APC anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
publications
30-F11_APC_090507
C57BL/6 mouse splenocytes stained with 30-F11 APC
  • 30-F11_APC_090507
    C57BL/6 mouse splenocytes stained with 30-F11 APC
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
103111 25 µg 27€
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103112 100 µg 76€
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Gavin KM, et al. 2018. Front Endocrinol (Lausanne). 9:276. PubMed
  2. Wang L, et al. 2018. Bone Res. 6:22. PubMed
  3. Cha JH et al. 2018. Molecular cell. 71(4):606-620 . PubMed
  4. Haimon Z et al. 2018. Nature immunology. 19(6):636-644 . PubMed
  5. Ying W, et al. 2019. Cell Metab. 29:457. PubMed
  6. Strickley JD, et al. 2019. Nature. 575:519. PubMed
  7. Jiang Z, et al. 2021. J Clin Invest. 131: . PubMed
  8. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  9. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  10. Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
  11. Nigam S, et al. 2020. Mol Imaging Biol. 22:685. PubMed
  12. Yang D, et al. 2022. Cell. 185:1905. PubMed
  13. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  14. Mourao L, et al. 2019. Sci Rep. 0.991666667. PubMed
  15. Oetjen LK et al. 2017. Cell. 171(1):217-228 . PubMed
  16. Testini C, et al. 2019. EMBO Rep. 20:e47845. PubMed
  17. Gao Q, et al. 2019. J Exp Med. 216:688. PubMed
  18. Shavit Stein E, et al. 2018. Neural Plast. 2018:7692182. PubMed
  19. Bouchareychas L, et al. 2021. iScience. 24(8):102847. PubMed
  20. Almada AE, et al. 2021. Cell Reports. 34(4):108656. PubMed
  21. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  22. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  23. Jaiswal AK, et al. 2020. Immunobiology. 225:151956. PubMed
  24. Cayre S, et al. 2020. Development. 147:00:00. PubMed
  25. Díaz NM, et al. 2020. Invest Ophthalmol Vis Sci. 61:37:00. PubMed
  26. Karlen SJ, et al. 2018. J Neuroinflammation. 15:344. PubMed
  27. Du Q, et al. 2019. Front Microbiol. 10:2050. PubMed
  28. Kang I, et al. 2012. Blood. 119:3295. PubMed
  29. Rosa FF, et al. 2020. Bio Protoc. 10:e3619. PubMed
  30. Wang Y, et al. 2021. J Bone Oncol. 30:100386. PubMed
  31. Lu L, et al. 2022. Sci Rep. 12:931. PubMed
  32. Parhiz H, et al. 2022. J Control Release. 344:50. PubMed
  33. Ahmed M, et al. 2016. Development. 143: 1663 - 1673. PubMed
  34. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  35. Lim JT, et al. 2020. Mol Cancer Ther. 1809:19. PubMed
  36. Engelbrecht E, et al. 2020. eLife. 9:e52690.. PubMed
  37. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  38. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  39. Chen J, et al. 2022. Nat Commun. 13:6759. PubMed
  40. Wang S, et al. 2022. Front Immunol. 13:869061. PubMed
  41. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  42. Barwe SP, et al. 2022. J Clin Med. 11:. PubMed
  43. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  44. Yu X, et al. 2021. Nature. 594:560. PubMed
  45. Sato S, et al. 2021. Int J Mol Sci. 22:. PubMed
  46. Oliva Chávez AS, et al. 2021. Nat Commun. 12:3696. PubMed
  47. Yanagida K, et al. 2020. Dev Cell. 779:52. PubMed
  48. Hirano KI, et al. 2021. eLife. 0.416666666666667. PubMed
  49. Larouche JA, et al. 2021. eLife. 0.416666666666667. PubMed
  50. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  51. Barberio AE, et al. 2020. ACS Nano. 14:11238. PubMed
  52. Chiche A, et al. 2016. Oncogene. 10.1038/onc.2016.396. PubMed
  53. Eastman A, et al. 2016. J Immunol . 194: 5999-6010. PubMed
  54. Jin X, et al. 2019. Mol Cell. 73:22:00. PubMed
  55. Duarte N, et al. 2018. Hepatol Commun. 0.833333333. PubMed
  56. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  57. Romagnoli M, et al. 2020. Development. 147:. PubMed
  58. Li Q, et al. 2021. Brain Behav Immun. 94:437. PubMed
  59. Wang X, et al. 2022. Nat Aging. 2:155. PubMed
  60. Wang T, et al. 2020. Blood Sci. 2:79. PubMed
