- SN2 (N6-D11) (See other available formats)
- Regulatory Status
- VI N-L099
- Other Names
- SN2, gp37, AD2
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
|Cat #||Size||Price||Quantity Check Availability||Save|
|329010||100 tests||242 CHF|
CD165 is a 37-42 kD transmembrane glycoprotein, also known as AD2, gp37, and SN2. It is expressed on immature thymocytes, most platelets, thymic epithelial cells, fibroblasts, and acute T-lymphoblastic leukemia (T-ALL) cells. CD165 has also been found to be expressed on monocytes and circulating T cells. In addition, CD165 has been detected on islet cells of the pancreas, Bowman's capsule of the kidney and on central nervous system neurons. SN2 antigen has been reported to be identical, or very similar, to the T-cell acute lymphoblastic leukemia antigen, TALLA-1. The biological function of CD165 is still not clear, though it has been proposed that CD165 plays a role in cell adhesion between thymocytes and thymic epithelial cells during development.Product Details
- Verified Reactivity
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Host Species
- purified human CD165 antigen from Molt-4 cell line
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunohistochemical staining of acetone-fixed frozen tissue sections.1, Western Blotting1, and immunofluorescence microscopy1
(PubMed link indicates BioLegend citation)
- Seon BK, et al. 1984. J. Immunol. 132:2089.
AB_2072596 (BioLegend Cat. No. 329010)
immature thymocytes, acute T-lymphoblastic leukemia (T-ALL) cells, epithelial cells, fibroblasts, platelets, monocytes and circulating T cells
- Cell Type
- Epithelial cells, Fibroblasts, Leukemia, Monocytes, Platelets, T cells, Thymocytes
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Kishimoto T, et al. 1997. ed. Leucocyte Typing VI:White Cell Differentiation Antigens. London:Garland Publishing.
2. Seon BK. 1995. Int. J. Cancer. 63:474.
3. Takagi S, et al. 1995. Int. J. Cancer. 61:706.
- Gene ID
- View information about CD165 on UniProt.org
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
|PE anti-human CD165||SN2 (N6-D11)||FC|
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