- W15145C (See other available formats)
- Regulatory Status
- Other Names
- Mouse IgG2a, κ
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- Product Citations
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Toll-like receptors are type I transmembrane signaling receptors which are critical for the innate host defense to pathogens. Toll-like receptor 2 (TLR2), known as CD282, has been identified as a receptor that is central to the innate immune system's response to lipoproteins of Gram-negative bacteria and Gram-positive bacteria, as well as a receptor for peptidoglycan and lipoteichoic acid and other bacterial cell membrane products.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Full length human TLR2 transfected cells
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
AB_2927936 (BioLegend Cat. No. 392311)
AB_2927936 (BioLegend Cat. No. 392312)
- IL-1R superfamily, TLR family, type 1 transmebrane protein, 90kD
Monocytes, Granulocytes, endothelial and epithelial cells
- Activates innate host defense against bacterial pathogens
- Microbial lipoproteins, peptidoglycans, lipoteichoic acid
- Cell Type
- Endothelial cells, Epithelial cells, Granulocytes, Monocytes
- Biology Area
- Molecular Family
- CD Molecules, Toll Like Receptors
- Antigen References
1. Lien E, et al. 1999. J. Biol. Chem. 274:33419.
2. Lien E, et al. 2001. J. Biol. Chem. 276:1873.
3. Sabroe I, et al. 2002. J. Immunol. 168:4701.
- Gene ID
- 7097 View all products for this Gene ID
- View information about CD282 on UniProt.org
Related Pages & Pathways
Other FormatsView All CD282 Reagents Request Custom Conjugation
|Purified anti-human CD282 (TLR2)||W15145C||FC|
|FITC anti-human CD282 (TLR2)||W15145C||FC|
|APC anti-human CD282 (TLR2)||W15145C||FC|
|PE anti-human CD282 (TLR2)||W15145C||FC|
|PE/Cyanine7 anti-human CD282 (TLR2)||W15145C||FC|
|PE/Dazzle™ 594 anti-human CD282 (TLR2)||W15145C||FC|
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