- 3F4-G5-H5 (See other available formats)
- Other Names
- Creatine Kinase, Mitochondrial 2
- Mouse IgG2b, κ
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- Product Citations
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CKMT2 is an isoform of the mitochondrial specific creatine kinase subunit that is mainly expressed in skeletal and heart muscle cells. CKMT2 exists in two different oligomeric forms: dimers and octamers. Recent studies have shown that the homooctameric form of CKMT2 is the predominant form in vivo and is critical to its function.Product Details
- Human, Mouse, Rat
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
WB - Quality tested
IHC-P - Validated
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 10 µg per ml. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 0.5 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- CKMT2 is a 419 amino acid protein with predicted and observed molecular mass of ~47 kD.
Tissue Distribution: Mainly expressed in heart and skeletal muscle. Also expressed in brain.
Cellular Distribution: Mitochondrion and cytosol
- CKMT2 plays a central role in energy transduction in tissues with large, fluctuating energy demands such as the brain.
- CKMT2 exists as octamer composed of four homodimers.
- Biology Area
- Mitochondrial Function, Neurodegeneration, Neuroscience
- Molecular Family
- Mitochondrial Markers
- Antigen References
- Zervou S, et al. 2017. PLoS One. 12(8):e0182994
- Forsey KE, et al. 2013. Mol Reprod Dev. 80(3):185
- Miceli MV, et al. 2005. Exp Cell Res. 302 (2):270
- Gene ID
- 1160 View all products for this Gene ID 76722 View all products for this Gene ID 688698 View all products for this Gene ID
- View information about CKMT2 on UniProt.org
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