- 3T16 (See other available formats)
- Other Names
- Mouse IgG1, κ
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- Product Citations
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In vertebrate, Testosterone is the major male sex hormone that is essential to the development of reproductive organs and secondary sexual characteristics. It also plays a key role in muscle development, body mass increase and body fair growth. Importantly, it is critical to sperm development.
In vivo, testosterone is primarily secreted by testicles (in male), and by ovaries (in female), and eventually metabolized in liver. In the central nervous system, Testosterone is one of the key components of the hypothalamic-pituitary-adrenal axis, which is activated acutely by dominance challenger. It has been reported that different level of sex hormones, including testosterone, determines human behavior, as well as brain development and recovery after injury.Product Details
- Human, Mouse, Rat
- Antibody Type
- Host Species
- Testosterone-3-(O-carboxymethyl)oxime coupled to bovine serum albumin
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
ELISA Capture - Quality tested
Direct ELISA - Validated
- Recommended Usage
Each lot of this antibody is quality control tested by ELISA assay. For ELISA Capture applications, a concentration range of 10 - 150 ng/mL is recommended. For Direct ELISA applications, a concentration range of 1.0 - 10 ng/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody has been tested against human and mouse sera.
(PubMed link indicates BioLegend citation)
- Fantl VE, et al. 1983. J Steroid Biochem. 19(5):1605 (PubMed)
AB_2750291 (BioLegend Cat. No. 854001)
AB_2750292 (BioLegend Cat. No. 854002)
- Testosterone is an Androgen with a molecular mass of 288.431 g/mol.
Tissue Source: Primarily in reproductive organs (Testis, ovaries), trace amount in other organs including brain and liver.
Cellular Source: Secreted molecule.
- Ligand Receptor
- Binds to androgen receptors.
- Biology Area
- Cell Biology, Neuroscience, Synaptic Biology
- Antigen References
- Dong DX & Ji ZG. 2017. Chin Med J (Engl). 130:2991
- Roselli CE. 2017. J Neuroendocrinol. Doi:10.1111/jne.12562
- Mohammad OS, et al. 2017. Cancers (Basel). 9(12).pii:E166
- Gene ID
- View information about Testosterone on UniProt.org
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