PE anti-human MSC (W7C6) Antibody

Pricing & Availability
Clone
W7C6 (See other available formats)
Regulatory Status
RUO
Other Names
Mesenchymal Stem Cells (MSC), Leukocyte Associated Antigen (LAR)
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
W7C6_PE_A_020808
Human cervical cancer cell line, HeLa, stained with W7C6 PE
  • W7C6_PE_A_020808
    Human cervical cancer cell line, HeLa, stained with W7C6 PE
  • W7C6_PE_B_020808
    Human bone marrow-derived mesenchymal stem cells stained with W7C6 PE
See PE spectral data
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327606 100 tests 286 CHF
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Description

The W7C6 antibody was generated by immunization with Weri-RB-1 cells. It reacts with mesenchymal stem cells and some tested neoplastic cell lines (HT29, Hela, MCF-7, REH). Further studies have shown that W7C6 antigen is identical to protein tyrosine phosphatase LAR. Mesenchymal stem cells or MSCs are originally name as bone marrow stromal cells. They are a population of adult stem cells with a large capacity for self-renewal and multipotency for differentiation into a variety of cell types including osteoblasts, chondrocytes, myocytes, adipocytes, β-pancreatic islets cells and certain neuronal cells. MSCs reside in many tissues, such as bone marrow, placenta, adipose tissue, adult peripheral blood, fetal blood, skin, as well as liver and lung. Besides their plasticity for tissue repair, MSCs also exhibit a powerful immunosuppressive activity and play important role in supporting hematopoiesis.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Retinoblastoma cell line (Weri-RB-1 cells)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2266513 (BioLegend Cat. No. 327606)

Antigen Details

Distribution

Mesenchymal stem cells, some neoplastic cell lines (HT29, Hela, MCF-7, REH)

Cell Type
Mesenchymal cells
Biology Area
Immunology
Antigen References

1. Buhring HJ, et al. 2007. Ann. N. Y. Acad. Sci. 1106:262.
2. Jackson L, et al. 2007 J. Postgrad. Med. 53:121.
3. Krampera M, et al. 2003 Blood 101:3722.
4. Ball LM, et al. 2007 Blood 110:2764

Gene ID
NA
UniProt
View information about MSC on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 2    Revision Date: 09.06.2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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