Purified anti-human Notch 2 Antibody

Pricing & Availability
MHN2-25 (See other available formats)
Regulatory Status
Other Names
Neurogenic locus notch homolog protein 2, hN2, fN2
Mouse IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
Human Notch2 transfected CHO cells stained with purified MHN2-25 conjugated to PE
  • MHN2-25_PE_data1_040810
    Human Notch2 transfected CHO cells stained with purified MHN2-25 conjugated to PE
  • MHN2-25_PE_data2_040810
    Human pre-B cell line NALM16 stained with MHN2-25 PE
Compare all formats
Cat # Size Price Quantity Check Availability Save
348301 25 µg $116
Check Availability

Need larger quantities of this item?
Request Bulk Quote

The Notch receptors are a type I transmembrane protein family that share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. They are highly conserved from invertebrates to mammals. Notch 1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors (Notch1-4).  Notch1 and Notch 2 are reported to be functionally redundant.  Notch 2 is expressed by Pre-B cells, double negative and CD8 single positive thymocytes, brain, lung cells. Notch 2 functions as a receptor for Jagged and Delta ligands, and may play a role in vascular, renal and hepatic development.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Reported Reactivity
African Green
Antibody Type
Host Species
Human Notch 2-human IgG1 Fc fusion protein
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Haraguchi K, et al. 2009. J. Immunol. 182:6168.
AB_10551623 (BioLegend Cat. No. 348301)

Antigen Details


Double negative and CD8 single positive thymocytes, pre-B cells, brain, lung

Jag 1, Jag 2; Delta 1, Delta 4
Cell Type
B cells, Neural Stem Cells, Thymocytes
Biology Area
Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells
Antigen References

1. Haraguchi K, et al. 2009. J. Immunol. 182:6168.
2. O’Neill CF, et al.2007. Am. J. Path. 171:1023.
3. Bertrand FE, et al. 2000. Leukemia 14:2095.

Gene ID
4853 View all products for this Gene ID
View information about Notch 2 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • APC anti-human Notch 2

  • Purified anti-human Notch 2

  • PE anti-human Notch 2

  • TotalSeq™-A1133 anti-human Notch 2 Antibody


Remember me
Forgot your password? Reset Password
Request an Account