- LN1 (See other available formats)
- Regulatory Status
- Other Names
- Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1), B cell antigen CD75
- Mouse IgM, κ
- Ave. Rating
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- Product Citations
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CD75 is a 43-85 kD type II transmembrane sialyltransferase protein, also known as beta-galactoside alpha-2,6-sialyltransferase. It is a member of glycosyltransferase family that transfers sialic acid from a donor substrate (CMP-sialic acid) to terminal galactose on glycan chains. CD75 is predominately expressed on germinal center originated B cells and lymphomas. It is also found on mature sIg+ B cells and epithelial cells of lung, breast, kidney, and prostate.
- Antibody Type
- Host Species
- Human PBL nuclei
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
IHC-P, IHC-F, WB - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining1,2 of frozen sections and formalin-fixed paraffin-embedded sections, and Western blotting3.
(PubMed link indicates BioLegend citation)
- Epstein AL, et al.1984. J. Immunol. 133:1028. (IHC)
- Marder RJ, et al. 1985. Lab. Invest. 52:497. (IHC)
- Kramer G, et al. 2004. BJU Int. 93:822. (WB)
- Product Citations
AB_2194435 (BioLegend Cat. No. 326901)
- 43-85 kD type II transmembrane sialoprotein, glycosyltransferase family
Germinal center derived B cells, epithelial cells
- Cell Type
- B cells, Epithelial cells
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Epstein AL, et al. 1984. J. Immunol. 133:1028.
2. Kramer G, et al. 2004. BJU Int. 93:822.
3. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication
- Gene ID
- 6480 View all products for this Gene ID
- View information about CD75 on UniProt.org
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