- 39D5 (See other available formats)
- V NK57
- Other Names
- Mouse IgG1, κ
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- Product Citations
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CD56 is a single transmemberane glycoprotein also known as NCAM (neural cell adhesion molecule). It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.Product Details
- Antibody Type
- Host Species
- KG1a cells
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Clone 39D5 recognizes the epitope of CD56 that is selectively expressed on a subset of mesenchymal stem cells (MSC) population which are CD271bright cells. It does not efficiently recognize natural killer cells.
- Product Citations
AB_2561552 (BioLegend Cat. No. 355503)
AB_2561553 (BioLegend Cat. No. 355504)
- Mesenchymal stem cells
- Cell Type
- Mesenchymal Stem Cells
- Biology Area
- Cell Biology, Immunology, Neuroscience, Stem Cells, Synaptic Biology, Costimulatory Molecules
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
1. Battula VL, et al. 2009. Haematologica 94:173.
- Gene ID
- 4684 View all products for this Gene ID
- View information about CD56 on UniProt.org
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
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