- S17015F (See other available formats)
- Regulatory Status
- Other Names
- HB7, T10, ADP-ribosyl cyclase
- Mouse IgG2a, κ
- Ave. Rating
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- Product Citations
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CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.Product Details
- Antibody Type
- Host Species
- Human CD38 transfectants
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with Spark YG™ 581 under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* Spark YG™ 581 has a maximum excitation of 562 nm and a maximum emission of 581 nm.
- Excitation Laser
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
S17015F is able to cross-block binding of clones HIT2 and HB-7 also raised against human CD38, but not S17015A based on in-house testing.
- Product Citations
AB_2890838 (BioLegend Cat. No. 397221)
AB_2890838 (BioLegend Cat. No. 397222)
- ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
T cells, B cells, NK, myeloid, plasma, and dendritic cells
- Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
- CD31, hyaluronic acid
- Cell Type
- B cells, Dendritic cells, NK cells, Plasma cells, T cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
- Ferrero E, et al. 1999. J Leuko Biol. 65:151.
- Lund F, et al. 1995. Immunol. Today 16:469.
- Gene ID
- 952 View all products for this Gene ID
- Specificity (DOES NOT SHOW ON TDS):
- Specificity Alt (DOES NOT SHOW ON TDS):
- View information about CD38 on UniProt.org
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