- CBR-IC2/2 (See other available formats)
- Regulatory Status
- V BP363
- Other Names
- Intercellular Adhesion Molecule-2, ICAM-2
- Mouse IgG2a, κ
- Ave. Rating
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- Product Citations
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CD102 is a 55 kD type I transmembrane glycoprotein, belongs to immunoglobulin superfamily, also known as Intercellular Adhesion Molecule-2, or ICAM-2. CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and in costimulation of immune response. CD102 is a counter receptor of LFA-1 (CD11a/CD18), DC-SIGN and MAC-1.Product Details
- Verified Reactivity
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Host Species
- ICAM-2 cDNA transfected COS cells
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
IP, IHC-F - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications: immunoprecipitation(1), blocking the interaction between ICAM-2 and LFA-1(1), immunohistochemical staining(2) of frozen tissue sections
(PubMed link indicates BioLegend citation)
- DeFougerolles AR,et al.1991.J. Exp.Med.174:253.
- Van Herpen CML,et al.2005.Clin. Cancer Res.11:1899
- Product Citations
AB_1134245 (BioLegend Cat. No. 328502)
- 55 kD type I transmembrane glycoprotein, Ig superfamily
Vascular endothelial cells, lymphocytes, monocytes, platelets
- Adhesion, costimulation
- LFA-1, DC-SIGN, MAC-1
- Cell Type
- Endothelial cells, Lymphocytes, Monocytes, Platelets
- Biology Area
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
1.Weber KSC, et al.2004.Inflammation.28:177.
2.Barclay A, et al.1997 The Leukoycte Antigen FactsbookAcademic Press.
3. Casasnovas JM, et al.1999.P. Natl. Acad. Sci. USA96:3017.
4. Diamonds MS, et al.1990. J. Cell Biol.111:3129.
- Gene ID
- 3384 View all products for this Gene ID
- View information about CD102 on UniProt.org
Related Pages & Pathways
Other FormatsView All CD102 Reagents Request Custom Conjugation
|Purified anti-human CD102 (ICAM-2)||CBR-IC2/2||FC,IP,IHC-F|
|PE anti-human CD102 (ICAM-2)||CBR-IC2/2||FC|
|FITC anti-human CD102 (ICAM-2)||CBR-IC2/2||FC|
|TotalSeq™-A0244 anti-human CD102 (ICAM-2)||CBR-IC2/2||PG|
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