  61. Strunz M, et al. 2020. Nat Commun. 2.929861111. PubMed
  62. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  63. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  64. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  65. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  66. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  67. Motoyama S, et al. 2020. Cells. :9. PubMed
  68. Pelletier A, et al. 2012. J Immunol. 188:5561. PubMed
  69. Herting CJ, et al. 2019. Brain. 142:3834. PubMed
  70. Romagnoli M, et al. 2019. Stem Cell Reports. 1.077083333. PubMed
  71. Ning X, et al. 2019. Mol Cell. 74:19. PubMed
  72. De S, et al. 2018. Development. 145. PubMed
  73. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  74. Mauduit O, et al. 2022. Front Immunol. 13:1011125. PubMed
  75. Chen Z, et al. 2022. Theranostics. 12:6242. PubMed
  76. Xu X, et al. 2021. J Nanobiotechnology. 19:376. PubMed
  77. Bourn JR, et al. 2021. Cancer Lett. 503:75. PubMed
  78. Khateb M, et al. 2022. Cell Rep. 40:111219. PubMed
  79. Xu Q, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  80. Liu K, et al. 2022. Theranostics. 12:639. PubMed
  81. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  82. Lv H, et al. 2020. Cell Metabolism. 33(1):110-127.e5. PubMed
  83. Amouyal C, et al. 2020. EBioMedicine. 58:102895. PubMed
  84. Liu L, et al. 2015. Neurol Neuroimmunol Neuroinflamm. 2: 174. PubMed
  85. Hyatt L, et al. 2014. PLoS One. 9:109072. PubMed
  86. An J,et al. 2017. Sci Rep.. 10.1038/s41598-017-13629-0. PubMed
  87. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  88. Maston LD, et al. 2017. Am J Physiol Lung Cell Mol Physiol. 312:L609. PubMed
  89. Bresson L, et al. 2018. Development. 145. PubMed
  90. Charmsaz S, et al. 2017. Leukemia. 31:1779. PubMed
  91. Sambasivan R, et al. 2011. Development. 138:3647. PubMed
  92. Hu EY, et al. 2021. Blood Adv. 5:3152. PubMed
  93. Palathingal Bava E, et al. 2022. JCI Insight. 7:. PubMed
  94. Lafkas D, et al. 2013. J Cell Biol. 203:47. PubMed
  95. Ma S, et al. 2021. Cell Reports. 34(6):108726. PubMed
  96. Ankawa R, et al. 2021. Developmental Cell. . PubMed
  97. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
  98. Xiao P, et al. 2019. J Exp Med. 216:337. PubMed
  99. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  100. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  101. Zheng B, et al. 2018. J Hematol Oncol. 11:16. PubMed
  102. Pal B, et al. 2017. Nat Commun.. 10.1038/s41467-017-01560-x. PubMed
  103. Fischer A, et al. 2022. Nat Immunol. 23:518. PubMed
  104. Hu J, et al. 2022. Cell Mol Neurobiol. . PubMed
  105. Chen L, et al. 2021. Cell Death Differ. 28:1880. PubMed
  106. Shcherbina A, et al. 2020. Cell Rep. 32:107964. PubMed
  107. Wu J, et al. 2020. Immunity. 53:115. PubMed
  108. Frii J, et al. 2021. Immunity. 54(5):1002-1021.e10. PubMed
  109. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  110. Yuan Z, et al. 2018. Emerg Microbes Infect. 7:59. PubMed
  111. Hou M, et al. 2020. Stem Cell Res Ther. 11:55. PubMed
  112. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  113. Hanasoge Somasundara AV, et al. 2021. Cell Rep. 37:110099. PubMed
  114. Thinard R, et al. 2022. Pharmaceutics. 14:. PubMed
  115. Yang H, et al. 2022. Nutrients. 14:. PubMed
  116. Hu J, et al. 2022. J Neuroinflammation. 19:71. PubMed
  117. Pezoldt J, et al. 2022. Nat Commun. 13:7227. PubMed
  118. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  119. Dudek KA, et al. 2020. Proc Natl Acad Sci U S A. 117:3326. PubMed
  120. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  121. Crooks SD, et al. 2022. Immunohorizons. 6:705. PubMed
  122. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  123. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  124. Koren E, et al. 2022. Nat Commun. 13:4628. PubMed
  125. Bauer T, et al. 2021. Life (Basel). 11:. PubMed
  126. Li P, et al. 2022. EMBO Mol Med. 14:e14511. PubMed
