APC anti-human CD328 (Siglec-7) Antibody

Pricing & Availability
6-434 (See other available formats)
Regulatory Status
VIII 80652
Other Names
Siglec7 (Sialic-binding Ig like lectin 7), p75, AIRM1
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes were stained with CD56 PE and CD328 (clone 6-434) APC (top) or mouse IgG1, κ APC isotype control (bottom).
  • 6-434_APC_CD328_Antibody_FC_1_122214
    Human peripheral blood lymphocytes were stained with CD56 PE and CD328 (clone 6-434) APC (top) or mouse IgG1, κ APC isotype control (bottom).
  • 6-434_APC_CD328_Antibody_FC_2_122214
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339205 25 tests £102
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339206 100 tests £232
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Siglec-7, also known as p75/AIRM1, is a 75 kD type I transmembrane protein and a member of the family of sialic acid-binding immunoglobulin-like lectins (Siglecs). It is primarily found on NK cells and monocytes. The cytoplasmic domain of Siglec-7 contains immunoreceptor tyrosine-based inhibitory motif (ITIM). CD328 mediates sialic acid-dependent cell-cell binding and functions as an inhibitory receptor of NK cells. CD328 preferentially binds to sialylated glycans with α2,8 disialyl and α2,6 sialyl residues.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Product Citations
  1. Maas RJ, et al. 2020. Oncoimmunology. 9:1843247. PubMed
  2. Shemesh A, et al. 2022. J Exp Med. 219:. PubMed
AB_2565238 (BioLegend Cat. No. 339205)
AB_2565239 (BioLegend Cat. No. 339206)

Antigen Details

Type I transmembrane protein, Siglec family member, 75 kD

NK cells, monocytes

Inhibitory receptor of NK cells
Sialylated glycans (with α2,8 disialyl and α2,6 sialyl residues)
Cell Type
Monocytes, NK cells
Biology Area
Molecular Family
CD Molecules, Siglec Molecules
Antigen References
  1. Avril T, et al. 2006. Infection and Immunity 74:4133
  2. Avril T, et al. 2004. J. Immunol. 173:6841
  3. Yamaji T, et al. 2005. Glycobiology 15:667
Gene ID
27036 View all products for this Gene ID
View information about CD328 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 01/02/2015

For Research Use Only. Not for diagnostic or therapeutic use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.


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