PerCP/Cyanine5.5 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_PerCPCyanine55_CD11b_Antibody_111918
C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
  • M1slash70_PerCPCyanine55_CD11b_Antibody_111918
    C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
Compare all formats See PerCP/Cyanine5.5 spectral data
Cat # Size Price Quantity Check Availability Save
101227 25 µg 72€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101228 100 µg 234€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11b antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Additional Product Notes
BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
Application References
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Lee T, et al. 2014. Mol Biol Cell. 25:583. PubMed
  2. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  3. Orberg E, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.53. PubMed
  4. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  5. Milasan A, et al. 2017. J Am Heart Assoc. 10.1161/JAHA.117.006892. PubMed
  6. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  7. Lang J, et al. 2020. Nat Commun. 11:1338. PubMed
  8. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  9. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  10. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  11. Grandjean CL, et al. 2021. Sci Adv. 7:. PubMed
  12. Leslie J, et al. 2021. Sci Rep. 11:1415. PubMed
  13. Zheng J, et al. 2022. Front Pharmacol. 13:866228. PubMed
  14. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  15. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  16. Wilden A, et al. 2022. Front Immunol. 13:991295. PubMed
  17. McNamara HA, et al. 2020. Cell Host Microbe. 572:28. PubMed
  18. Bouchareychas L, et al. 2021. iScience. 24(8):102847. PubMed
  19. Gern BH, et al. 2021. Cell Host Microbe. 29(4):594-606.e6. PubMed
  20. Kaczanowska S, et al. 2021. Cell. 184(8):2033-2052.e21. PubMed
  21. John S, et al. 2020. Sci Rep. 10:11377. PubMed
  22. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  23. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  24. Huang X, et al. 2021. Stem Cells Int. 2021:8138374. PubMed
  25. Hong M, et al. 2021. Int J Mol Sci. 22:. PubMed
  26. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  27. Zhao X, et al. 2022. Front Mol Biosci. 9:786864. PubMed
  28. Meng W, et al. 2021. JCI Insight. 6:. PubMed
  29. Ortiz G, et al. 2020. Front Immunol. 11:1713. PubMed
  30. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  31. Leach SM, et al. 2020. Cell Rep. 33:108337. PubMed
  32. Dong L, et al. 2021. Cancer Cell. . PubMed
  33. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  34. Fu B et al. 2017. Immunity. 47(6):1100-1113 . PubMed
  35. Chen L, et al. 2019. Cell Mol Gastroenterol Hepatol. 7:623. PubMed
  36. Kenichi Shimada et al. 2018. Immunity. 49(5):873-885 . PubMed
  37. Kobayashi T, et al. 2019. Cell. 176:982. PubMed
  38. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  39. Súarez-López L, et al. 2021. iScience. 24:103406. PubMed
  40. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  41. Hirano KI, et al. 2021. eLife. 0.416666666666667. PubMed
  42. Yuan Q, et al. 2021. Cell Reports. 34(5):108724. PubMed
  43. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  44. Amano C, et al. 2015. PLoS One. 10: 0137207. PubMed
  45. Sun P, et al. 2015. J Hepatol. . PubMed
  46. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  47. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  48. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  49. Tan X, et al. 2021. Front Oncol. 11:768222. PubMed
  50. Biswas S, et al. 2021. Nature. 591:464. PubMed
  51. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  52. Neubert K, et al. 2014. J Immunol. 192:5830. PubMed
  53. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  54. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  55. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  56. Nguyen SL, et al. 2021. Sci Rep. 11:4217. PubMed
  57. Cai B, et al. 2021. Mol Cancer. 20:165. PubMed
  58. Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
  59. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  60. Galle E, et al. 2022. Genome Biol. 23:207. PubMed
  61. Jiao H, et al. 2021. Cell. 184(11):2896-2910.e13. PubMed
  62. Lu S, et al. 2020. JCI Insight. 5:00. PubMed
  63. Koh EH, et al. 2018. Diabetes. 67(12). PubMed
  64. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  65. Anastasiou M, et al. 2021. JCI Insight. 6:. PubMed
  66. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  67. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  68. Plein A, et al. 2018. Nature. 562:223. PubMed
  69. Jeong SJ, et al. 2021. Autophagy. 17:3740. PubMed
  70. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  71. Bunn P, et al. 2014. J Immunol. 192:3709. PubMed
  72. Nishi C, et al. 2014. Mol Cell Biol. 34:1512. PubMed
  73. Fulham MA, et al. 2019. Am J Physiol Cell Physiol. 317:C687. PubMed
  74. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  75. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  76. Xu G, et al. 2022. Cell Death Dis. 13:888. PubMed