  127. Zuo S, et al. 2021. J Immunother Cancer. 9:. PubMed
  128. Myerson JW, et al. 2021. Nat Nanotechnol. Online ahead of print. PubMed
  129. Jia Q, et al. 2021. Theranostics. 4699:11. PubMed
  130. Paiva-Oliveira E, et al. 2017. Histochem Cell Biol. 10.1007/s00418-017-1556-6. PubMed
  131. Kaur A, et al. 2019. Cancer Discov. 9:64. PubMed
  132. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  133. Zhou G, et al. 2019. FASEB J. 33:11396. PubMed
  134. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  135. Yang Y, et al. 2022. Elife. 11:. PubMed
  136. Dey S, et al. 2020. J Immunother Cancer. 8:. PubMed
  137. Zhang Q, et al. 2022. Nat Commun. 13:2406. PubMed
  138. Scur M, et al. 2022. Nat Commun. 13:7272. PubMed
  139. Wang C, et al. 2011. Hepatology. 55:108. PubMed
  140. Sim S, et al. 2016. PLoS One. 11: 0152485. PubMed
  141. Mangum L, et al. 2016. Toxicol Sci. 150: 169 - 177. PubMed
  142. Mizuno T, et al. 2017. Sci Rep. 7:42714. PubMed
  143. Nosho S, et al. 2020. Int J Mol Sci. 21:00. PubMed
  144. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  145. Yamada KJ, et al. 2020. PLoS Pathog. 16:e1008354. PubMed
  146. Tu WL, et al. 2018. Am J Pathol. 188:2688. PubMed
  147. Chiche A, et al. 2019. Breast Cancer Res. 21:13. PubMed
  148. Feng J,et al. 2017. Nat Commun. . 10.1038/s41467-017-01056-8. PubMed
  149. Limbad C, et al. 2022. iScience. 25:103848. PubMed
  150. Chiang HY, et al. 2022. Nat Commun. 13:874. PubMed
  151. Aguilera M, et al. 2021. Int J Mol Sci. 22:. PubMed
  152. Xi W, et al. 2021. Stem Cell Res Ther. 167:12. PubMed
  153. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  154. Dawson CA, et al. 2021. Nature Protocols. 16(4):1907-1935. PubMed
  155. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  156. Echevarría-Vargas IM, et al. 2018. EMBO Mol Med. 10:e8446. PubMed
  157. Shi R, et al. 2019. J Cancer. 10:367. PubMed
  158. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  159. Usmani SM et al. 2019. Cell host & microbe. 25(1):73-86 . PubMed
  160. Zasłona Z, et al. 2017. Am J Physiol Lung Cell Mol Physiol. 312:L855. PubMed
  161. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  162. Liu D, et al. 2020. Front Pharmacol. 11:204. PubMed
  163. Dion-Albert L, et al. 2022. Nat Commun. 13:164. PubMed
  164. Long JT, et al. 2022. Elife. 11:. PubMed
  165. Zhang Z, et al. 2021. Exp Dermatol. 30:102. PubMed
  166. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  167. Garcia-Bonilla L, et al. 2014. J Immunol. 193:2531. PubMed
  168. Ding X, et al. 2015. J Immunol. 194:4251. PubMed
  169. Wang L, et al. 2015. Cancer Immunol Res. 3: 1030-1041. PubMed
  170. Mueller A, et al. 2016. Nature. 540:276-279. PubMed
  171. Perry JL, et al. 2020. ACS Nano. 5.583333333. PubMed
  172. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  173. Penkert RR, et al. 2020. Obesity (Silver Spring). 1631:28. PubMed
  174. Mori A, et al. 2021. Cells. :10. PubMed
  175. Cai B, et al. 2020. Cell Metabolism. 31(2):406-421.e7.. PubMed
  176. Lu Y, et al. 2020. Immunity. 52:782. PubMed
  177. Toyama K, et al. 2018. Arterioscler Thromb Vasc Biol. 38:1392. PubMed
  178. Qiao S, et al. 2019. J Neuroinflammation. 16:4. PubMed
  179. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  180. Murdock BJ, et al. 2021. JCI Insight. 6:. PubMed
  181. Yang Y, et al. 2021. Cell Reports. 34(10):108822. PubMed
  182. Taya M, et al. 2020. Endocr Relat Cancer. 27:261. PubMed
  183. Carmody C et al. 2019. Endocrinology. 160(5):1205-1222 . PubMed
  184. Fu NY, et al. 2018. Dev Cell. 47:629. PubMed
  185. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  186. Yeo SK, et al. 2020. eLife. 9:e58810.. PubMed
  187. Zhang J, et al. 2022. Biomater Res. 26:44. PubMed
  188. Hoover AR, et al. 2022. Clin Transl Med. 12:e937. PubMed
  189. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  190. Elias S, et al. 2015. PLoS Biol. 13:1002142. PubMed
  191. Deng P, et al. 2021. Cell Stem Cell. 28(6):1057-1073.e7. PubMed
