:151956. PubMed
  19. Cayre S, et al. 2020. Development. 147:00:00. PubMed
  20. Díaz NM, et al. 2020. Invest Ophthalmol Vis Sci. 61:37:00. PubMed
  21. Mourao L, et al. 2019. Sci Rep. 0.991666667. PubMed
  22. Oetjen LK et al. 2017. Cell. 171(1):217-228 . PubMed
  23. Testini C, et al. 2019. EMBO Rep. 20:e47845. PubMed
  24. Gao Q, et al. 2019. J Exp Med. 216:688. PubMed
  25. Shavit Stein E, et al. 2018. Neural Plast. 2018:7692182. PubMed
  26. Ahmed M, et al. 2016. Development. 143: 1663 - 1673. PubMed
  27. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  28. Lim JT, et al. 2020. Mol Cancer Ther. 1809:19. PubMed
  29. Rosa FF, et al. 2020. Bio Protoc. 10:e3619. PubMed
  30. Wang Y, et al. 2021. J Bone Oncol. 30:100386. PubMed
  31. Lu L, et al. 2022. Sci Rep. 12:931. PubMed
  32. Parhiz H, et al. 2022. J Control Release. 344:50. PubMed
  33. Karlen SJ, et al. 2018. J Neuroinflammation. 15:344. PubMed
  34. Du Q, et al. 2019. Front Microbiol. 10:2050. PubMed
  35. Kang I, et al. 2012. Blood. 119:3295. PubMed
  36. Yanagida K, et al. 2020. Dev Cell. 779:52. PubMed
  37. Hirano KI, et al. 2021. eLife. 0.416666666666667. PubMed
  38. Larouche JA, et al. 2021. eLife. 0.416666666666667. PubMed
  39. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  40. Barberio AE, et al. 2020. ACS Nano. 14:11238. PubMed
  41. Chiche A, et al. 2016. Oncogene. 10.1038/onc.2016.396. PubMed
  42. Eastman A, et al. 2016. J Immunol . 194: 5999-6010. PubMed
  43. Chen J, et al. 2022. Nat Commun. 13:6759. PubMed
  44. Wang S, et al. 2022. Front Immunol. 13:869061. PubMed
  45. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  46. Barwe SP, et al. 2022. J Clin Med. 11:. PubMed
  47. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  48. Yu X, et al. 2021. Nature. 594:560. PubMed
  49. Sato S, et al. 2021. Int J Mol Sci. 22:. PubMed
  50. Oliva Chávez AS, et al. 2021. Nat Commun. 12:3696. PubMed
  51. Engelbrecht E, et al. 2020. eLife. 9:e52690.. PubMed
  52. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  53. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  54. Strunz M, et al. 2020. Nat Commun. 2.929861111. PubMed
  55. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  56. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  57. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  58. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  59. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  60. Motoyama S, et al. 2020. Cells. :9. PubMed
  61. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  62. Romagnoli M, et al. 2020. Development. 147:. PubMed
  63. Li Q, et al. 2021. Brain Behav Immun. 94:437. PubMed
  64. Wang X, et al. 2022. Nat Aging. 2:155. PubMed
  65. Wang T, et al. 2020. Blood Sci. 2:79. PubMed
  66. Jin X, et al. 2019. Mol Cell. 73:22:00. PubMed
  67. Duarte N, et al. 2018. Hepatol Commun. 0.833333333. PubMed
  68. Lv H, et al. 2020. Cell Metabolism. 33(1):110-127.e5. PubMed
  69. Amouyal C, et al. 2020. EBioMedicine. 58:102895. PubMed
  70. Liu L, et al. 2015. Neurol Neuroimmunol Neuroinflamm. 2: 174. PubMed
  71. Hyatt L, et al. 2014. PLoS One. 9:109072. PubMed
  72. Mauduit O, et al. 2022. Front Immunol. 13:1011125. PubMed
  73. Chen Z, et al. 2022. Theranostics. 12:6242. PubMed
  74. Xu X, et al. 2021. J Nanobiotechnology. 19:376. PubMed
  75. Bourn JR, et al. 2021. Cancer Lett. 503:75. PubMed
  76. Khateb M, et al. 2022. Cell Rep. 40:111219. PubMed
  77. Xu Q, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  78. Liu K, et al. 2022. Theranostics. 12:639. PubMed
  79. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  80. Pelletier A, et al. 2012. J Immunol. 188:5561. PubMed
  81. Herting CJ, et al. 2019. Brain. 142:3834. PubMed
  82. Romagnoli M, et al. 2019. Stem Cell Reports. 1.077083333. PubMed
  83. Ning X, et al. 2019. Mol Cell. 74:19. PubMed
  84. De S, et al. 2018. Development. 145. PubMed
  85. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  86. Lafkas D, et al. 2013. J Cell Biol. 203:47. PubMed
  87. Ma S, et al. 2021. Cell Reports. 34(6):108726. PubMed
  88. Ankawa R, et al. 2021. Developmental Cell. . PubMed
  89. Hu EY, et al. 2021. Blood Adv. 5:3152. PubMed
  90. Palathingal Bava E, et al. 2022. JCI Insight. 7:. PubMed
  91. An J,et al. 2017. Sci Rep.. 10.1038/s41598-017-13629-0. PubMed
  92. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  93. Maston LD, et al. 2017. Am J Physiol Lung Cell Mol Physiol. 312:L609. PubMed
  94. Bresson L, et al. 2018. Development. 145. PubMed
  95. Charmsaz S, et al. 2017. Leukemia. 31:1779. PubMed
  96. Sambasivan R, et al. 2011. Development. 138:3647. PubMed
