APC anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
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M1slash70_APC_042706
C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) APC (filled histogram) or rat IgG2b, κ APC isotype control (open histogram) (gated on total cells).
  • M1slash70_APC_042706
    C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) APC (filled histogram) or rat IgG2b, κ APC isotype control (open histogram) (gated on total cells).
Compare all formats See APC spectral data
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101211 25 µg 27€
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101212 100 µg 84€
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Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11b antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Chuang H, et al. 2014. Nat Commun. 5:4602. PubMed
  2. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  3. Chang YS, et al. 2020. Int J Mol Sci. 21:00. PubMed
  4. Chen Q, et al. 2019. Cell Stem Cell. 25(6):768-783.e6. PubMed
  5. Sun L, et al. 2021. Cancer Cell. :. PubMed
  6. Frieler RA, et al. 2017. Exp Neurol. 298:104. PubMed
  7. Combes F, et al. 2018. Neoplasia. 20:848. PubMed
  8. Lin C et al. 2019. Immunity. 50(1):137-151 . PubMed
  9. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  10. Jiang W, et al. 2017. Sci Rep. 7:6501. PubMed
  11. Schröder N, et al. 2020. J Neuroinflammation. 17:131. PubMed
  12. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  13. Lawson H, et al. 2021. Stem Cell Reports. 16:2784. PubMed
  14. Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
  15. Li F, et al. 2022. Mediators Inflamm. 2022:5782922. PubMed
  16. Hao Y, et al. 2022. Exp Ther Med. 23:350. PubMed
  17. Yang D, et al. 2022. Cell. 185:1905. PubMed
  18. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  19. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  20. Almada AE, et al. 2021. Cell Reports. 34(4):108656. PubMed
  21. Kokona D, et al. 2016. Exp Eye Res. S0014-4835(16)30499-7. PubMed
  22. Oliveira-Lima OC, et al. 2015. Immunobiology. . PubMed
  23. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  24. Paris J et al. 2019. Cell Stem Cell. 25(1):137-148 . PubMed
  25. Page N, et al. 2018. Immunity. 48:937. PubMed
  26. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  27. Sanders KA, et al. 2019. Sci Rep. 9:231. PubMed
  28. Hirata Y et al. 2018. Cell stem cell. 22(3):445-453 . PubMed
  29. Wang F, et al. 2018. Oncogenesis. 7:41. PubMed
  30. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  31. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  32. d'Errico P, et al. 2021. Nat Neurosci. Online ahead of print. PubMed
  33. Huck NA, et al. 2021. J Neurosci. 41:4349. PubMed
  34. Tang L, et al. 2021. Oncol Lett. 22:605. PubMed
  35. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  36. Clark K, et al. 2015. J Autoimmun. Available online 21 August 2015. PubMed
  37. O’Dea K, et al. 2016. PLoS One. 11:e0167801. PubMed
  38. Chen CC, et al. 2020. Cancer Cell. 37:71. PubMed
  39. Ebneter A, et al. 2017. Transl Vis Sci Technol. 10.1167/tvst.6.2.10. PubMed
  40. Chen Y, et al. 2018. EBioMedicine. 32:31. PubMed
  41. Misumi I et al. 2019. Cell Rep. 27(5):1387-1396 . PubMed
  42. Song C, et al. 2019. Nat Commun. 10:3745. PubMed
  43. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
  44. Hanhai Z, et al. 2021. Aging (Albany NY). 13:13108. PubMed
  45. Zhang J, et al. 2021. MedComm (Beijing). 2:256. PubMed
  46. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  47. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  48. Boldison J, et al. 2020. Cell Mol Immunol. 17:843. PubMed
  49. de Groot AE, et al. 2021. Prostate. 81:629. PubMed
  50. Skinner DD, et al. 2022. Front Immunol. 13:931388. PubMed