  192. Nasser H, et al. 2020. Cell Death Discov. 0.29375. PubMed
  193. Sroor HM, et al. 2019. Sci Rep. 9:20217. PubMed
  194. Chen PY, et al. 2019. Nat Metab. 0.675. PubMed
  195. Cao Y, et al. 2019. Nat Commun. 10:1280. PubMed
  196. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  197. Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
  198. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  199. Porrello A, et al. 2018. Nat Commun. 9:1988. PubMed
  200. Cai T, et al. 2022. Nat Commun. 13:2228. PubMed
  201. Kim KS, et al. 2022. JCI Insight. 7:. PubMed
  202. Zhang T, et al. 2020. JCI Insight. 5:00. PubMed
  203. Ortiz A, et al. 2019. Cancer Cell. 35:33:00. PubMed
  204. Ouadah Y, et al. 2019. Cell. 179:403. PubMed
  205. Piotrowski AF, et al. 2018. Oncoimmunology. 7:e1445951. PubMed
  206. Sarshad AA, et al. 2018. Mol Cell. 71:1040. PubMed
  207. Gopalakrishnapillai A, et al. 2021. Cancers (Basel). 13:. PubMed
  208. Liu G, et al. 2022. Theranostics. 12:2248. PubMed
  209. Arora S, et al. 2021. Med (N Y). 2:938. PubMed
  210. Li H, et al. 2022. iScience. 25:104481. PubMed
  211. Cayre S, et al. 2020. Development. . PubMed
  212. Endo-Umeda K, et al. 2021. Sci Rep. 11:22595. PubMed
  213. Pal B, et al. 2021. Breast Cancer Res. 23:69. PubMed
  214. Maller O, et al. 2020. Nat Mater. 20:548. PubMed
  215. Saber M, et al. 2020. Eur J Neurosci. 52:2791. PubMed
  216. Vaas M, et al. 2016. J Cereb Blood Flow Metab. 10.1177/0271678X16676825. PubMed
  217. Wong J, et al. 2016. Sci Signal. 9: ra103. PubMed
  218. Yuan Z, et al. 2016. J Virol. 90: 7728 - 7739. PubMed
  219. Garcia-Bonilla L, et al. 2015. J Neurosci. 35: 14783 - 14793. PubMed
  220. Jiang Y, et al. 2015. MBio. 6: e01426-15. PubMed
  221. Roberts L, et al. 2014. Infect Immun . 82:2504. PubMed
  222. Su M, et al. 2018. Immunol Cell Biol. 9:2448. PubMed
  223. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  224. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  225. Qu Y, et al. 2020. Cell Reports. 32(1):107873. PubMed
  226. Hu Y, et al. 2021. J Nanobiotechnology. 19:416. PubMed
  227. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  228. Jaeger N, et al. 2020. Cell Rep. 33:108331. PubMed
  229. Koh BI, et al. 2020. Nat Commun. 3.143055556. PubMed
  230. Ren D, et al. 2020. Am J Cancer Res. 2851:10. PubMed
  231. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  232. Quijano-Rubio A, et al. 2022. Nat Biotechnol. Online ahead of print. PubMed
  233. Scheyltjens I, et al. 2022. Nat Protoc. 17:2354. PubMed
  234. Liu C, et al. 2022. Nat Commun. 13:1989. PubMed
  235. Saber M, et al. 2021. J Neurotrauma. 38:2862. PubMed
  236. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  237. Okubo A, et al. 2021. Int J Mol Sci. 23:. PubMed
  238. Deets KA, et al. 2021. Elife. 10:. PubMed
  239. Murray CW, et al. 2022. Nat Commun. 13:1090. PubMed
  240. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  241. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  242. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  243. Dai B, et al. 2021. Cell Reports Medicine. 2(8):100381. PubMed
  244. Bravo JI, et al. 2021. STAR Protocols. 2(2):100406. PubMed
  245. Chng S, et al. 2016. Sci Rep. 6: 23820. PubMed
RRID
AB_312976 (BioLegend Cat. No. 103111)
AB_312977 (BioLegend Cat. No. 103112)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC, IHC-F, CyTOF®, IP, CMCD, IHC, WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC, SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC, ICC, IHC, 3D IHC, SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC, SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F, FC, 3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC, SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC, CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC, CyTOF®, IP, CMCD, IHC, WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Go To Top Version: 2    Revision Date: 05/14/2013

