PE anti-human CD181 (CXCR1) Antibody

Pricing & Availability
8F1/CXCR1 (See other available formats)
Regulatory Status
Other Names
CD181, CXCR1, CDw128, CD128a, IL-8RA, Type I IL-8 receptor
Mouse IgG2b, κ
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Product Citations
Human peripheral blood granulocytes stained with 8F1 PE
  • 8F1slash-CXCR1-PE_111605
    Human peripheral blood granulocytes stained with 8F1 PE
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320608 100 tests $220.00
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CXCR1 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor A (IL-8RA), CD181, and CDw128a. It is a CXC chemokine receptor that belongs to the G protein-coupled receptor (CPCR) family. CXCR1 is expressed as homodimer or heterodimer with CXCR2 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. The expression level of CXCR1 on monocytes is lower than that of CXCR2. CXCR1 mediates neutrophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO-α(CXCL1).

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
Human CXCR1 transfected L1.2 cells
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: The 8F1/CXCR1 antibody is useful for immunofluorescent staining and flow cytometric analysis of CXCR1 expression.

Product Citations
  1. Brandau S, et al. 2011. J Leukoc Biol. 89:311. PubMed
  2. Shin M, et al. 2015. J Immunol. 195: 2861-2869. PubMed
  3. Silvin A, et al. 2020. Cell. 182:1401. PubMed
AB_439815 (BioLegend Cat. No. 320608)

Antigen Details

Seven transmembrane spanning, G protein-coupled receptor (CPCR), 67-70 kD, homodier or teterodimer with CXCR2

Granulocytes, NK cells, subset of T cells, monocytes, endothelial cells, oligodendrocytes

neutrophil activation, chemotaxis, angiogenesis
Cell Type
Granulocytes, NK cells, T cells, Monocytes, Endothelial cells, Oligodendrocytes, Neutrophils
Biology Area
Angiogenesis, Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Chuntharapai A, et al. 1994. J. Immunol. 153:5682.
2. Wilson S, et al. 2005. J. Biol. Chem. 280:28663.
3. Emadi S, et al. 2005. Blood 105:464.
4. Omari KM, et al. 2005. Brain 128:1003.
5. Juremalm M, G. Nilsson. 2005. Chem. Immunol. Allergy. 87:130.
6. Wolf M, et al. 1998. Eur. J. Immunol. 28:164

Gene ID
3577 View all products for this Gene ID
View information about CD181 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Does staining at room temperature or even at 37°C help for checking chemokine receptors expression?

Due to continuous recycling of many chemokine receptors, it may be worthwhile to consider staining at room temperature or at 37°C if the staining at lower temperature (which can potentially reduce receptor turnover) is not optimal.

Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • FITC anti-human CD181 (CXCR1)

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  • APC anti-human CD181 (CXCR1)

  • Alexa Fluor® 488 anti-human CD181 (CXCR1)

  • PE/Cyanine7 anti-human CD181 (CXCR1)

  • PerCP/Cyanine5.5 anti-human CD181 (CXCR1)

  • TotalSeq™-C1136 anti-human CD181 (CXCR1) Antibody

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