  97. Frii J, et al. 2021. Immunity. 54(5):1002-1021.e10. PubMed
  98. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  99. Fischer A, et al. 2022. Nat Immunol. 23:518. PubMed
  100. Hu J, et al. 2022. Cell Mol Neurobiol. . PubMed
  101. Chen L, et al. 2021. Cell Death Differ. 28:1880. PubMed
  102. Shcherbina A, et al. 2020. Cell Rep. 32:107964. PubMed
  103. Wu J, et al. 2020. Immunity. 53:115. PubMed
  104. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
  105. Xiao P, et al. 2019. J Exp Med. 216:337. PubMed
  106. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  107. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  108. Zheng B, et al. 2018. J Hematol Oncol. 11:16. PubMed
  109. Pal B, et al. 2017. Nat Commun.. 10.1038/s41467-017-01560-x. PubMed
  110. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  111. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  112. Hanasoge Somasundara AV, et al. 2021. Cell Rep. 37:110099. PubMed
  113. Thinard R, et al. 2022. Pharmaceutics. 14:. PubMed
  114. Yang H, et al. 2022. Nutrients. 14:. PubMed
  115. Hu J, et al. 2022. J Neuroinflammation. 19:71. PubMed
  116. Pezoldt J, et al. 2022. Nat Commun. 13:7227. PubMed
  117. Yuan Z, et al. 2018. Emerg Microbes Infect. 7:59. PubMed
  118. Hou M, et al. 2020. Stem Cell Res Ther. 11:55. PubMed
  119. Jia Q, et al. 2021. Theranostics. 4699:11. PubMed
  120. Paiva-Oliveira E, et al. 2017. Histochem Cell Biol. 10.1007/s00418-017-1556-6. PubMed
  121. Crooks SD, et al. 2022. Immunohorizons. 6:705. PubMed
  122. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  123. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  124. Koren E, et al. 2022. Nat Commun. 13:4628. PubMed
  125. Bauer T, et al. 2021. Life (Basel). 11:. PubMed
  126. Li P, et al. 2022. EMBO Mol Med. 14:e14511. PubMed
  127. Zuo S, et al. 2021. J Immunother Cancer. 9:. PubMed
  128. Myerson JW, et al. 2021. Nat Nanotechnol. Online ahead of print. PubMed
  129. Dudek KA, et al. 2020. Proc Natl Acad Sci U S A. 117:3326. PubMed
  130. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  131. Wang C, et al. 2011. Hepatology. 55:108. PubMed
  132. Sim S, et al. 2016. PLoS One. 11: 0152485. PubMed
  133. Mangum L, et al. 2016. Toxicol Sci. 150: 169 - 177. PubMed
  134. Mizuno T, et al. 2017. Sci Rep. 7:42714. PubMed
  135. Nosho S, et al. 2020. Int J Mol Sci. 21:00. PubMed
  136. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  137. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  138. Yang Y, et al. 2022. Elife. 11:. PubMed
  139. Dey S, et al. 2020. J Immunother Cancer. 8:. PubMed
  140. Zhang Q, et al. 2022. Nat Commun. 13:2406. PubMed
  141. Scur M, et al. 2022. Nat Commun. 13:7272. PubMed
  142. Kaur A, et al. 2019. Cancer Discov. 9:64. PubMed
  143. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  144. Zhou G, et al. 2019. FASEB J. 33:11396. PubMed
  145. Xi W, et al. 2021. Stem Cell Res Ther. 167:12. PubMed
  146. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  147. Dawson CA, et al. 2021. Nature Protocols. 16(4):1907-1935. PubMed
  148. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  149. Limbad C, et al. 2022. iScience. 25:103848. PubMed
  150. Chiang HY, et al. 2022. Nat Commun. 13:874. PubMed
  151. Aguilera M, et al. 2021. Int J Mol Sci. 22:. PubMed
  152. Yamada KJ, et al. 2020. PLoS Pathog. 16:e1008354. PubMed
  153. Tu WL, et al. 2018. Am J Pathol. 188:2688. PubMed
  154. Chiche A, et al. 2019. Breast Cancer Res. 21:13. PubMed
  155. Feng J,et al. 2017. Nat Commun. . 10.1038/s41467-017-01056-8. PubMed
  156. Garcia-Bonilla L, et al. 2014. J Immunol. 193:2531. PubMed
  157. Ding X, et al. 2015. J Immunol. 194:4251. PubMed
  158. Wang L, et al. 2015. Cancer Immunol Res. 3: 1030-1041. PubMed
  159. Mueller A, et al. 2016. Nature. 540:276-279. PubMed
  160. Perry JL, et al. 2020. ACS Nano. 5.583333333. PubMed
  161. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  162. Penkert RR, et al. 2020. Obesity (Silver Spring). 1631:28. PubMed
  163. Mori A, et al. 2021. Cells. :10. PubMed
  164. Dion-Albert L, et al. 2022. Nat Commun. 13:164. PubMed
  165. Long JT, et al. 2022. Elife. 11:. PubMed
  166. Zhang Z, et al. 2021. Exp Dermatol. 30:102. PubMed
  167. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  168. Echevarría-Vargas IM, et al. 2018. EMBO Mol Med. 10:e8446. PubMed
  169. Shi R, et al. 2019. J Cancer. 10:367. PubMed
  170. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  171. Usmani SM et al. 2019. Cell host & microbe. 25(1):73-86 . PubMed
  172. Zasłona Z, et al. 2017. Am J Physiol Lung Cell Mol Physiol. 312:L855. PubMed