  77. Raineri D, et al. 2021. Biomedicines. 10:. PubMed
  78. Park D, et al. 2020. Cancer Res. 80:4172. PubMed
  79. Bretscher P, et al. 2015. EMBO Mol Med. 7:593. PubMed
  80. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  81. Qi T, et al. 2020. Cell Rep. 33:108452. PubMed
  82. Bogie JF, et al. 2020. Ther Adv Chronic Dis. 11:2040622320947378. PubMed
  83. Nayak RR, et al. 2021. Cell Host Microbe. 29(3):362-377.e11. PubMed
  84. Zhang F, et al. 2020. EMBO Mol Med. e12034:12. PubMed
  85. Yue X, et al. 2019. Nat Commun. 10:2011. PubMed
  86. Pereira JA, et al. 2020. Hum Mol Genet. 29:1253. PubMed
  87. Lu CY, et al. 2020. J Neurosci. 40:9602. PubMed
  88. Okamura T, et al. 2021. Front Immunol. 12:669629. PubMed
  89. Qian SJ, et al. 2021. Front Immunol. 12:711337. PubMed
  90. Wang J, et al. 2021. Nat Commun. 12:6198. PubMed
  91. Fennell LM, et al. 2020. EMBO J. 39:e103303. PubMed
  92. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  93. Li W, et al. 2021. Front Pharmacol. 12:697483. PubMed
  94. Yu Y, et al. 2022. Nat Commun. 13:6857. PubMed
  95. Xu Z, et al. 2020. Cancer Immunol Res. 1354:8. PubMed
  96. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  97. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  98. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  99. Lu S, et al. 2020. Arterioscler Thromb Vasc Biol. 40:394. PubMed
  100. Sun L, et al. 2015. J Immunol. 194:4891. PubMed
  101. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  102. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  103. Wei W, et al. 2022. mSystems. 7:e0046922. PubMed
  104. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  105. Xu M, et al. 2022. Genes Dis. 9:429. PubMed
  106. Sharma A, et al. 2020. Cell. 183(2):377-394.e21. PubMed
  107. Liu Z, et al. 2021. Immunity. 54(2):247-258.e7. PubMed
  108. Chung L et al. 2018. Cell host & microbe. 23(2):203-214 . PubMed
  109. Sasaki T, et al. 2020. Cell Reports. 28(1):202-217.e7.. PubMed
  110. Deczkowska A, et al. 2017. Nat Commun. 8:717. PubMed
  111. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  112. Carbone C, et al. 2021. J Immunother Cancer. 9:. PubMed
  113. Dagher T, et al. 2021. J Exp Med. 218:. PubMed
  114. Anger-Góra N, et al. 2021. Oncol Lett. 22:582. PubMed
  115. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  116. Stowe CL, et al. 2019. eLife. 0.333333333333333. PubMed
  117. Chatterjee D, et al. 2021. Cell Reports. 35(2):108996. PubMed
  118. Grauel AL, et al. 2020. Nat Commun. 4.84375. PubMed
  119. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  120. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  121. Lin W, et al. 2019. EBioMedicine. 49:133. PubMed
  122. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  123. Brown SM et al. 2017. Endocrinology. 158(10):3592-3604 . PubMed
  124. López MJ, et al. 2018. Invest Ophthalmol Vis Sci. 59:5671. PubMed
  125. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  126. Wu S, et al. 2022. BMC Immunol. 23:17. PubMed
  127. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  128. Zhao D, et al. 2020. Cancer Discov. 10:1374. PubMed
  129. Cruz-Herranz A, et al. 2021. JCI Insight. 6: . PubMed
  130. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  131. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  132. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  133. Bhattacharya A, et al. 2018. Neuropsychopharmacology. 43:2586. PubMed
  134. Carestia A, et al. 2019. Cell Rep. 28:896. PubMed
  135. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  136. Chruewkamlow N, et al. 2021. Stem Cell Res Ther. 12:520. PubMed
  137. Vachon L, et al. 2022. Theranostics. 12:1440. PubMed
  138. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  139. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  140. Ni C, et al. 2021. Infect Immun. 89:. PubMed
  141. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  142. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  143. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  144. Sharif O, et al. 2013. J Immunol. 190:5640. PubMed
  145. Dulken BW, et al. 2019. Nature. 571:205. PubMed
  146. Muri J, et al. 2020. eLife. 9:e53627.. PubMed
  147. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  148. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  149. Hightower RM, et al. 2019. Mol Ther. 28:189. PubMed
  150. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  151. Bitschar K, et al. 2019. Nat Commun. 10:2730. PubMed
  152. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  153. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  154. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  155. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  156. Raoof R, et al. 2021. J Neurosci. 41:8249. PubMed
  157. Guo D, et al. 2022. Bone Res. 10:45. PubMed
  158. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  159. Bennett FC, et al. 2018. Neuron. 98:1170. PubMed
  160. Yang X, et al. 2018. Sci Rep. 8:188. PubMed
  161. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  162. Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
