Purified anti-rat CD11b/c Antibody

Pricing & Availability
OX-42 (See other available formats)
Regulatory Status
Other Names
Rat C3bi receptor, Rat CR3 complement receptor, ITGAM, ITGAX
Mouse IgG2a, κ
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Product Citations
LOU rat splenocytes were stained with APC anti-rat CD161 and anti-rat CD11b/c (clone OX-42) Purified (left) or Mouse IgG2a, κ isotype control (right) followed by FITC anti-mouse IgG.
  • OX-42_Purified_CD11b-c_Antibody_050219_updated.png
    LOU rat splenocytes were stained with APC anti-rat CD161 and anti-rat CD11b/c (clone OX-42) Purified (left) or Mouse IgG2a, κ isotype control (right) followed by FITC anti-mouse IgG.
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201801 100 µg 116 CHF
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The OX-42 antibody reacts with the CR3 complement (C3bi) receptor expressed on monocytes, granulocytes, macrophages, dendritic cells, and NK cells. This antibody appears to recognize a common epitope shared between CD11b and CD11c (integrin αM and αX chains). The OX-42 antibody precipitates three polypeptides with apparent molecular weights of 160, 103, and 95 kD, respectively. This antibody has been shown to block the formation of complement-mediated rosettes and leukocyte migration.

Product Details
Technical Data Sheet (pdf)

Product Details

Antibody Type
Host Species
Rat peritoneal macrophages.
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
IHC-F, IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections1,2, immunoprecipitation3, in vivo and in vitro blocking of C3bi binding3,4.

Application References

(PubMed link indicates BioLegend citation)
  1. Whiteland JL, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  2. Milligan CE, et al. 1991. J. Comp. Neurol. 314:125. (IHC)
  3. Robinson AP, et al. 1986. Immunology 57:239. (Block)
  4. Issekutz SE, et al. 1992. Immunology 76:655. (Block)
  5. Muehlbauer SM, et al. Am. J Pathol. 177:735. (FC) PubMed
  6. Thomas RA. et al. 2009. J Pharmacol Toxicol Methods. 60:263. PubMed
  7. Takeda Y, et al. 2011. Immunobiology. 216:1094. PubMed
  8. Furuhashi K, et al. 2013. J Am Soc Nephrol. PubMed
  9. Cheng HY, et al. 2013. Cytotherapy. 1465:608. PubMed
Product Citations
  1. Harms AS, et al. 2017. Acta Neuropathol Commun. 0.267361111. PubMed
  2. Beetz O, et al. 2019. PLoS One. 14:e0220546. PubMed
  3. Ibrahim A, et al. 2011. Diabetes. 60:1122. PubMed
AB_313989 (BioLegend Cat. No. 201801)

Antigen Details

Integrin family member

Monocytes, granulocytes, macrophages, dendritic cells

Receptor for C3bi
Complement C3bi
Cell Type
Dendritic cells, Granulocytes, Macrophages, Monocytes
Biology Area
Cell Biology, Complement, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Robinson AP, et al. 1986. Immunology 57:239.
2. Barcaly AN. 1981 Immunology 42:593.

Gene ID
25021 View all products for this Gene ID 499271 View all products for this Gene ID
View information about CD11b CD11c on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 05.02.2019

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-rat CD11b/c

  • FITC anti-rat CD11b/c

  • PE anti-rat CD11b/c

  • APC anti-rat CD11b/c

  • Biotin anti-rat CD11b/c

  • Alexa Fluor® 488 anti-rat CD11b/c

  • Alexa Fluor® 647 anti-rat CD11b/c

  • PerCP/Cyanine5.5 anti-rat CD11b/c

  • PE/Cyanine7 anti-rat CD11b/c


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