- 536 (See other available formats)
- Other Names
- Vγ3 T-cell receptor, T cell receptor gamma 3
- Syrian hamster IgG
- Ave. Rating
- 1 reviews
- Product Citations
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Vγ3+ T cells are the predominant γδ TCR-bearing cells in early fetal thymus. The majority of CD3+ cells in 14-day fetal thymus express Vγ3. Vγ3 is also expressed on Thy-1+ dendritic epidermal cells (Thy-1+ DECs). Cells that express Vγ3 are not significantly detectable in adult lymphoid organs. It has been reported that Lck and Fyn, two Src family kinases, are required for the development of Vγ3+ T cells.Product Details
- Antibody Type
- Host Species
- Syrian Hamster
- AKR mouse dendritic epidermal cell clone 7-17
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported (for relevant formats) application include: immunoprecipitation1 and immunofluorescence2.
This product may be used for research purposes only. It is not licensed for resale and may only be used by the buyer. This product may not be used and is not licensed for clinical assays, where the results of such assays are provided as a diagnostic service. If a diagnostic or therapeutic use is anticipated, then a license must be requested from the University of California. This availability of such diagnostic and therapeutic use license(s) cannot be guaranteed from the University of California.
(PubMed link indicates BioLegend citation)
- Product Citations
AB_10551420 (BioLegend Cat. No. 137503)
AB_10550807 (BioLegend Cat. No. 137504)
- A member of Ig superfamily, heterodimerized with δ TCR chain and associated with CD3 complex.
Dendritic epidermal T cells (DECs) and fetal murine thymocytes.
- Antigen recognition
- Ligand Receptor
- Cell Type
- T cells, Thymocytes
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- Antigen References
1. Allison JP, et al. 1991. Annu. Rev. Immunol. 9:679.
2. O’Brien RL, et al. 2000. J. Immunol. 165:6472.
3. Kelly KA, et al. 1993. Int Immunol. 5:331.
4. Moore TA, et al. 1996. J. Immunol. 157:2366.
5. Payer E, et al. 1991. J. Immunol. 146:2536.
6. Van Oers NSC, et al. 1996. Immunity 5:429.
- Gene ID
- 110067 View all products for this Gene ID
- View information about TCR V gamma 3 on UniProt.org
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
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