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APC anti-human PSMA (FOLH1) Antibody

Pricing & Availability
Clone
LNI-17 (See other available formats)
Regulatory Status
RUO
Other Names
PSM, Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), NAALADase I, FGCP
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
LNI-17_APC_090111
Human prostatic adenocarcinoma cell line LNCaP cells were stained with PSMA (clone LNI-17) APC (filled histogram) or mouse IgG1 APC isotype control (open histogram).
  • LNI-17_APC_090111
    Human prostatic adenocarcinoma cell line LNCaP cells were stained with PSMA (clone LNI-17) APC (filled histogram) or mouse IgG1 APC isotype control (open histogram).
Compare all formats See APC spectral data
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342507 25 tests $178
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342508 100 tests $367
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Description

PSMA (prostate-specific membrane antigen) is a type II transmembrane zinc metallopeptidase, belonging to the M28 peptidase family. It possesses hydrolyzing enzyme activities and is also known as FOLH1 (folate hydrolase 1), GCP2 (glutamate carboxypeptidase II), and NAALADase I (N-acetylated-alpha-linked acidic dipeptidase I). PSMA is expressed by normal and malignant prostate epithelial cells, by urothelial adenocarcinoma, and vasculatures of other malignancies. It is also found in the nervous system.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Product Citations
  1. Samoto M, et al. 2021. Oncol Lett. 22:689. PubMed
  2. Yang Z, et al. 2022. Transl Androl Urol. 11:803. PubMed
RRID
AB_10916527 (BioLegend Cat. No. 342507)
AB_10917056 (BioLegend Cat. No. 342508)

Antigen Details

Structure
Type II transmembrane zinc metallopeptidase, M28 peptidase family
Distribution

Epithelial cells in prostate, intestine and kidney tissue, nervous system

Function
Hydrolyzing enzyme activity
Cell Type
Epithelial cells
Biology Area
Cell Biology
Antigen References

1. Silver DA, et al. 1997. Clin. Cancer Res. 3:81.
2. Troyer JK, et al. 1995. Int. J. Cancer. 62:552.
3. Mannweiler S, et al. 2009. Pathol. Oncol. Res. 15:167.

Gene ID
2346 View all products for this Gene ID
UniProt
View information about PSMA on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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