- SN13 (K5-1B8) (See other available formats)
- Regulatory Status
- Other Names
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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CD1b is a 43 kD member of the immunoglobulin superfamily also known as R1. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, CD1c), group II (CD1d), and group III (CD1e). CD1b plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1b has been implicated in thymic T cell development.Product Details
- Human, African Green, Cynomolgus
- Antibody Type
- Host Species
- Membrane antigen preparation of human thymocytes
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
Red Laser (633 nm)
(PubMed link indicates BioLegend citation)
- Hayes SM, et al. 2001. J. Immunol. 166:403. (IF)
- Martin LH, et al. 1987. P. Natl. Acad. Sci. USA 84:918993. (IF)
- Product Citations
AB_2563952 (BioLegend Cat. No. 329109)
AB_2563953 (BioLegend Cat. No. 329110)
- Immunoglobulin superfamily
- Cortical thymocytes, Langerhans cells, and dendritic cells
- Cell Type
- Thymocytes, Langerhans cells, Dendritic cells, Tregs
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Porcelli S, et al. 1992. Nature 360:5937.
2. Giuliani A, et al. 2001. Infect. Immun. 69:746170.
- Gene ID
- 910 View all products for this Gene ID
- View information about CD1b on UniProt.org
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