- SA231A2 (See other available formats)
- Regulatory Status
- Other Names
- CLEC15A, MAFA-L, MAFA-2F1, MAFA-LIKE, 2F1
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a 30 kD, type II membrane glycoprotein with one C-type lectin domain and one immunoreceptor tyrosine-based inhibititory motif (ITIM). KLRG1 is expressed by subsets of NK, effector and memory T cells. KLRG1 inhibits cell activation and proliferation, and is a marker of T cell senescence. Binding of KLRG1 to E-, N-, or R- cadherins blocks phosphorylation of Akt and increases the expression of cell cycle inhibitors.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Human KLRG1-transfected cells
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with APC/Fire™ 810 under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2˚C and 8˚C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* APC/Fire™ 810 has a maximum excitation of 650 nm and a maximum emission of 810 nm.
Excessive exposure to light, and commonly used fixation, permeabilization buffers can affect APC/Fire™ 810 fluorescence signal intensity and spread. Please keep conjugates protected from light exposure. For more information and representative data, visit our Fire Dyes page.
- Excitation Laser
Red Laser (633 nm)
AB_2894495 (BioLegend Cat. No. 367731)
AB_2894495 (BioLegend Cat. No. 367732)
- Type II membrane glycoprotein, one C-type lectin domain, one ITIM, 30 kD.
Subsets of NK, effector and memory T cells.
- Inhibits cell activation and proliferation, marker of T cell senescence.
- E-, N-, and R- cadherins
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Antigen References
1. Shi L, et al. 2014. J. Immunol. 192:649.
- Gene ID
- 10219 View all products for this Gene ID
- View information about KLRG1 on UniProt.org
Related Pages & Pathways
Other FormatsView All KLRG1 Reagents Request Custom Conjugation
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-human KLRG1 (MAFA)
Alexa Fluor® 647 anti-human KLRG1 (MAFA)
Brilliant Violet 421™ anti-human KLRG1 (MAFA)
PerCP/Cyanine5.5 anti-human KLRG1 (MAFA)
PE/Dazzle™ 594 anti-human KLRG1 (MAFA)
APC anti-human KLRG1 (MAFA)
PE anti-human KLRG1 (MAFA)
FITC anti-human KLRG1 (MAFA)
APC/Fire™ 750 anti-human KLRG1 (MAFA)
PE/Cyanine7 anti-human KLRG1 (MAFA)
TotalSeq™-A0153 anti-human KLRG1 (MAFA)
APC/Cyanine7 anti-human KLRG1 (MAFA)
KIRAVIA Blue 520™ anti-human KLRG1 (MAFA) Antibody
TotalSeq™-B0153 anti-human KLRG1 (MAFA) Antibody
Alexa Fluor® 700 anti-human KLRG1 (MAFA)
APC/Fire™ 810 anti-human KLRG1 (MAFA) Antibody
TotalSeq™-D0153 anti-human KLRG1 (MAFA)
PE/Fire™ 810 anti-human KLRG1 (MAFA) Antibody
TotalSeq™-C0153 anti-human KLRG1 (MAFA)
Spark NIR™ 685 anti-human KLRG1 (MAFA)
PE/Fire™ 640 anti-human KLRG1 (MAFA)
Brilliant Violet 711™ anti-human KLRG1 (MAFA)