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • APC anti-mouse CD45

  • Biotin anti-mouse CD45

  • FITC anti-mouse CD45

  • PE anti-mouse CD45

  • PE/Cyanine5 anti-mouse CD45

  • Purified anti-mouse CD45

  • PE/Cyanine7 anti-mouse CD45

  • APC/Cyanine7 anti-mouse CD45

  • Alexa Fluor® 488 anti-mouse CD45

  • Alexa Fluor® 647 anti-mouse CD45

  • Pacific Blue™ anti-mouse CD45

  • Alexa Fluor® 700 anti-mouse CD45

  • PerCP/Cyanine5.5 anti-mouse CD45

  • PerCP anti-mouse CD45

  • Alexa Fluor® 594 anti-mouse CD45

  • Brilliant Violet 421™ anti-mouse CD45

  • Brilliant Violet 570™ anti-mouse CD45

  • Brilliant Violet 510™ anti-mouse CD45

  • Brilliant Violet 605™ anti-mouse CD45

  • Purified anti-mouse CD45 (Maxpar® Ready)

  • PE/Dazzle™ 594 anti-mouse CD45

  • Brilliant Violet 711™ anti-mouse CD45

  • Brilliant Violet 785™ anti-mouse CD45

  • Brilliant Violet 650™ anti-mouse CD45

  • APC/Fire™ 750 anti-mouse CD45

  • Brilliant Violet 750™ anti-mouse CD45

  • TotalSeq™-A0096 anti-mouse CD45

  • TotalSeq™-B0096 anti-mouse CD45

  • Ultra-LEAF™ Purified anti-mouse CD45

  • Spark Blue™ 550 anti-mouse CD45

  • Spark NIR™ 685 anti-mouse CD45

  • TotalSeq™-C0096 anti-mouse CD45

  • Spark YG™ 570 anti-mouse CD45

  • PE/Fire™ 640 anti-mouse CD45

  • APC/Fire™ 810 anti-mouse CD45

  • PE/Fire™ 700 anti-mouse CD45

  • Spark Violet™ 538 anti-mouse CD45

  • Spark YG™ 593 anti-mouse CD45

  • Spark Blue™ 574 anti-mouse CD45 Antibody

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