  173. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  174. Liu D, et al. 2020. Front Pharmacol. 11:204. PubMed
  175. Yang Y, et al. 2021. Cell Reports. 34(10):108822. PubMed
  176. Taya M, et al. 2020. Endocr Relat Cancer. 27:261. PubMed
  177. Saber M, et al. 2021. J Neurosci Res. 99:1136. PubMed
  178. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  179. Murdock BJ, et al. 2021. JCI Insight. 6:. PubMed
  180. Cai B, et al. 2020. Cell Metabolism. 31(2):406-421.e7.. PubMed
  181. Lu Y, et al. 2020. Immunity. 52:782. PubMed
  182. Toyama K, et al. 2018. Arterioscler Thromb Vasc Biol. 38:1392. PubMed
  183. Qiao S, et al. 2019. J Neuroinflammation. 16:4. PubMed
  184. Elias S, et al. 2015. PLoS Biol. 13:1002142. PubMed
  185. Deng P, et al. 2021. Cell Stem Cell. 28(6):1057-1073.e7. PubMed
  186. Zhang J, et al. 2022. Biomater Res. 26:44. PubMed
  187. Hoover AR, et al. 2022. Clin Transl Med. 12:e937. PubMed
  188. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  189. Carmody C et al. 2019. Endocrinology. 160(5):1205-1222 . PubMed
  190. Fu NY, et al. 2018. Dev Cell. 47:629. PubMed
  191. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  192. Yeo SK, et al. 2020. eLife. 9:e58810.. PubMed
  193. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  194. Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
  195. Nasser H, et al. 2020. Cell Death Discov. 0.29375. PubMed
  196. Sroor HM, et al. 2019. Sci Rep. 9:20217. PubMed
  197. Chen PY, et al. 2019. Nat Metab. 0.675. PubMed
  198. Cao Y, et al. 2019. Nat Commun. 10:1280. PubMed
  199. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  200. Zhang T, et al. 2020. JCI Insight. 5:00. PubMed
  201. Cai T, et al. 2022. Nat Commun. 13:2228. PubMed
  202. Kim KS, et al. 2022. JCI Insight. 7:. PubMed
  203. Porrello A, et al. 2018. Nat Commun. 9:1988. PubMed
  204. Saber M, et al. 2020. Eur J Neurosci. 52:2791. PubMed
  205. Vaas M, et al. 2016. J Cereb Blood Flow Metab. 10.1177/0271678X16676825. PubMed
  206. Wong J, et al. 2016. Sci Signal. 9: ra103. PubMed
  207. Yuan Z, et al. 2016. J Virol. 90: 7728 - 7739. PubMed
  208. Garcia-Bonilla L, et al. 2015. J Neurosci. 35: 14783 - 14793. PubMed
  209. Jiang Y, et al. 2015. MBio. 6: e01426-15. PubMed
  210. Roberts L, et al. 2014. Infect Immun . 82:2504. PubMed
  211. Gopalakrishnapillai A, et al. 2021. Cancers (Basel). 13:. PubMed
  212. Liu G, et al. 2022. Theranostics. 12:2248. PubMed
  213. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  214. Arora S, et al. 2021. Med (N Y). 2:938. PubMed
  215. Li H, et al. 2022. iScience. 25:104481. PubMed
  216. Cayre S, et al. 2020. Development. . PubMed
  217. Endo-Umeda K, et al. 2021. Sci Rep. 11:22595. PubMed
  218. Pal B, et al. 2021. Breast Cancer Res. 23:69. PubMed
  219. Maller O, et al. 2020. Nat Mater. 20:548. PubMed
  220. Ortiz A, et al. 2019. Cancer Cell. 35:33:00. PubMed
  221. Ouadah Y, et al. 2019. Cell. 179:403. PubMed
  222. Piotrowski AF, et al. 2018. Oncoimmunology. 7:e1445951. PubMed
  223. Sarshad AA, et al. 2018. Mol Cell. 71:1040. PubMed
  224. Jaeger N, et al. 2020. Cell Rep. 33:108331. PubMed
  225. Koh BI, et al. 2020. Nat Commun. 3.143055556. PubMed
  226. Ren D, et al. 2020. Am J Cancer Res. 2851:10. PubMed
  227. Hu Y, et al. 2021. J Nanobiotechnology. 19:416. PubMed
  228. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  229. Su M, et al. 2018. Immunol Cell Biol. 9:2448. PubMed
  230. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  231. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  232. Qu Y, et al. 2020. Cell Reports. 32(1):107873. PubMed
  233. Dai B, et al. 2021. Cell Reports Medicine. 2(8):100381. PubMed
  234. Bravo JI, et al. 2021. STAR Protocols. 2(2):100406. PubMed
  235. Chng S, et al. 2016. Sci Rep. 6: 23820. PubMed
  236. Quijano-Rubio A, et al. 2022. Nat Biotechnol. Online ahead of print. PubMed
  237. Scheyltjens I, et al. 2022. Nat Protoc. 17:2354. PubMed
  238. Liu C, et al. 2022. Nat Commun. 13:1989. PubMed
  239. Saber M, et al. 2021. J Neurotrauma. 38:2862. PubMed
  240. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  241. Okubo A, et al. 2021. Int J Mol Sci. 23:. PubMed
  242. Deets KA, et al. 2021. Elife. 10:. PubMed
  243. Murray CW, et al. 2022. Nat Commun. 13:1090. PubMed
  244. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  245. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  246. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  247. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
RRID
AB_312976 (BioLegend Cat. No. 103111)
AB_312977 (BioLegend Cat. No. 103112)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05-14-2013

