Purified anti-human CD339 (Jagged 1) Antibody

Pricing & Availability
W16199B (See other available formats)
Regulatory Status
Other Names
Rat IgG2a, κ
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Human U251 glioblastoma cells were stained with purified CD339 (Jagged 1) (clone W16199B) (filled histogram) or purified rat IgG2a, κ isotype control (open histogram), followed by anti-rat IgG PE.
  • W16199B_PURE_CD339_Antibody_022620.png
    Human U251 glioblastoma cells were stained with purified CD339 (Jagged 1) (clone W16199B) (filled histogram) or purified rat IgG2a, κ isotype control (open histogram), followed by anti-rat IgG PE.
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399102 100 µg £113
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CD339, also known as Jagged 1, is a 135 kDa type 1 transmembrane protein with one DSL (Delta, Serrate, LagZ) domain, fifteen EGF-like domains, and one cysteine-rich region. Jagged 1 is expressed by many cell types including macrophages, subsets of dendritic cells, astrocytes, stromal, and epithelial cells. Jagged 1 regulates cell fate decisions in various tissues, and has an important role in neurogenesis and development of the cardiovascular system. Some studies suggest Jagged 1 is also involved in Th2 polarization and Treg induction.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Human Jagged-transfected RBL1 cells
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
The antibody was purified by affinity chromatography.
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

AB_2832781 (BioLegend Cat. No. 399102)

Antigen Details

A 135 kD type 1 transmembrane protein with 1 DSL domain, 15 EGF-like domain and 1 cysteine-rich region.

Macrophages, subset of dendritic cells, astrocytes, stromal and epithelial cells.

Regulate cell fate decisions in tissues, neurogenesis, Th2 polarization, and Treg induction
Cell Type
Astrocytes, Dendritic cells, Epithelial cells, Macrophages, Monocytes
Biology Area
Cardiovascular Biology, Immunology, Neuroscience
Molecular Family
CD Molecules
Antigen References
  1. Oda T, et al. 1997. Nat. Genet. 16:235.
  2. Li L, et al. 1997. Nat. Genet. 16:243.
  3. Guarnaccia C, et al. 2004. FEBS Letters. 574:156.
  4. High FA, et al. 2008. Proc. Natl. Acad. Sci. 105:1955.
  5. Kopan R and Ilagan MX. 2009. Cell. 137:216.
  6. Reedijk M, et al. 2005. Cancer Res. 65:8530.
  7. Grochowski CM, et al. 2016. Gene. 576:381.
  8. Hofmann JJ, et al. 2012. Development. 139:4449.
Gene ID
182 View all products for this Gene ID
View information about CD339 on UniProt.org

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Go To Top Version: 1    Revision Date: 02/26/2020

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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