PerCP/Cyanine5.5 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_PerCPCyanine55_CD11b_Antibody_111918
C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
  • M1slash70_PerCPCyanine55_CD11b_Antibody_111918
    C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
Compare all formats See PerCP/Cyanine5.5 spectral data
Cat # Size Price Quantity Check Availability Save
101227 25 µg 72€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101228 100 µg 234€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11b antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Additional Product Notes
BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
Application References
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  2. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  3. Grandjean CL, et al. 2021. Sci Adv. 7:. PubMed
  4. Leslie J, et al. 2021. Sci Rep. 11:1415. PubMed
  5. Zheng J, et al. 2022. Front Pharmacol. 13:866228. PubMed
  6. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  7. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  8. Wilden A, et al. 2022. Front Immunol. 13:991295. PubMed
  9. Lee T, et al. 2014. Mol Biol Cell. 25:583. PubMed
  10. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  11. Orberg E, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.53. PubMed
  12. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  13. Milasan A, et al. 2017. J Am Heart Assoc. 10.1161/JAHA.117.006892. PubMed
  14. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  15. Lang J, et al. 2020. Nat Commun. 11:1338. PubMed
  16. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  17. Kim SS, et al. 2022. Cancers (Basel). 14:. PubMed
  18. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  19. Huang X, et al. 2021. Stem Cells Int. 2021:8138374. PubMed
  20. Hong M, et al. 2021. Int J Mol Sci. 22:. PubMed
  21. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  22. Zhao X, et al. 2022. Front Mol Biosci. 9:786864. PubMed
  23. Meng W, et al. 2021. JCI Insight. 6:. PubMed
  24. Ortiz G, et al. 2020. Front Immunol. 11:1713. PubMed
  25. McNamara HA, et al. 2020. Cell Host Microbe. 572:28. PubMed
  26. Bouchareychas L, et al. 2021. iScience. 24(8):102847. PubMed
  27. Gern BH, et al. 2021. Cell Host Microbe. 29(4):594-606.e6. PubMed
  28. Kaczanowska S, et al. 2021. Cell. 184(8):2033-2052.e21. PubMed
  29. John S, et al. 2020. Sci Rep. 10:11377. PubMed
  30. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  31. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  32. Súarez-López L, et al. 2021. iScience. 24:103406. PubMed
  33. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  34. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  35. Leach SM, et al. 2020. Cell Rep. 33:108337. PubMed
  36. Dong L, et al. 2021. Cancer Cell. . PubMed
  37. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  38. Fu B et al. 2017. Immunity. 47(6):1100-1113 . PubMed
  39. Chen L, et al. 2019. Cell Mol Gastroenterol Hepatol. 7:623. PubMed
  40. Kenichi Shimada et al. 2018. Immunity. 49(5):873-885 . PubMed
  41. Kobayashi T, et al. 2019. Cell. 176:982. PubMed
  42. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  43. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  44. Tan X, et al. 2021. Front Oncol. 11:768222. PubMed
  45. Biswas S, et al. 2021. Nature. 591:464. PubMed
  46. Hirano KI, et al. 2021. eLife. 0.416666666666667. PubMed
  47. Yuan Q, et al. 2021. Cell Reports. 34(5):108724. PubMed
  48. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  49. Amano C, et al. 2015. PLoS One. 10: 0137207. PubMed
  50. Sun P, et al. 2015. J Hepatol. . PubMed
  51. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  52. Nguyen SL, et al. 2021. Sci Rep. 11:4217. PubMed
  53. Cai B, et al. 2021. Mol Cancer. 20:165. PubMed
  54. Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
  55. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  56. Galle E, et al. 2022. Genome Biol. 23:207. PubMed
  57. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  58. Neubert K, et al. 2014. J Immunol. 192:5830. PubMed
  59. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  60. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  61. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  62. Anastasiou M, et al. 2021. JCI Insight. 6:. PubMed
  63. Jiao H, et al. 2021. Cell. 184(11):2896-2910.e13. PubMed
  64. Lu S, et al. 2020. JCI Insight. 5:00. PubMed
  65. Koh EH, et al. 2018. Diabetes. 67(12). PubMed
  66. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  67. Jeong SJ, et al. 2021. Autophagy. 17:3740. PubMed
  68. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  69. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  70. Plein A, et al. 2018. Nature. 562:223. PubMed
  71. Xu G, et al. 2022. Cell Death Dis. 13:888. PubMed
  72. Raineri D, et al. 2021. Biomedicines. 10:. PubMed
  73. Park D, et al. 2020. Cancer Res. 80:4172. PubMed
  74. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  75. Bunn P, et al. 2014. J Immunol. 192:3709. PubMed
