Purified anti-human CD120b Antibody

Pricing & Availability
3G7A02 (See other available formats)
Regulatory Status
Other Names
Rat IgG2a, κ
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Product Citations
Human peripheral blood lymphocytes were stained with purified anti-human CD120b (clone 3G7A02) (filled histogram) or rat IgG2a, κ isotype control (open histogram), followed by biotinylated anti-rat IgG and Sav-PE.
  • 3G7A02_Purified_CD120b_Antibody_FC_051413
    Human peripheral blood lymphocytes were stained with purified anti-human CD120b (clone 3G7A02) (filled histogram) or rat IgG2a, κ isotype control (open histogram), followed by biotinylated anti-rat IgG and Sav-PE.
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358402 100 µg 90€
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CD120b, also known as TNFRII or TNFRSF1B, belongs to the TNF receptor superfamily and can interact with ligands TNF-α and TNF-β (also known as LT-α). It is a 75 kD type I transmembrane protein expressed on lymphocytes, monocytes, and granulocytes. When present in a heterocomplex with CD120a, it induces the recruitment of anti-apoptotic molecules, c-IAP1 and c-IAP2 that possess E3 ubiquitin ligase activity. Mutations in CD120b are associated with TNF-associated periodic syndrome (TRAPS) or periodic fever syndrome.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Partial CD120b recombinant protein expressed in 293E cells (22-211aa).
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Minshawi F, et al. 2019. Sci Rep. 0.509027778. PubMed
  2. De Maeyer RPH, et al. 2020. Nat Immunol. 21:615. PubMed
AB_2562150 (BioLegend Cat. No. 358402)

Antigen Details

75 kD, type I transmembrane protein, member of the TNF-receptor superfamily, forms a heterocomplex with TNFRI

Expressed on cells of hematopoietic lineage including monocytes, lymphocytes, and granulocytes

When complexed with TNFRI, recruits anti-apoptotic molecules c-IAP1 and c-IAP2 that possess ubiquitin ligase activity; cysteine rich extracellular region
Interacts with TTRAP and TRAF2
TNF-α and TNF-β (LT-α)
Cell Type
Granulocytes, Lymphocytes, Monocytes
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience, Transcription Factors
Molecular Family
CD Molecules
Antigen References

1. Andrews JS, et al. 1990. J. Immunol. 144:2582.
2. Nophar Y, et al. 1990. EMBO J. 9:3269.
3. Kohno T, et al. 1990. Proc. Natl. Acad. Sci. USA 87:8331.
4. Tartaglia LA, et al. 1991. Proc. Natl. Acad. Sci. USA 88:9292.
5. Hijdra D, et al. 2012. J. Inflamm. (Lond). 9:38.
6. Chen X, et al. 2013. J. Immunol. 190:1076.

Gene ID
7133 View all products for this Gene ID
View information about CD120b on UniProt.org

Related FAQs

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Go To Top Version: 1    Revision Date: 06/07/2013

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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