  51. Pack AD, et al. 2021. Cell Reports. 36(8):109586. PubMed
  52. Larouche JA, et al. 2021. eLife. 0.416666666666667. PubMed
  53. Yousif AS, et al. 2020. Immunity. 54(2):235-246.e5. PubMed
  54. Elbaz M, et al. 2015. Mol Oncol. 9: 906-919. PubMed
  55. Yang Y, et al. 2020. Cell Death Discov. 0.293055556. PubMed
  56. Lutzmann M, et al. 2019. Cell Rep. 28:2851. PubMed
  57. Chow MT et al. 2019. Immunity. 50(6):1498-1512 . PubMed
  58. Chattopadhyay A, et al. 2018. Sci Rep. 8:9032. PubMed
  59. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  60. Oh DS, et al. 2021. Autophagy. 17:2111. PubMed
  61. Wang Q, et al. 2020. Wound Repair Regen. 28:105. PubMed
  62. Jia G, et al. 2022. Front Cell Dev Biol. 9:796757. PubMed
  63. Rogic A, et al. 2021. Nat Commun. 12:6889. PubMed
  64. Rossi DC, et al. 2021. J Clin Invest. 131:. PubMed
  65. Castiglioni A, et al. 2015. PLoS One. 10:128094. PubMed
  66. Nasser MW, et al. 2015. Cancer Res . 75: 974-985. PubMed
  67. Liu Y, et al. 2015. Sci Rep. 5:17215. PubMed
  68. Peng J, et al. 2016. Nat Commun. 7:12029. PubMed
  69. Seita Y, et al. 2020. J Alzheimers Dis. 75:45:00. PubMed
  70. Shi L, et al. 2021. Immunity. . PubMed
  71. Jin X, et al. 2019. Mol Cell. 73:22:00. PubMed
  72. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  73. Yamashiro LH, et al. 2020. Nat Commun. 2.806944444. PubMed
  74. Fukushima T, et al. 2019. Cell Rep. 29:4144. PubMed
  75. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  76. Bae SH, et al. 2021. Theranostics. 11:2522. PubMed
  77. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  78. Kummer MP, et al. 2021. EMBO J. 40:e108662. PubMed
  79. Casali P, et al. 2021. Front Immunol. 12:761450. PubMed
  80. Xu M, et al. 2021. Front Physiol. 12:700338. PubMed
  81. Bell BJ, et al. 2022. Brain Behav Immun Health. 23:100478. PubMed
  82. Dolgova EV, et al. 2022. Int J Mol Sci. 23:. PubMed
  83. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  84. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  85. Lebratti T, et al. 2021. eLife. 10:00. PubMed
  86. Chew W, et al. 2016. Nat Methods. 13: 868-874. PubMed
  87. Oghumu S, et al. 2014. Immunology. 143: 109-119. PubMed
  88. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  89. Sive J, et al. 2015. Leukemia. . PubMed
  90. Eddens T, et al. 2015. J Immunol. 195: 185 - 193. PubMed
  91. Haas R 2013. J Immunol. 190:3100. PubMed
  92. Zhou Z, et al. 2019. Oxid Med Cell Longev. 2019:1209307. PubMed
  93. An YA et al. 2017. eLife. 6 pii: e24071. PubMed
  94. Nowak WN, et al. 2019. Mediators Inflamm. 2019:1868170. PubMed
  95. Tran L, et al. 2017. Cancer Immunol Res. 5:1141. PubMed
  96. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  97. Higa T, et al. 2022. Nat Commun. 13:1500. PubMed
  98. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  99. Syed A, et al. 2015. Infect Immun . 83: 3428-3437. PubMed
  100. Gabbita S, et al. 2015. PLoS One. 10: e0137305. PubMed
  101. Zhang Y, et al. 2020. Int J Mol Sci. 21:00. PubMed
  102. Szafran BN, et al. 2021. Chemical Research in Toxicology. 34(6):1556-1571. PubMed
  103. Dos Santos Dias L, et al. 2021. PLoS Pathog. e1009324:17. PubMed
  104. McCreedy DA et al. 2018. eNeuro. 5(4) pii: ENEURO. PubMed
  105. Yang L, et al. 2020. Cell Stem Cell. 27(1):125-136. PubMed
  106. Sato H, et al. 2020. Cell Reports. 31(5):107579. PubMed
  107. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  108. Cheng K, et al. 2021. Nat Commun. 12:2041. PubMed
  109. Donlan AN, et al. 2020. Anaerobe. 66:102275. PubMed
  110. Hug S, et al. 2021. Front Immunol. 12:642867. PubMed
  111. Xiao P, et al. 2021. JCI Insight. 6:. PubMed
  112. Yu X, et al. 2022. J Extracell Vesicles. 11:e12185. PubMed
  113. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  114. Zhou Y, et al. 2022. Nat Commun. 13:2906. PubMed
