PE anti-rat CD172a (SIRPα) Antibody

Pricing & Availability
OX-41 (See other available formats)
Regulatory Status
Other Names
SIRPa, PTPNS1, BIT, MFR, p84, CD172 antigen-like family member A
Mouse IgG2a, κ
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Product Citations
LOU rat bone marrow cells stained with OX-41 PE (gated on granulocyte population)
  • OX-41_PE_011409.jpg
    LOU rat bone marrow cells stained with OX-41 PE (gated on granulocyte population)
See PE spectral data
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204706 100 µg £106
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Rat CD172a, also known as a signal-regulatory protein α (SIRPα), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs). The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Rat peritoneal macrophages
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: Western blotting3, immunoprecipitation1, and immunohistochemical staining1, 2.

Application References

(PubMed link indicates BioLegend citation)
  1. Robinson AP, et al. 1986. Immunology 57:239. (IP, IHC)
  2. Thai QA, et al. 1999. Stroke 30:140. (IHC)
  3. Adams S, et al. 1998. J. Immunol. 161:1853. (WB)
Product Citations
  1. Liu C, et al. 2022. J Inflamm Res. 15:2803. PubMed
  2. Morandi B, et al. 2013. J Immunol. 191:4858. PubMed
AB_2188080 (BioLegend Cat. No. 204706)

Antigen Details


Monocytes/macrophages, granulocytes, dendritic cells and neurons

Cell Type
Dendritic cells, Granulocytes, Macrophages, Monocytes, Neurons
Biology Area
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Robinson AP, et al. 1986. Immunology 57:239.
2. Thai QA, et al. 1999. Stroke 30:140.
3. Adams S, et al. 1998. J. Immunol. 161:1853.

Gene ID
19261 View all products for this Gene ID
View information about CD172alpha on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 2    Revision Date: 10/25/2016

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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  • Purified anti-rat CD172a (SIRPα)

  • PE anti-rat CD172a (SIRPα)


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