  163. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  164. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  165. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  166. Unsinger J, et al. 2021. J Leukoc Biol. 109:697. PubMed
  167. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  168. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  169. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  170. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  171. Liao Y, et al. 2020. Theranostics. 7.113888889. PubMed
  172. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  173. Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
  174. Muchenditsi A, et al. 2017. Am J Physiol Gastrointest Liver Physiol. 313:G39. PubMed
  175. Tothova Z et al. 2017. Cell stem cell. 21(4):547-555 . PubMed
  176. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  177. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  178. Xu JL, et al. 2022. Front Pharmacol. 13:911663. PubMed
  179. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  180. Hakim R, et al. 2021. J Neurosci. 41:8441. PubMed
  181. Gu H, et al. 2021. Elife. 10:. PubMed
  182. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  183. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  184. Chen J, et al. 2017. Sci Rep. 10.1038/s41598-017-00654-2. PubMed
  185. Danzer H, et al. 2020. Elife. 9:00. PubMed
  186. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  187. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  188. Starr T, et al. 2018. PLoS One. 13:e0193601. PubMed
  189. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  190. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  191. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  192. Jaitin DA et al. 2016. Cell. 167(7):1883-1896 . PubMed
  193. Zhang J, et al. 2018. Oncoimmunology. 7:e1461301. PubMed
  194. Molgora M, et al. 2020. Cell. 182:886. PubMed
  195. Werner A, et al. 2021. iScience. 24:103076. PubMed
  196. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  197. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  198. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  199. Baptista M, et al. 2016. Nat Commun. 7:12175. PubMed
  200. Guey B, et al. 2014. Proc Natl Acad Sci U S A. 111:17254. PubMed
  201. Ramanan D, et al. 2020. Cell. 181(6):1276-1290. PubMed
  202. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  203. Bohlen CJ et al. 2017. Neuron. 94(4):759-773 . PubMed
  204. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  205. Ishihara J, et al. 2018. Nat Commun. 9:2163. PubMed
  206. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  207. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  208. Sakamoto K, et al. 2022. STAR Protoc. 3:101052. PubMed
  209. Tummala G, et al. 2021. Invest Ophthalmol Vis Sci. 62:41. PubMed
  210. Maller O, et al. 2020. Nat Mater. 20:548. PubMed
  211. Lee J, et al. 2015. Nat Commun. 6: 8499. PubMed
  212. Sen D, et al. 2016. PLoS One. 11:e0165064. PubMed
  213. Liddelow S, et al. 2017. Nature. 541:481-487. PubMed
  214. Xu Z, et al. 2020. Cell Rep. 32:108041. PubMed
  215. Ang QY, et al. 2020. Cell. 181(6):1263-1275.e16. PubMed
  216. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  217. Koyama M et al. 2019. Immunity. 51(5):885-898 . PubMed
  218. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  219. Tripathi A, et al. 2021. Mol Psychiatry. 26:3043. PubMed
  220. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  221. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  222. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  223. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  224. Kapralov AA, et al. 2020. Nat Chem Biol. 278:16. PubMed
  225. Zheng H, et al. 2021. Frontiers in Immunology. 12:645100. PubMed
  226. Han J, et al. 2015. Cancer Res . 75: 5273 - 5282. PubMed
  227. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  228. Strattan E, et al. 2020. Frontiers in Immunology. 2.131944444. PubMed
  229. Ribechini E, et al. 2017. Blood Adv. 0.699305556. PubMed
  230. Tan DQ, et al. 2019. Cell Rep. 26:2316. PubMed
  231. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  232. Aurélien Trompette et al. 2018. Immunity. 48(5):992-1005 . PubMed
  233. Chithanathan K, et al. 2022. Biology (Basel). 11:. PubMed
  234. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  235. Erens C, et al. 2022. Biomedicines. 10:. PubMed
  236. Yang F, et al. 2021. Nat Commun. 12:3424. PubMed
RRID
AB_893233 (BioLegend Cat. No. 101227)
AB_893232 (BioLegend Cat. No. 101228)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC, IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC, CyTOF®, IP, IHC-F, ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC, IHC-F, 3D IHC, SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC, 3D IHC
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC, ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC, CyTOF®, IP, Block, Depletion, IHC-F, ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC, CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F, FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
Go To Top Version: 2    Revision Date: 11/19/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • APC anti-mouse/human CD11b

