- S18016C (See other available formats)
- Regulatory Status
- Other Names
- IL-3Rα, IL-3 Receptor alpha
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Hu CD123 transfectants
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
- Excitation Laser
Blue Laser (488 nm)
AB_2922622 (BioLegend Cat. No. 396609)
AB_2922622 (BioLegend Cat. No. 396610)
- Ig superfamily, type I transmembrane glycoprotein, associates with CDw131, 70 kD
Myeloid precursors, basophils, mast cells, macrophages, dendritic cells, megakaryocytes, subset of lymphocytes
- Hematopoietic cell proliferation, differentiation
- Cell Type
- Basophils, Dendritic cells, Hematopoietic stem and progenitors, Lymphocytes, Macrophages, Mast cells, Megakaryocytes
- Biology Area
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
- Miyajima A, et al. 1993. Blood 82:1960.
- Gene ID
- 3563 View all products for this Gene ID
- View information about CD123 on UniProt.org
- How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?
PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.
|PE anti-human CD123||S18016C||FC|
|Purified anti-human CD123||S18016C||FC|
|PE/Dazzle™ 594 anti-human CD123||S18016C||FC|
|APC anti-human CD123||S18016C||FC|
|PerCP/Cyanine5.5 anti-human CD123||S18016C||FC|
|PE/Cyanine7 anti-human CD123||S18016C||FC|
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