  115. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  116. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  117. Uher O, et al. 2021. Cancers (Basel). 13:. PubMed
  118. Callahan SM, et al. 2021. Curr Protoc. 1:e294. PubMed
  119. Yoshida K, et al. 2022. Sci Rep. 12:17276. PubMed
  120. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  121. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  122. Honarpisheh P, et al. 2020. J Neuroinflammation. 0.9625. PubMed
  123. Chun E, et al. 2020. Immunity. 51(5):871-884.e6.. PubMed
  124. Di Genua C, et al. 2020. Cancer Cell. 37(5):690-704.e8.. PubMed
  125. Domingos-Pereira S, et al. 2019. Cancer Immunol Res. 7:621. PubMed
  126. Hiramoto T, et al. 2018. Mol Ther. 26:1255. PubMed
  127. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  128. Topper MJ et al. 2017. Cell. 171(6):1284-1300 . PubMed
  129. Yu VWC, et al. 2017. Cell. 168:944. PubMed
  130. Ayoub M, et al. 2019. Sci Rep. 9:6348. PubMed
  131. Perdomo J, et al. 2019. Nat Commun. 10:1322. PubMed
  132. Yu Y, et al. 2019. J Clin Invest. 129:546. PubMed
  133. Colliou N, et al. 2018. Gut Microbes. 9:279. PubMed
  134. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  135. Hernández–Santos N, et al. 2018. Cell Host Microbe. 1.313194444. PubMed
  136. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  137. BÖiers C, et al. 2018. Dev Cell. 44:362. PubMed
  138. Kang SJ, et al. 2022. Food Sci Anim Resour. 42:903. PubMed
  139. Sodji QH, et al. 2022. Cancer Res Commun. 2:725. PubMed
  140. Li Z, et al. 2022. J Exp Clin Cancer Res. 41:74. PubMed
  141. Hu J, et al. 2022. Cell Mol Neurobiol. . PubMed
  142. Soto-Díaz K, et al. 2021. Front Immunol. 12:734349. PubMed
  143. Scheiblich H, et al. 2021. J Immunol. 207:2143. PubMed
  144. Shcherbina A, et al. 2020. Cell Rep. 32:107964. PubMed
  145. Miki Y, et al. 2016. J Biol Chem. 291: 15588 - 15601. PubMed
  146. Liu Y, et al. 2017. J Neurosci. 37(4):871-881. PubMed
  147. Li J, et al. 2020. Elife. 9:00. PubMed
  148. Wessel AW, et al. 2020. Nat Commun. 4.123611111. PubMed
  149. Callahan S, et al. 2020. Cell Microbiol. 22:e13210. PubMed
  150. Tang CC, et al. 2021. eLife. 10:00. PubMed
  151. Li Y, et al. 2020. Cell Stem Cell. 27(5):732-747.e7. PubMed
  152. Omori S, et al. 2021. Cell Reports. 34(6):108734. PubMed
  153. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  154. Morimura S, et al. 2021. Int J Mol Sci. :22. PubMed
  155. Peralta Ramos JM, et al. 2017. Front Immunol. 1.490277778. PubMed
  156. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  157. Xu H, et al. 2020. Immunity. 51(4):696-708.e9.. PubMed
  158. Socodato R, et al. 2020. Sci Signal. 13: . PubMed
  159. Timmons GA, et al. 2021. Front Immunol. 12:700431. PubMed
  160. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  161. Horn KJ, et al. 2022. Nat Commun. 13:3321. PubMed
  162. Lee SS, et al. 2022. Commun Biol. 5:654. PubMed
  163. Sá da Bandeira D, et al. 2022. Cell Rep. 40:111114. PubMed
  164. Grune J, et al. 2022. Nat Cardiovasc Res. 1:649. PubMed
  165. Hu J, et al. 2022. J Neuroinflammation. 19:71. PubMed
  166. Mansell E, et al. 2020. Cell Stem Cell. . PubMed
  167. Hassan AO, et al. 2021. Cell Reports. 36(4):109452. PubMed
  168. Zee BM, et al. 2021. iScience. 24(6):102651. PubMed
  169. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  170. Bayik D, et al. 2020. Cancer Discov. 1.256944444. PubMed
  171. Corrales L, et al. 2016. J Immunol. 196: 3191-3198. PubMed
  172. Koshida R, et al. 2015. Biochem Biophys Res Commun. 463: 109-115. PubMed
  173. Yu LC, et al. 2020. Front Neurol. 1.104166667. PubMed
  174. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  175. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  176. Haloul M, et al. 2019. Sci Rep. 9:14050. PubMed
