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PE anti-human FPR3 (FPRL2) Antibody

Pricing & Availability
Clone
K102B9 (See other available formats)
Regulatory Status
RUO
Other Names
FMLPY, FPRH2, formyl peptide receptor like 2, FPR3, formyl peptide receptor 3
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
K102B9_PE_FPRL2_Antibody_FC_1_040113
FPRL2 transfected CHO cells (top) or human peripheral blood monocytes (bottom) were stained with FPRL2 (clone K102B9) PE (filled histograms) or mouse IgG2a, κ PE isotype control (open histograms).
  • K102B9_PE_FPRL2_Antibody_FC_1_040113
    FPRL2 transfected CHO cells (top) or human peripheral blood monocytes (bottom) were stained with FPRL2 (clone K102B9) PE (filled histograms) or mouse IgG2a, κ PE isotype control (open histograms).
  • K102B9_PE_FPRL2_Antibody_FC_2_040113
See PE spectral data
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357703 25 tests $153
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357704 100 tests $360
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Description

FPR3, also known as FPRL2, belongs to the formyl peptide receptor family which includes FPR1, FPR2, and FPR3.  Monocytes express FPR1, 2, and 3; upon differentiation into macrophages, expression of these receptors is maintained. Two ligands, humanin and F2L have been identified.  Humanin is expressed in the heart, skeletal muscle, kidney, and liver but is not expressed in the immune system.  F2L is a heme-binding protein first identified in the spleen.  Binding of FPRL2 and F2L induces Ca2+ mobilization and neutrophil chemotaxis.  Low level of expression of FPRL2 has also been reported on NK cells.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
DNA vaccine containing full length FPRL2.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2561983 (BioLegend Cat. No. 357703)
AB_2561984 (BioLegend Cat. No. 357704)

Antigen Details

Structure
40 kD, seven transmembrane protein
Distribution
Monocytes, macrophages, basophils, plasmacytoid dendritic cells
Function
Neutrophil chemotaxis and degranulation
Ligand/Receptor
Humanin and FPRL2 ligand (F2L)
Cell Type
Monocytes, Macrophages, Basophils, Dendritic cells
Biology Area
Immunology, Innate Immunity
Antigen References

1. Devosse T, et al. 2009. J. Immunol. 182:4974.
2. Yang D, et al. 2002. J. Leukoc. Biol. 72:598.
3. Harada M, et al. 2004. Biochem. Biophys. Res. Commun. 324:255.
4. Migeotte I, et al. 2005. J. Exp. Med. 201:83.
5. Gao JL, et al. 2007. J. Immunol. 178:1450.

Gene ID
2359 View all products for this Gene ID
UniProt
View information about FPR3 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 04/05/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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