Purified anti-human HLA-C Antibody

Pricing & Availability
Clone
DT-9 (See other available formats)
Other Names
HLAC, MHC Class I Antigen C
Isotype
Mouse IgG2b, κ
Ave. Rating
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Product Citations
publications
DT-9_PURE_HLA-C_Antibody_022317
Human peripheral blood lymphocytes were stained with purified HLA-C antibody (clone DT-9, filled histogram) or Mouse IgG2b, κ isotype control (open histogram), followed by goat anti-mouse IgG PE.
  • DT-9_PURE_HLA-C_Antibody_022317
    Human peripheral blood lymphocytes were stained with purified HLA-C antibody (clone DT-9, filled histogram) or Mouse IgG2b, κ isotype control (open histogram), followed by goat anti-mouse IgG PE.
Cat # Size Price Quantity Avail. Save
373302 100 µg $140
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Description

HLA-C belongs to the HLA class I heavy chain paralogues. MHC class I heavy chains associate with β2-microglobulin and are expressed on nearly all nucleated cells. MHC class I molecules are involved in the presentation of antigens to CD8+ T cells and thereby play an important role in cell-mediated immune responses and immune surveillance.

Product Details
Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified tamarin MHC class I molecules, corresponding to human HLA-C
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Corrah et al. 2011. J. Virol. 85: 3367.
  2. Apps et al. 2013. Science. 340:87.
  3. Braud et al. 1998. Curr. Biol. 8:1.
RRID
AB_2650941 (BioLegend Cat. No. 373302)

Antigen Details

Structure
Ig superfamily
Distribution

Nearly all cells

Function
Antigen peptide presentation
Ligand Receptor
TCR, CD8
Biology Area
Immunology
Molecular Family
MHC Antigens
Gene ID
3107 View all products for this Gene ID
UniProt
View information about HLA-C on UniProt.org

Related FAQs

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Go To Top Version: 0    Revision Date: 03/16/2017

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