  177. Booth CAG, et al. 2018. Cancer Cell. 33:274. PubMed
  178. Xu X, et al. 2018. Cell. 175:1336. PubMed
  179. Habib S, et al. 2018. Infect Immun. 86:e00019. PubMed
  180. Ishidome T et al. 2017. EBioMedicine. 22:89-99 . PubMed
  181. Zhou Z, et al. 2022. Life (Basel). 12:. PubMed
  182. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  183. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  184. Yang Z, et al. 2021. Sci Adv. 7:. PubMed
  185. Shen X, et al. 2021. Front Immunol. 12:710750. PubMed
  186. Golden TN, et al. 2022. Front Pharmacol. 12:761496. PubMed
  187. Kren N, et al. 2020. Sci Rep. 10:7390. PubMed
  188. Viengkhou B, et al. 2021. J Neuroinflammation. 18:237. PubMed
  189. Cuesta M, et al. 2016. J Immunol. 196: 2466 - 2475. PubMed
  190. Ma H, Wan S, Xia C 2016. J Leukoc Biol. 99: 1121 - 1129. PubMed
  191. Nosho S, et al. 2020. Int J Mol Sci. 21:00. PubMed
  192. Runyan CE, et al. 2020. Aging Cell. 19:00. PubMed
  193. Burns JC, et al. 2020. eLife. 9:00. PubMed
  194. Tripathi H, et al. 2020. Stem Cell Rev Rep. 0.953472222. PubMed
  195. Guldner IH, et al. 2020. Cell. 183(5):1234-1248.e25. PubMed
  196. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  197. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  198. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  199. Lu P, et al. 2021. Nat Commun. 12:1042. PubMed
  200. Bugler-Lamb AR, et al. 2021. Mol Metab. 49:101197. PubMed
  201. Zhu Y, et al. 2021. EMBO J. 40:e105320. PubMed
  202. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  203. Kim S, et al. 2021. Elife. 10:. PubMed
  204. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  205. Cilenti F, et al. 2021. Immunity. . PubMed
  206. Maruoka M, et al. 2021. Molecular Cell. 81(7):1397-1410.e9. PubMed
  207. Lee J, et al. 2020. Cell Reports. 33(13):108560. PubMed
  208. Ni J, et al. 2020. Immunity. 52(6):1075-1087.e8. PubMed
  209. Dobson HE, et al. 2020. Mucosal Immunol. 0.901388889. PubMed
  210. Cho DS, et al. 2020. J Cachexia Sarcopenia Muscle. 1.396527778. PubMed
  211. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  212. Liu Z, et al. 2020. Cell. 178(6):1509-1525.e19.. PubMed
  213. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  214. Xia P et al. 2018. Immunity. 48(4):688-701 . PubMed
  215. Nam GH, et al. 2018. Nat Commun. 9:2165. PubMed
  216. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  217. Zelter T, et al. 2022. EMBO Rep. 23:e53641. PubMed
  218. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  219. Otvos B, et al. 2021. Clin Cancer Res. 27:2038. PubMed
  220. Tapia-Abellán A, et al. 2021. Sci Adv. 7:eabf4468. PubMed
  221. Ye X, et al. 2021. Cancer Biol Med. Online ahead of print. PubMed
  222. Huang J, et al. 2014. J Immunol. 192:1972. PubMed
  223. Xiong X, et al. 2015. Stroke. 46: 2271-2276. PubMed
  224. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  225. Alam Z, et al. 2020. Cell Rep. 107825:31. PubMed
  226. Sun J et al. 2018. Cell stem cell. 23(3):355-369 . PubMed
  227. Goldstein JM et al. 2019. Cell reports. 27(4):1254-1264 . PubMed
  228. Ford J, et al. 2019. Front Immunol. 2.502083333. PubMed
  229. Ge C, et al. 2020. Cell Reports. 29(13):4236-4244.e3.. PubMed
  230. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  231. Yang Y, et al. 2020. Cell Death Discov. 6:62. PubMed
  232. Li W, et al. 2021. Cell Transplant. 30:9636897211004090. PubMed
  233. Wüthrich M, et al. 2021. MBio. 12:e0201821. PubMed
  234. Vasudevan SO, et al. 2022. Cell Rep. 39:110755. PubMed
  235. Wolf SJ, et al. 2022. JCI Insight. 7:. PubMed
  236. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  237. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  238. Lowe PP, et al. 2020. J Neuroinflammation. 0.913888889. PubMed
