PE anti-human Notch 2 Antibody

Pricing & Availability
MHN2-25 (See other available formats)
Regulatory Status
Other Names
Neurogenic locus notch homolog protein 2, hN2, fN2
Mouse IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
Human Notch 2 transfected CHO cells stained with MHN2-25 PE
  • MHN2-25_PE_data1_040810
    Human Notch 2 transfected CHO cells stained with MHN2-25 PE
  • MHN2-25_PE_data2_040810
    Human pre-B cell line NALM16 stained with MHN2-25 PE
Compare all formats See PE spectral data
Cat # Size Price Quantity Check Availability Save
348303 25 tests $149
Check Availability

Need larger quantities of this item?
Request Bulk Quote
348304 100 tests $325
Check Availability

Need larger quantities of this item?
Request Bulk Quote

The Notch receptors are a type I transmembrane protein family that share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. They are highly conserved from invertebrates to mammals. Notch 1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors (Notch1-4).  Notch1 and Notch 2 are reported to be functionally redundant.  Notch 2 is expressed by Pre-B cells, double negative and CD8 single positive thymocytes, brain, lung cells. Notch 2 functions as a receptor for Jagged and Delta ligands, and may play a role in vascular, renal and hepatic development.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Reported Reactivity
African Green
Antibody Type
Host Species
Human Notch 2-human IgG1 Fc fusion protein
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Haraguchi K, et al. 2009. J. Immunol. 182:6168.
AB_2153620 (BioLegend Cat. No. 348303)
AB_2153619 (BioLegend Cat. No. 348304)

Antigen Details


Double negative and CD8 single positive thymocytes, pre-B cells, brain, lung

Jag 1, Jag 2; Delta 1, Delta 4
Cell Type
B cells, Neural Stem Cells, Thymocytes
Biology Area
Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells
Antigen References

1. Haraguchi K, et al. 2009. J. Immunol. 182:6168.
2. O’Neill CF, et al.2007. Am. J. Path. 171:1023.
3. Bertrand FE, et al. 2000. Leukemia 14:2095.

Gene ID
4853 View all products for this Gene ID
View information about Notch 2 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


8999 BioLegend Way, San Diego, CA 92121
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • APC anti-human Notch 2

  • Purified anti-human Notch 2

  • PE anti-human Notch 2

  • TotalSeq™-A1133 anti-human Notch 2 Antibody


Remember me
Forgot your password? Reset Password
Request an Account