Analyte Specific Reagent. Analytical and performance characteristics are not established.
- 10.1 (See other available formats)
- VI MA36
- Other Names
- FcγRI, FcR I
- Mouse IgG1, κ
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- Product Citations
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CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).Product Details
- Human, Baboon, Capuchin Monkey, Chimpanzee, Cynomolgus, Rhesus, Squirrel Monkey
- Antibody Type
- Host Species
- Human rheumatoid synovial fluid cells and fibronectin-purified monocytes.
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide, 0.2% (w/v) BSA (origin USA) and a stabilizer.
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- 200 µg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Suggested for Flow Cytometry
- Recommended Usage
Precautions for Use: Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
AB_2650652 (BioLegend Cat. No. 983202)
- Ig superfamily, type I glycoprotein, 72 kD
Monocytes, macrophages, dendritic cells, activated granulocytes
- Phagocytosis, ADCC
- Ligand Receptor
- IgG receptor
- Cell Type
- Dendritic cells, Granulocytes, Macrophages, Monocytes
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
1. Hulett M, et al. 1994. Adv. Immunol. 57:1.
2. van de Winkel J, et al. 1993. Immunol. Today 14:215.
- Gene ID
- 2209 View all products for this Gene ID
- View information about CD64 on UniProt.org
- Does BioLegend manufacture antibodies at GMP grade?
BioLegend antibodies and reagents that carry the IVD or ASR designation are manufactured in a registered GMP facility, while our other products are manufactured under ISO 13485 certification. Both environments provide high quality products. To learn more about our quality standards visit our Quality Control page at: https://www.biolegend.com/QC.
- Is our human Trustain FcX™ (cat# 422302) compatible with anti human CD16, CD32 and CD64 clones 3G8, FUN-2 and 10.1 respectively?
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
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