  • Biotin anti-mouse/human CD11b

  • FITC anti-mouse/human CD11b

  • PE anti-mouse/human CD11b

  • PE/Cyanine5 anti-mouse/human CD11b

  • Purified anti-mouse/human CD11b

  • PE/Cyanine7 anti-mouse/human CD11b

  • Alexa Fluor® 488 anti-mouse/human CD11b

  • Alexa Fluor® 647 anti-mouse/human CD11b

  • Alexa Fluor® 700 anti-mouse/human CD11b

  • Pacific Blue™ anti-mouse/human CD11b

  • APC/Cyanine7 anti-mouse/human CD11b

  • PerCP/Cyanine5.5 anti-mouse/human CD11b

  • PerCP anti-mouse/human CD11b

  • Brilliant Violet 421™ anti-mouse/human CD11b

  • Brilliant Violet 570™ anti-mouse/human CD11b

  • Brilliant Violet 605™ anti-mouse/human CD11b

  • Brilliant Violet 650™ anti-mouse/human CD11b

  • Brilliant Violet 711™ anti-mouse/human CD11b

  • Brilliant Violet 785™ anti-mouse/human CD11b

  • Brilliant Violet 510™ anti-mouse/human CD11b

  • Ultra-LEAF™ Purified anti-mouse/human CD11b

  • Purified anti-mouse/human CD11b (Maxpar® Ready)

  • Alexa Fluor® 594 anti-mouse/human CD11b

  • PE/Dazzle™ 594 anti-mouse/human CD11b

  • APC/Fire™ 750 anti-mouse/human CD11b

  • TotalSeq™-A0014 anti-mouse/human CD11b

  • Brilliant Violet 750™ anti-mouse/human CD11b

  • TotalSeq™-B0014 anti-mouse/human CD11b

  • TotalSeq™-C0014 anti-mouse/human CD11b

  • Spark NIR™ 685 anti-mouse/human CD11b

  • PE/Fire™ 640 anti-mouse/human CD11b

  • Spark YG™ 593 anti-mouse/human CD11b

  • Spark YG™ 570 anti-mouse/human CD11b

  • PE/Fire™ 810 anti-mouse/human CD11b

  • APC/Fire™ 810 anti-mouse/human CD11b Antibody

  • Spark Blue™ 550 anti-mouse/human CD11b

  • Spark UV™ 387 anti-mouse/human CD11b

ProductsHere

Login / Register
Remember me
Forgot your password? Reset password?
Create an Account