- 14C2A07 (See other available formats)
- Regulatory Status
- Other Names
- CLEC15A, MAFA-L, MAFA-2F1, MAFA-LIKE, 2F1
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
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Killer cell lectin-like receptor subfamily G member (KLRG1) is a 30 kD, type II membrane glycoprotein with one C-type lectin domain and one immunoreceptor tyrosine-based inhibitory motif (ITIM). KLRG1 is expressed by subsets of natural killer cells (NKs) and effector and memory T cells. It inhibits cell activation and proliferation and is also a marker of T cell senescence. The binding of KLRG1 to E-, N-, or R- cadherins blocks phosphorylation of AKT and increases the expression of cell cycle inhibitors.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Human KLRG1-transfected cells.
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
AB_2572134 (BioLegend Cat. No. 368607)
AB_2572135 (BioLegend Cat. No. 368608)
- Type II membrane glycoprotein, one C-type lectin domain, one ITIM, 30 kD.
Subsets of natural killer cells, effector and memory T cells.
- Inhibits cell activation and proliferation
- E-, N-, R- cadherins.
- Cell Type
- NK cells, T cells
- Biology Area
- Antigen References
1. Shi L, et al. 2014. J. Immunol. 192:649.
- Gene ID
- 10219 View all products for this Gene ID
- View information about KLRG1 on UniProt.org
Related Pages & Pathways
Other FormatsView All KLRG1 (MAFA) Reagents Request Custom Conjugation
|Purified anti-human KLRG1 (MAFA)||14C2A07||FC|
|Brilliant Violet 421™ anti-human KLRG1 (MAFA)||14C2A07||FC|
|APC anti-human KLRG1 (MAFA)||14C2A07||FC|
|PerCP/Cyanine5.5 anti-human KLRG1 (MAFA)||14C2A07||FC|
|PE anti-human KLRG1 (MAFA)||14C2A07||FC|
|PE/Dazzle™ 594 anti-human KLRG1 (MAFA)||14C2A07||FC|
|PE/Cyanine7 anti-human KLRG1 (MAFA)||14C2A07||FC|
|Alexa Fluor® 488 anti-human KLRG1 (MAFA) Antibody||14C2A07||FC|
|Alexa Fluor® 647 anti-human KLRG1 (MAFA)||14C2A07||FC|
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Purified anti-human KLRG1 (MAFA)
Brilliant Violet 421™ anti-human KLRG1 (MAFA)
APC anti-human KLRG1 (MAFA)
PerCP/Cyanine5.5 anti-human KLRG1 (MAFA)
PE anti-human KLRG1 (MAFA)
PE/Dazzle™ 594 anti-human KLRG1 (MAFA)
PE/Cyanine7 anti-human KLRG1 (MAFA)
Alexa Fluor® 488 anti-human KLRG1 (MAFA) Antibody
Alexa Fluor® 647 anti-human KLRG1 (MAFA)