Purified anti-GABRA1 Antibody (Previously Covance catalog# MMS-5132)

Pricing & Availability
Clone
N95/35 (See other available formats)
Other Names
GABA(A)R, α1, Gamma-aminobutyric acid receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABA(A) receptor subunit alpha-1
Previously
Covance Catalog# MMS-5132
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
N95slash35_Purified_GABRA1_Antibody_WB_010919_updated.png
Western blot of purified anti-GABRA1 antibody (clone N95/35). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain nuclear lysate; Lane 3: 20 µg of mouse brain nuclear lysate; Lane 4: 20 µg of rat brain nuclear lysate. The blot was incubated with 0.1 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
  • N95slash35_Purified_GABRA1_Antibody_WB_010919_updated.png
    Western blot of purified anti-GABRA1 antibody (clone N95/35). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain nuclear lysate; Lane 3: 20 µg of mouse brain nuclear lysate; Lane 4: 20 µg of rat brain nuclear lysate. The blot was incubated with 0.1 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
Cat # Size Price Quantity Avail. Save
832301 100 µl $140
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Description

Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1) is a component of the hetero-pentameric receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. The receptor is a ligand-gated multi-subunit chloride channel. Mutations in the GABRA1 gene have been associated with juvenile myoclonic epilepsy and childhood absence epilepsy type 4.

Product Details
Technical data sheet

Product Details

Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This monoclonal antibody was raised against a fusion protein corresponding to amino acids 355-394 (cytoplasmic loop) of human GABA(A)R, Alpha1.
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 10 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2564955 (BioLegend Cat. No. 832301)

Antigen Details

Structure
Expected MW: 52 kD
Cell Type
GABAergic Neurons
Biology Area
Cell Biology, Neuroscience, Neuroscience Cell Markers, Synaptic Biology
Molecular Family
Postsynaptic proteins
Gene ID
2554 View all products for this Gene ID
UniProt
View information about GABRA1 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 3    Revision Date: 01/09/2019

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