Purified anti-rat CD26 Antibody

Pricing & Availability
Clone
OX-61 (See other available formats)
Regulatory Status
RUO
Other Names
DPP IV ectoenzyme, gp110
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
OX-61_Pure_022309.jpg
LOU rat splenocytes stained with purified OX-61, followed by anti-mouse IgG FITC
  • OX-61_Pure_022309.jpg
    LOU rat splenocytes stained with purified OX-61, followed by anti-mouse IgG FITC
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203801 100 µg £72
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Description

CD26 is a 110 kD type II membrane protein also known as ADA-binding protein and dipeptidyl peptidase IV (DVPPIV). It is a member of the peptidase and ectoenzyme family. CD26 is expressed on the membrane thymocytes, T lymphocytes (unpregulated upon activation), B cells, NK cells, macrophages, epithelial cells, and endothelial cells. Rat CD26 (unlike in humans) does not bind ADA, but may interact with extracellular matrix proteins such as fibronectin or collagen. CD26 plays an integral role as a costimulatory molecule in T cell activation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
110 kD membrane glycoprotein of rat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F, IP, WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications(for the relevant formats) include: immunoprecipitation, Western blotting, and immunohistochemical staining of acetone-fixed frozen sections.

Application References

(PubMed link indicates BioLegend citation)
  1. Cohen D, et al. 2004. Proc Natl Acad Sci USA 101:13792
RRID
AB_1186182 (BioLegend Cat. No. 203801)

Antigen Details

Biology Area
Immunology, Costimulatory Molecules
Molecular Family
CD Molecules
Gene ID
25253 View all products for this Gene ID
UniProt
View information about CD26 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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