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • APC anti-mouse CD45

  • Biotin anti-mouse CD45

  • FITC anti-mouse CD45

  • PE anti-mouse CD45

  • PE/Cyanine5 anti-mouse CD45

  • Purified anti-mouse CD45

  • PE/Cyanine7 anti-mouse CD45

  • APC/Cyanine7 anti-mouse CD45

  • Alexa Fluor® 488 anti-mouse CD45

  • Alexa Fluor® 647 anti-mouse CD45

  • Pacific Blue™ anti-mouse CD45

  • Alexa Fluor® 700 anti-mouse CD45

  • PerCP/Cyanine5.5 anti-mouse CD45

  • PerCP anti-mouse CD45

  • Alexa Fluor® 594 anti-mouse CD45

  • Brilliant Violet 421™ anti-mouse CD45

  • Brilliant Violet 570™ anti-mouse CD45

  • Brilliant Violet 510™ anti-mouse CD45

  • Brilliant Violet 605™ anti-mouse CD45

  • Purified anti-mouse CD45 (Maxpar® Ready)

  • PE/Dazzle™ 594 anti-mouse CD45

  • Brilliant Violet 711™ anti-mouse CD45

  • Brilliant Violet 785™ anti-mouse CD45

  • Brilliant Violet 650™ anti-mouse CD45

  • APC/Fire™ 750 anti-mouse CD45

  • Brilliant Violet 750™ anti-mouse CD45

  • TotalSeq™-A0096 anti-mouse CD45

  • TotalSeq™-B0096 anti-mouse CD45

  • Ultra-LEAF™ Purified anti-mouse CD45

  • Spark Blue™ 550 anti-mouse CD45

  • Spark NIR™ 685 anti-mouse CD45

  • TotalSeq™-C0096 anti-mouse CD45

  • Spark YG™ 570 anti-mouse CD45

  • PE/Fire™ 640 anti-mouse CD45

  • APC/Fire™ 810 anti-mouse CD45

  • PE/Fire™ 700 anti-mouse CD45

  • Spark Violet™ 538 anti-mouse CD45

  • Spark YG™ 593 anti-mouse CD45

  • Spark Blue™ 574 anti-mouse CD45 Antibody

  • Spark UV™ 387 anti-mouse CD45
ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account