  239. León-Cabrera S, et al. 2014. Int J Biol Sci. 9 948 . PubMed
  240. Johansson J, et al. 2013. J Neurosci. 33:16016. PubMed
  241. Hohsfield LA, et al. 2020. J Neuroinflammation. 0.902083333. PubMed
  242. Horn LA, et al. 2017. Oncotarget. 8:57964. PubMed
  243. Tang Y, et al. 2019. Nat Commun. 10:4157. PubMed
  244. Metidji A et al. 2018. Immunity. 49(2):353-362 . PubMed
  245. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  246. Nenasheva T, et al. 2017. PLoS One. 12(6):e0178983. PubMed
  247. Howard ZM, et al. 2022. JCI Insight. 7:. PubMed
  248. Gavini CK, et al. 2022. J Neuroinflammation. 19:57. PubMed
  249. McCallion A, et al. 2022. Front Immunol. 13:961599. PubMed
  250. Wang S, et al. 2021. Commun Biol. 22:. PubMed
  251. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  252. Ha TC, et al. 2020. Hum Gene Ther. 32:458. PubMed
  253. Gorina R, et al. 2014. J Immunol. 192:324. PubMed
  254. Liu Y, et al. 2015. BioMed Res Int. 2015 563425. PubMed
  255. Choi J, et al. 2015. PLoS One. 10: e0138592. PubMed
  256. Jaako P, et al. 2016. Leukemia. 10.1038/leu.2016.159. PubMed
  257. Kumari P, et al. 2021. Cell Reports. 35(3):109012. PubMed
  258. Wilson ZS, et al. 2020. Sci Rep. 10:2142. PubMed
  259. Uribe-Herranz M, et al. 2018. JCI Insight. 3. PubMed
  260. Vásquez M, et al. 2019. J Immunol. 203:696. PubMed
  261. Ohgomori T et al. 2019. J Comp Neurol. 528(1):14-31 . PubMed
  262. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  263. Di Genua C, et al. 2019. Haematologica. 104:2215. PubMed
  264. Scheiblich H, et al. 2021. Cell. 184:5089. PubMed
  265. Deng Q, et al. 2021. Gut Microbes. 13:1. PubMed
  266. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  267. Woodring T, et al. 2022. iScience. 25:104934. PubMed
  268. Yang YS, et al. 2022. Nat Commun. 13:6175. PubMed
  269. Asadi Shahmirzadi A, et al. 2020. Cell Metabolism. 32(3):447-456.e6. PubMed
  270. Vaibhav K, et al. 2020. Sci Adv. 6:eaax8847. PubMed
  271. Prislovsky A, Strom T 2013. Exp Hematol. 41:789. PubMed
  272. Kajiwara C, et al. 2018. J Immunol. 200:623. PubMed
  273. Gomes T, et al. 2019. Front Immunol. 10:2088. PubMed
  274. Liu X, et al. 2021. Int J Med Sci. 18:3125. PubMed
  275. Friker LL, et al. 2020. Cell Rep. 30:3743. PubMed
  276. Chen F, et al. 2021. J Cell Mol Med. 25:11039. PubMed
  277. Howard ZM, et al. 2021. Am J Pathol. 191:730. PubMed
  278. Luciunaite A, et al. 2020. J Neurochem. 155:650. PubMed
  279. Pi J, et al. 2022. J Nanobiotechnology. 20:36. PubMed
  280. Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
  281. van Geffen C, et al. 2021. Front Immunol. 12:695933. PubMed
  282. Milich LM, et al. 2021. J Exp Med. 218:. PubMed
  283. Takeda K, et al. 2014. Am J Pathol. 184:686. PubMed
  284. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  285. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  286. Messerer DAC, et al. 2020. Front Immunol. 11:571992. PubMed
  287. Markworth JF, et al. 2020. JCI Insight. 5:00. PubMed
  288. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  289. Chung S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. L921:318. PubMed
  290. Steinkühler J, et al. 2018. J Cell Sci. 132. PubMed
  291. Haruwaka K, et al. 2019. Nat Commun. 4.455555556. PubMed
  292. Ireland L, et al. 2020. Front Immunol. 11:297. PubMed
  293. Ombrato L, et al. 2021. Nat Protoc. 16:872. PubMed
  294. Kelley WJ, et al. 2022. JCI Insight. :. PubMed
  295. Smith KJ, et al. 2022. PLoS Biol. 20:e3001554. PubMed
  296. Jia Y, et al. 2022. Cell Discov. 8:21. PubMed
  297. Gao P, et al. 2021. Nat Commun. 1194:12. PubMed
  298. Ubags ND, et al. 2021. J Allergy Clin Immunol. 1049:147. PubMed
  299. Hara T, et al. 2021. Cancer Cell. 39(6):779-792.e11. PubMed
  300. Riedel SS, et al. 2021. Molecular Cell. 81(11):2332-2348.e9. PubMed
