Purified anti-human CD210b (IL-10RB) Antibody

Pricing & Availability
S17009F (See other available formats)
Regulatory Status
Other Names
Interleukin 10 receptor subunit beta, CRFB4, CRF2-4, D21S58, D21S66, CDW210B
Mouse IgG2a, κ
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Product Citations
Human peripheral blood lymphocytes were stained CD210B (IL-10RB) (clone S17009F) Purified (left) or Mouse IgG2a, κ isotype control Purified (right), followed by anti-mouse IgG2a PE and HLA-DR PerCP.
  • S17009F_Purified_CD210b_Antibody_2_051419.png
    Human peripheral blood lymphocytes were stained CD210B (IL-10RB) (clone S17009F) Purified (left) or Mouse IgG2a, κ isotype control Purified (right), followed by anti-mouse IgG2a PE and HLA-DR PerCP.
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396802 100 µg $120.00
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CD210b is a Type 1 transmembrane glycoprotein also known as, subunit 2 (IL-10R2) and is an essential chain for the IL-10 receptor complex. The IL-10 receptor complex is made up of alpha (IL10-RA) and beta (IL-10RB) subunits. Coexpression of these subunits has been shown to be required for IL10 induced signal transduction. Binding of dimeric IL-10 to two alpha subunits can cause the recruitment of two beta subunits resulting in the transduction of the intracellular JAK/STAT pathway.

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
Human IL10RB-transfected cells
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

AB_2810606 (BioLegend Cat. No. 396802)

Antigen Details

Type 1 transmembrane glycoprotein belonging to the cytokine receptor family.

CD210b is expressed by a variety of cell types including T cells, B cells, NK cells, monocytes and macrophages.

Activates STAT1, STAT3, Jak1, Tyk and is a component of cytokine receptor complexes specific for IL-22, IL-26, IL-28, and IL-29.
Cell Type
B cells, Macrophages, NK cells, T cells, Thymocytes
Biology Area
Adaptive Immunity, Immunology, Signal Transduction
Molecular Family
Cytokine/Chemokine Receptors
Antigen References
  1. Donnelly RP, et al. 2004. J Leukoc Biol. 76(2):314-321.  
  2. Koppelman B, et al. 1997. Immunity. (6): 861-871
  3. Kotenko SV, et al. 1997. EMBO J. 16(19):5894-5903. 
  4. Liu Y, et al. 1995. J Immunol. 152(4):1821-1829.
Gene ID
3588 View all products for this Gene ID
View information about CD210b on UniProt.org

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Go To Top Version: 1    Revision Date: 05/14/2019

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