  76. Nishi C, et al. 2014. Mol Cell Biol. 34:1512. PubMed
  77. Fulham MA, et al. 2019. Am J Physiol Cell Physiol. 317:C687. PubMed
  78. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  79. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  80. Lu CY, et al. 2020. J Neurosci. 40:9602. PubMed
  81. Okamura T, et al. 2021. Front Immunol. 12:669629. PubMed
  82. Qian SJ, et al. 2021. Front Immunol. 12:711337. PubMed
  83. Wang J, et al. 2021. Nat Commun. 12:6198. PubMed
  84. Fennell LM, et al. 2020. EMBO J. 39:e103303. PubMed
  85. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  86. Li W, et al. 2021. Front Pharmacol. 12:697483. PubMed
  87. Yu Y, et al. 2022. Nat Commun. 13:6857. PubMed
  88. Bretscher P, et al. 2015. EMBO Mol Med. 7:593. PubMed
  89. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  90. Qi T, et al. 2020. Cell Rep. 33:108452. PubMed
  91. Bogie JF, et al. 2020. Ther Adv Chronic Dis. 11:2040622320947378. PubMed
  92. Nayak RR, et al. 2021. Cell Host Microbe. 29(3):362-377.e11. PubMed
  93. Zhang F, et al. 2020. EMBO Mol Med. e12034:12. PubMed
  94. Yue X, et al. 2019. Nat Commun. 10:2011. PubMed
  95. Pereira JA, et al. 2020. Hum Mol Genet. 29:1253. PubMed
  96. Wei W, et al. 2022. mSystems. 7:e0046922. PubMed
  97. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  98. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  99. Xu M, et al. 2022. Genes Dis. 9:429. PubMed
  100. Xu Z, et al. 2020. Cancer Immunol Res. 1354:8. PubMed
  101. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  102. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  103. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  104. Lu S, et al. 2020. Arterioscler Thromb Vasc Biol. 40:394. PubMed
  105. Sun L, et al. 2015. J Immunol. 194:4891. PubMed
  106. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  107. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  108. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  109. Carbone C, et al. 2021. J Immunother Cancer. 9:. PubMed
  110. Dagher T, et al. 2021. J Exp Med. 218:. PubMed
  111. Anger-Góra N, et al. 2021. Oncol Lett. 22:582. PubMed
  112. Sharma A, et al. 2020. Cell. 183(2):377-394.e21. PubMed
  113. Liu Z, et al. 2021. Immunity. 54(2):247-258.e7. PubMed
  114. Chung L et al. 2018. Cell host & microbe. 23(2):203-214 . PubMed
  115. Sasaki T, et al. 2020. Cell Reports. 28(1):202-217.e7.. PubMed
  116. Deczkowska A, et al. 2017. Nat Commun. 8:717. PubMed
  117. Wu S, et al. 2022. BMC Immunol. 23:17. PubMed
  118. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  119. Zhao D, et al. 2020. Cancer Discov. 10:1374. PubMed
  120. Cruz-Herranz A, et al. 2021. JCI Insight. 6: . PubMed
  121. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  122. Stowe CL, et al. 2019. eLife. 0.333333333333333. PubMed
  123. Chatterjee D, et al. 2021. Cell Reports. 35(2):108996. PubMed
  124. Grauel AL, et al. 2020. Nat Commun. 4.84375. PubMed
  125. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  126. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  127. Lin W, et al. 2019. EBioMedicine. 49:133. PubMed
  128. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  129. Brown SM et al. 2017. Endocrinology. 158(10):3592-3604 . PubMed
  130. López MJ, et al. 2018. Invest Ophthalmol Vis Sci. 59:5671. PubMed
  131. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  132. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  133. Chruewkamlow N, et al. 2021. Stem Cell Res Ther. 12:520. PubMed
  134. Vachon L, et al. 2022. Theranostics. 12:1440. PubMed
  135. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  136. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  137. Ni C, et al. 2021. Infect Immun. 89:. PubMed
  138. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  139. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  140. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  141. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  142. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  143. Bhattacharya A, et al. 2018. Neuropsychopharmacology. 43:2586. PubMed
  144. Carestia A, et al. 2019. Cell Rep. 28:896. PubMed
  145. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  146. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  147. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  148. Raoof R, et al. 2021. J Neurosci. 41:8249. PubMed
  149. Guo D, et al. 2022. Bone Res. 10:45. PubMed
  150. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  151. Sharif O, et al. 2013. J Immunol. 190:5640. PubMed
  152. Dulken BW, et al. 2019. Nature. 571:205. PubMed
  153. Muri J, et al. 2020. eLife. 9:e53627.. PubMed
  154. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  155. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  156. Hightower RM, et al. 2019. Mol Ther. 28:189. PubMed
  157. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  158. Bitschar K, et al. 2019. Nat Commun. 10:2730. PubMed
  159. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  160. Unsinger J, et al. 2021. J Leukoc Biol. 109:697. PubMed