  301. Simoni L, et al. 2020. Cell Rep. 33:108330. PubMed
  302. Fukasawa K, et al. 2016. Sci Rep. 6:30918. PubMed
  303. Andresen L, et al. 2016. PLoS One. 11: 0148428. PubMed
  304. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  305. Jiang Y, et al. 2015. MBio. 6: e01426-15. PubMed
  306. Shi Y, et al. 2015. Mol Immunol. 66: 208-215. PubMed
  307. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  308. Kunishita Y, et al. 2020. Front Immunol. 11:98. PubMed
  309. Säwen P et al. 2018. eLife. 7 pii: e41258. PubMed
  310. Nguyen HX et al. 2017. J Neurosci. 37(38):9269-9287 . PubMed
  311. Schroder WA, et al. 2019. Sci Rep. 9:12421. PubMed
  312. Wang C, et al. 2018. Sci Transl Med. 10. PubMed
  313. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  314. Fan HH, et al. 2021. Methods Mol Biol. 2276:203. PubMed
  315. Chavez JS, et al. 2022. Cells. 11:. PubMed
  316. Shen L, et al. 2021. Cell Metabolism. 33(5):971-987.e6. PubMed
  317. Thurlow LR, et al. 2018. Cell Host Microbe. 24:261. PubMed
  318. Petriello MC, et al. 2018. Toxicol Sci. 162:548. PubMed
  319. Hilt ZT, et al. 2019. JCI Insight. 4:5. PubMed
  320. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  321. Boguslawski KM, et al. 2020. Sci Adv. 6:eaax7515. PubMed
  322. Zhang B, et al. 2021. Nature. 599:471. PubMed
  323. Jones GS, et al. 2020. mSphere. 5:. PubMed
  324. Xiao M, et al. 2022. Mol Oncol. 16:1026. PubMed
  325. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  326. Zha ZX, et al. 2022. Acta Pharmacol Sin. :. PubMed
  327. Zhang H, et al. 2022. Commun Biol. 5:916. PubMed
  328. Li J, et al. 2022. Nat Commun. 13:1481. PubMed
  329. Du Z, et al. 2020. J Allergy Clin Immunol. . PubMed
  330. Li X, et al. 2021. Cell Reports. 36(8):109607. PubMed
  331. Li J, et al. 2021. eLife. 10:00. PubMed
  332. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  333. Xiang W, et al. 2020. Signal Transduct Target Ther. 0.374305556. PubMed
  334. Xie Y, et al. 2020. Endocrinology. 161:00:00. PubMed
  335. Hohmann A, et al. 2016. Nat Chem Biol. 10.1038/nchembio.2115. PubMed
  336. Ramos-Sevillano E, et al. 2016. PLoS One. 12: 1005500. PubMed
  337. Kolan S, et al. 2015. PLoS One. 10: 0134113. PubMed
  338. Iwata-Yoshikawa N, et al. 2014. J Virol. 88:8597. PubMed
  339. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  340. Guenther C, et al. 2019. Front Immunol. 10:1138. PubMed
  341. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  342. Li B, et al. 2019. Oncogenesis. 8:17. PubMed
  343. Omenetti S, et al. 2019. Immunity. 51:77. PubMed
  344. Yáñez A et al. 2017. Immunity. 47(5):890-902 . PubMed
  345. Han J, et al. 2022. Cell Discov. 8:122. PubMed
  346. Schmidts A, et al. 2020. J Immunother Cancer. 8:. PubMed
  347. Sethuraman SN, et al. 2020. Theranostics. 10:3397. PubMed
  348. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
  349. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  350. Zhang J, et al. 2021. Stem Cell Res Ther. 12:579. PubMed
  351. Chang MH, et al. 2021. Cell Rep. 37:109902. PubMed
  352. Ren X, et al. 2021. Cell Death Dis. 12:484. PubMed
RRID
AB_312794 (BioLegend Cat. No. 101211)
AB_312795 (BioLegend Cat. No. 101212)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC, IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC, CyTOF®, IP, IHC-F, ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC, IHC-F, 3D IHC, SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC, 3D IHC
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC, ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC, CyTOF®, IP, Block, Depletion, IHC-F, ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC, CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F, FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • APC anti-mouse/human CD11b

