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- Clone
- QA21A25 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- MHC-class I
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes cells were stained with purified anti-human HLA-A2 recombinant (clone QA21A25) (left), or purified mouse IgG1, κ isotype control (right), followed by goat-anti-mouse IgG PE. Cells were costained with anti-human CD3 APC.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 386702 | 100 µg | $190 | ||||
HLA-A2 is most common in Northern Asia and North America populations. MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells, playing an important role in cell-mediated immune responses and tumor surveillance.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Clone QA21A25 can completely block the binding of parental clone to target cells.
- RRID
-
AB_3068052 (BioLegend Cat. No. 386702)
Antigen Details
- Structure
- Ig superfamily
- Distribution
-
A*02 individuals’ leukocytes
- Function
- Antigen presentation
- Ligand/Receptor
- CD8, CD3/TCR
- Cell Type
- Leukocytes
- Biology Area
- Immunology
- Molecular Family
- MHC Antigens
- Antigen References
-
- Bjorkman PJ, et al. 2005. J Immunol. 174:6-19.
- Pandolfi F, et al. 1991. Cancer Res. 51:3164-70.
- Gene ID
- 3105 View all products for this Gene ID
- UniProt
- View information about HLA-A2 on UniProt.org
Related FAQs
Other Formats
View All HLA-A2 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human HLA-A2 Recombinant Antibody | QA21A25 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human HLA-A2 Recombinant Antibody
Human peripheral blood lymphocytes cells were stained with p...
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