JNK BAX Bcl-2 Caspase 3 Caspase 8 Caspase 9 Caspase 8 Cytochrome-c DcR3 RcR3 DR4 DR5 Fas FasL TNF-a TRAIL TWEAK IkB JNK1 p50 p65 p53 PARP ACTIN JNK DcR1 DR3 NGF Caspase 7 Caspase 8 DAXX p75 Phosphotyrosine BID Apoptosis Through Death Receptors