Purified anti-rat CD161 Recombinant Antibody

Pricing & Availability
Clone
QA19A15 (See other available formats)
Regulatory Status
RUO
Other Names
CD161, NKR-P1, CD161a/CD161b, NKR-P1a/KLRB1a
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA19A15_PURE_CD161_RECOM_Antibody_090921.png
Rat splenocytes were stained with purified anti-rat CD161 recombinant (clone QA19A15) (left) or purified mouse IgG1,κ isotype control (right) followed by goat anti-mouse IgG PE. Cells were costained for rat CD3 APC.
  • QA19A15_PURE_CD161_RECOM_Antibody_090921.png
    Rat splenocytes were stained with purified anti-rat CD161 recombinant (clone QA19A15) (left) or purified mouse IgG1,κ isotype control (right) followed by goat anti-mouse IgG PE. Cells were costained for rat CD3 APC.
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251102 100 µg $105.00
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Description

QA19A15 recombinant monoclonal antibody recognizes the rat killer cell lectin-like receptor subfamily B member1 protein, also known as CD161. CD161 is expressed on rat NK cells and T cell subpopulations, activated monocytes, and dendritic cells. CD161 molecules are C-type lectin-like receptors that can either activate (CD161a) or inhibit (CD161b) effector leucocyte responses, eg, cytotoxicity or cytokine production, against target cells which express C-type lectin-like related (Clr) molecules.

Product Details
Technical data sheet

Product Details

Reactivity
Rat
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2894684 (BioLegend Cat. No. 251102)

Antigen Details

Structure
CD161 is a 233 amino acid ~60 kDa homodimers, type II single pass protein containing a single C-type lectin domain.
Distribution

NK cells, subset of T cells, dendritic cells, activated monocytes.

Function
NKR-P1a is a NK cell-activating receptor; NKR-P1b is a NK cell-inhibitory receptor.
Ligand/Receptor
LLT1-ligand lectin like transcript 1; KLR-killer cell lectin like receptor.
Cell Type
Dendritic cells, Monocytes, NK cells, T cells
Biology Area
Cell Biology, Immunology, Innate Immunity, Signal Transduction
Molecular Family
CD Molecules
Antigen References
  1. Chambers WH, et al. 1989. J Exp Med. 169:1373.
  2. Brink M, et al. 1990. J Exp Med. 171:197.
  3. Li J, et al. 2003. Int Immunol. 15:411.
Gene ID
362443 View all products for this Gene ID
UniProt
View information about CD161 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 09/09/2021

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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