PE anti-human Delta Opioid Receptor Antibody

Pricing & Availability
DOR7D2A4 (See other available formats)
Regulatory Status
Other Names
Mouse IgG2b, κ
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Human Opiod Receptor-transfected cells stained with DOR7D2A4 PE
  • DOR7D2A4_PE_021009.jpg
    Human Opiod Receptor-transfected cells stained with DOR7D2A4 PE
See PE spectral data
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327206 100 tests 254€
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Opioid receptors are the members of seven transmembrane G-protein coupled receptors. At least 3 types of opioid receptors, µ, κ, and δ, have been identified. Human δ-opioid receptor, know as OPRD, DOR, or hDOR, is primarily expressed in brain, especially in the areas of cortex, including olfactory bulb, hippocampus, and amygdale, as well as in basal ganglia and hypothalamus. Human OPRD gene has been mapped at chromosome 1p34.3-p36.1. The endogenous ligands for the OPRD are enkephalins. The third extracellular loop of the OPRD is critical for ligand binding. The ligands binding and signal transduction functions of δ-receptor can be synergized by forming heterodimers with κ-receptor. Activation of opioid receptor inhibits cAMP production, increases phosphodiesterase activity, and results in analgesia and convulsions. Recent studies have indicated that OPRD is involved in the mechanism of heroin dependence.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
HEK-293/human Delta Opioid Receptor
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
AB_2298899 (BioLegend Cat. No. 327206)

Antigen Details

Seven transmembrane G-protein coupled receptor

Brain cortical area, including olfactory bulb, hippocampus, and amygdale, nucleus accumbens

Inhibit cAMP production, increase phosphodiesterase activity, control anxiety, depression, and pain
Biology Area
Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers
Molecular Family
Antigen References

1. Simonin F, et al. 1994. Mol. Pharmacol. 46:1015.
2. Befort K, et al. 1994. Genomics 20:143.
3. Bzdega T, et al. 1993. Proc. Nat. Acad. Sci. 90:9305.
4. Jordan BA. And LA Devi. 1999. Nature 399:697.
5. Xue K, et al. 2002. Am. J. Med. Genet. 11:45.

Gene ID
4985 View all products for this Gene ID
View information about Delta Opioid Receptor on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

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  • PE anti-human Delta Opioid Receptor


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