APC anti-mouse Notch 4 Antibody

Pricing & Availability
HMN4-14 (See other available formats)
Regulatory Status
Other Names
Proto-oncogene of int-3
Armenian Hamster IgG
Ave. Rating
Submit a Review
Product Citations
FN4/CHO (mouse Notch-4) transfected cell line stained with HMN4-14 APC
  • HMN4-14_APC_092308.jpg
    FN4/CHO (mouse Notch-4) transfected cell line stained with HMN4-14 APC
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
128413 25 µg £92.00
Check Availability

Need larger quantities of this item?
Request Bulk Quote

The Notch receptors and their ligands are highly conserved from invertebrates to mammals.The Delta-like 1 (Dll1) is one of the four or five Notch ligands identified.The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portion of Notch into the nucleus.This translocation triggers a series of signaling process.Delta-like 1 is reported to be essential for the maintenance of marginal zone B cells in normal mice and engagement of Notch 1 by Dll 1 promotes differentiation of B lymphocytes to antibody-secreting cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Antibody Type
Host Species
Armenian Hamster
Notch4-Fc recombinant protein
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg/test. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Moriyama Y, et al.2008. Intl J. Immunol. 20:763.
  2. Reilla LV, et al. 2011. J. Immunol. 187:4629. PubMed.
Product Citations
  1. Riella L, et al. 2011. J Immunol. 187:4629. PubMed
AB_2151253 (BioLegend Cat. No. 128413)

Antigen Details

Type 1 transmembrane receptor with a large extracellular domain consisting of 29 -36 EGF( epidermal growth factor) and three LNR (Lin12-Notch) repeats.

Notch 4 is preferentially expressed in endothelial cells.

Regulation of cell development, including myogenesis, neurogenesis, and lymphocyte development. Notch 4 seems to play a crucial role in vasculogenesis and angiogenesis.
Jagged 1, Jagged2, Delta-like 1, Delta-like3 and Delta-like 4
Cell Type
Endothelial cells
Biology Area
Antigen References

1.Ehebauer MT,et al. 2006. Biochem J.392:13.
2.Shimizu K,et al. 2000.Mol Cell Biology. 20:18
3. Tanigaki K,et al.2007. Nature immunol. 8:451.

Gene ID
18132 View all products for this Gene ID
View information about Notch 4 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • PE anti-mouse Notch 4

  • APC anti-mouse Notch 4

  • TotalSeq™-A0888 anti-mouse Notch 4

  • TotalSeq™-C0888 anti-mouse Notch 4

  • TotalSeq™-B0888 anti-mouse Notch 4 Antibody

Insert Note Here
Save Close Clear
Lab Timer

Login / Register
Remember me
Forgot your password? Reset password?
Create an Account