  • Biotin anti-mouse/human CD11b

  • FITC anti-mouse/human CD11b

  • PE anti-mouse/human CD11b

  • PE/Cyanine5 anti-mouse/human CD11b

  • Purified anti-mouse/human CD11b

  • PE/Cyanine7 anti-mouse/human CD11b

  • Alexa Fluor® 488 anti-mouse/human CD11b

  • Alexa Fluor® 647 anti-mouse/human CD11b

  • Alexa Fluor® 700 anti-mouse/human CD11b

  • Pacific Blue™ anti-mouse/human CD11b

  • APC/Cyanine7 anti-mouse/human CD11b

  • PerCP/Cyanine5.5 anti-mouse/human CD11b

  • PerCP anti-mouse/human CD11b

  • Brilliant Violet 421™ anti-mouse/human CD11b

  • Brilliant Violet 570™ anti-mouse/human CD11b

  • Brilliant Violet 605™ anti-mouse/human CD11b

  • Brilliant Violet 650™ anti-mouse/human CD11b

  • Brilliant Violet 711™ anti-mouse/human CD11b

  • Brilliant Violet 785™ anti-mouse/human CD11b

  • Brilliant Violet 510™ anti-mouse/human CD11b

  • Ultra-LEAF™ Purified anti-mouse/human CD11b

  • Purified anti-mouse/human CD11b (Maxpar® Ready)

  • Alexa Fluor® 594 anti-mouse/human CD11b

  • PE/Dazzle™ 594 anti-mouse/human CD11b

  • APC/Fire™ 750 anti-mouse/human CD11b

  • TotalSeq™-A0014 anti-mouse/human CD11b

  • Brilliant Violet 750™ anti-mouse/human CD11b

  • TotalSeq™-B0014 anti-mouse/human CD11b

  • TotalSeq™-C0014 anti-mouse/human CD11b

  • Spark NIR™ 685 anti-mouse/human CD11b

  • PE/Fire™ 640 anti-mouse/human CD11b

  • Spark YG™ 593 anti-mouse/human CD11b

  • Spark YG™ 570 anti-mouse/human CD11b

  • PE/Fire™ 810 anti-mouse/human CD11b

  • APC/Fire™ 810 anti-mouse/human CD11b Antibody

  • Spark Blue™ 550 anti-mouse/human CD11b

  • Spark UV™ 387 anti-mouse/human CD11b

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