Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
Ave. Rating
Submit a Review
Product Citations
publications
93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
Compare all formats
Cat # Size Price Quantity Check Availability Save
101301 50 µg 29€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101302 500 µg 92€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  2. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  3. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  4. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  5. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  6. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  7. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  8. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  9. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  10. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  11. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  12. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  13. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  14. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  15. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  16. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  17. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  18. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  19. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  20. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  21. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  22. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  23. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  24. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  25. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  26. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  27. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  28. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  29. Barkaway A, et al. 2021. Immunity. . PubMed
  30. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  31. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  32. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  33. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  34. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  35. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  36. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  37. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  38. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  39. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  40. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  41. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  42. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  43. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  44. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  45. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  46. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  47. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  48. Mevel R, et al. 2020. eLife. 9:00. PubMed
  49. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  50. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  51. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  52. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  53. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  54. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  55. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  56. Goel S, et al. 2017. Nature. 548:471. PubMed
  57. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  58. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  59. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  60. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  61. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  62. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  63. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  64. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  65. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  66. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  67. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  68. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  69. Feng J, et al. 2021. iScience. 24:103004. PubMed
  70. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  71. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  72. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  73. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  74. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  75. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  76. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  77. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  78. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  79. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  80. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  81. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  82. Diao L, et al. 2022. iScience. 25:105511. PubMed
  83. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  84. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  85. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  86. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  87. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  88. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  89. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  90. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  91. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  92. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  93. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  94. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  95. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  96. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  97. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  98. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  99. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  100. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  101. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  102. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  103. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  104. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  105. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  106. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  107. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  108. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  109. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  110. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  111. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  112. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  113. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  114. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  115. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  116. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  117. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  118. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  119. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  120. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  121. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  122. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  123. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  124. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  125. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  126. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  127. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  128. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  129. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  130. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  131. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  132. Tal MC, et al. 2020. MBio. 11:00. PubMed
  133. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  134. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  135. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  136. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  137. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  138. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  139. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  140. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  141. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  142. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  143. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  144. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  145. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  146. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  147. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  148. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  149. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  150. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  151. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  152. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  153. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  154. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  155. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  156. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  157. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  158. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  159. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  160. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  161. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  162. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  163. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  164. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  165. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  166. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  167. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  168. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  169. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  170. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  171. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  172. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  173. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  174. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  175. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  176. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  177. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  178. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  179. Wong HS, et al. 2021. Cell. . PubMed
  180. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  181. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  182. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  183. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  184. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  185. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  186. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  187. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  188. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  189. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  190. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  191. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  192. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  193. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  194. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  195. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  196. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  197. Baasch S, et al. 2021. Cell. . PubMed
  198. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  199. Zheng J, et al. 2020. bioRxiv. . PubMed
  200. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  201. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  202. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  203. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  204. Roy K, et al. 2019. Immunity. 50:616. PubMed
  205. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  206. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  207. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  208. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  209. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  210. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  211. Welte T, et al. 2021. iScience. 24:103349. PubMed
  212. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  213. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  214. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  215. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  216. Xu S, et al. 2021. Immunity. . PubMed
  217. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  218. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  219. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  220. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  221. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  222. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  223. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  224. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  225. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  226. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  227. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  228. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  229. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  230. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  231. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  232. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  233. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  234. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  235. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  236. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  237. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  238. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  239. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  240. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  241. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  242. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  243. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  244. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  245. Zheng J, et al. 2020. Nature. . PubMed
  246. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  247. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  248. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  249. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  250. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  251. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  252. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  253. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  254. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  255. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  256. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  257. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  258. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  259. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  260. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  261. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  262. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  263. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  264. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  265. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  266. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  267. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  268. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  269. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  270. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  271. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  272. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  273. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  274. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  275. Lenert R 2005. J Immunol. 174:2429. PubMed
  276. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  277. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  278. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  279. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  280. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  281. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  282. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  283. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  284. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  285. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  286. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  287. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  288. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  289. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  290. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  291. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  292. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  293. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  294. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  295. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  296. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  297. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  298. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  299. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  300. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  301. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  302. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  303. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  304. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  305. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  306. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  307. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  308. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  309. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  310. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  311. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  312. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  313. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  314. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  315. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  316. William M, et al. 2018. J Immunol. 200:4102. PubMed
  317. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  318. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  319. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  320. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  321. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  322. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  323. Lee SA, et al. 2021. Cells. 10:. PubMed
  324. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  325. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  326. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  327. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  328. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  329. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  330. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  331. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  332. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  333. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  334. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  335. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  336. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  337. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  338. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  339. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  340. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  341. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  342. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  343. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  344. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  345. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  346. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  347. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  348. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  349. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  350. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  351. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  352. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  353. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  354. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  355. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  356. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  357. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  358. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  359. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  360. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  361. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  362. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  363. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  364. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  365. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  366. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  367. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  368. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  369. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  370. Sibler E, et al. 2021. Cells. 10:. PubMed
  371. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  372. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  373. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  374. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  375. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  376. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  377. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  378. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  379. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  380. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  381. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  382. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  383. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  384. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
  385. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
  386. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  387. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  388. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312801 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
UniProt
View information about CD16/32 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 01-23-2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere

Login / Register
Remember me
Forgot your password? Reset password?
Create an Account