  161. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  162. Bennett FC, et al. 2018. Neuron. 98:1170. PubMed
  163. Yang X, et al. 2018. Sci Rep. 8:188. PubMed
  164. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  165. Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
  166. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  167. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  168. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  169. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  170. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  171. Xu JL, et al. 2022. Front Pharmacol. 13:911663. PubMed
  172. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  173. Hakim R, et al. 2021. J Neurosci. 41:8441. PubMed
  174. Gu H, et al. 2021. Elife. 10:. PubMed
  175. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  176. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  177. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  178. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  179. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  180. Liao Y, et al. 2020. Theranostics. 7.113888889. PubMed
  181. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  182. Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
  183. Muchenditsi A, et al. 2017. Am J Physiol Gastrointest Liver Physiol. 313:G39. PubMed
  184. Tothova Z et al. 2017. Cell stem cell. 21(4):547-555 . PubMed
  185. Molgora M, et al. 2020. Cell. 182:886. PubMed
  186. Werner A, et al. 2021. iScience. 24:103076. PubMed
  187. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  188. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  189. Chen J, et al. 2017. Sci Rep. 10.1038/s41598-017-00654-2. PubMed
  190. Danzer H, et al. 2020. Elife. 9:00. PubMed
  191. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  192. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  193. Starr T, et al. 2018. PLoS One. 13:e0193601. PubMed
  194. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  195. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  196. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  197. Jaitin DA et al. 2016. Cell. 167(7):1883-1896 . PubMed
  198. Zhang J, et al. 2018. Oncoimmunology. 7:e1461301. PubMed
  199. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  200. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  201. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  202. Sakamoto K, et al. 2022. STAR Protoc. 3:101052. PubMed
  203. Tummala G, et al. 2021. Invest Ophthalmol Vis Sci. 62:41. PubMed
  204. Maller O, et al. 2020. Nat Mater. 20:548. PubMed
  205. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  206. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  207. Baptista M, et al. 2016. Nat Commun. 7:12175. PubMed
  208. Guey B, et al. 2014. Proc Natl Acad Sci U S A. 111:17254. PubMed
  209. Ramanan D, et al. 2020. Cell. 181(6):1276-1290. PubMed
  210. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  211. Bohlen CJ et al. 2017. Neuron. 94(4):759-773 . PubMed
  212. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  213. Ishihara J, et al. 2018. Nat Commun. 9:2163. PubMed
  214. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  215. Tripathi A, et al. 2021. Mol Psychiatry. 26:3043. PubMed
  216. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  217. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  218. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  219. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  220. Lee J, et al. 2015. Nat Commun. 6: 8499. PubMed
  221. Sen D, et al. 2016. PLoS One. 11:e0165064. PubMed
  222. Liddelow S, et al. 2017. Nature. 541:481-487. PubMed
  223. Xu Z, et al. 2020. Cell Rep. 32:108041. PubMed
  224. Ang QY, et al. 2020. Cell. 181(6):1263-1275.e16. PubMed
  225. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  226. Koyama M et al. 2019. Immunity. 51(5):885-898 . PubMed
  227. Chithanathan K, et al. 2022. Biology (Basel). 11:. PubMed
  228. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  229. Erens C, et al. 2022. Biomedicines. 10:. PubMed
  230. Yang F, et al. 2021. Nat Commun. 12:3424. PubMed
  231. Kapralov AA, et al. 2020. Nat Chem Biol. 278:16. PubMed
  232. Zheng H, et al. 2021. Frontiers in Immunology. 12:645100. PubMed
  233. Han J, et al. 2015. Cancer Res . 75: 5273 - 5282. PubMed
  234. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  235. Strattan E, et al. 2020. Frontiers in Immunology. 2.131944444. PubMed
  236. Ribechini E, et al. 2017. Blood Adv. 0.699305556. PubMed
  237. Tan DQ, et al. 2019. Cell Rep. 26:2316. PubMed
  238. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  239. Aurélien Trompette et al. 2018. Immunity. 48(5):992-1005 . PubMed
RRID
AB_893233 (BioLegend Cat. No. 101227)
AB_893232 (BioLegend Cat. No. 101228)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
Go To Top Version: 2    Revision Date: 11/19/2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere

Login / Register
Remember me
Forgot your password? Reset password?
Create an Account