- N331/19 (See other available formats)
- Regulatory Status
- Other Names
- DRD3, D3DR, ETM1, FET1, D(3) dopamine receptor, essential tremor 1
Covance Catalog# MMS-5264
- Mouse IgG2a
- Ave. Rating
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- Product Citations
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This is the D3 subtype of the five (D1-D5) dopamine receptors. D3 subtype receptor activity is mediated by inhibitory G proteins. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions.Product Details
- Antibody Type
- Host Species
- This monoclonal antibody was raised against a fusion protein corresponding to amino acids 223-322 (third intracellular loop) of human Dopamine D3 receptor.
- Phosphate-buffered solution.
- The antibody was purified by affinity chromatography.
- 1 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
ICC - Quality tested
IHC-P, WB - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunocytochemistry. For immunocytochemistry, a concentration of 10.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody is effective in immunocytochemistry (ICC), formalin-fixed paraffin-embedded immunohistochemical staining (IHC-P), and Western blotting (WB).
(PubMed link indicates BioLegend citation)
- Cote SR and Kuzhikandathil EV, et al. 2015. Neurosci. Lett. 585:33. (WB, IHC)
- Ikeda E, et al. 2013. Mol. Pharmacol. 83:959. (WB)
- Product Citations
AB_2564912 (BioLegend Cat. No. 827501)
- Cell Type
- Dopaminergic Neurons
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers, Signal Transduction, Synaptic Biology
- Molecular Family
- Postsynaptic proteins, GPCR
- Gene ID
- 1814 View all products for this Gene ID
- View information about Dopamine D3 receptor on UniProt.org
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