Purified anti-human CXCR7 Antibody

Pricing & Availability
10D1-J16 (See other available formats)
Regulatory Status
Other Names
Chemokine (C-X-C motif) receptor 7, RDC1, CMKOR1, GPR159, ACKR3
Mouse IgG2a, κ
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Product Citations
CXCR7-transfected L1.2 cells were stained with purified CXCR7 (clone 10D1-J16) (filled histogram) or purified mouse IgG2a, κ isotype control (open histogram), followed by anti-mouse IgG PE.
  • 10D1-J16_PURE_CXCR7_Antibody_FC_042315
    CXCR7-transfected L1.2 cells were stained with purified CXCR7 (clone 10D1-J16) (filled histogram) or purified mouse IgG2a, κ isotype control (open histogram), followed by anti-mouse IgG PE.
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391402 100 µg 212€
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CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with a high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. The binding of a ligand to CXCR7 induces proliferation and migration of immature neurons, glia, and their precursors. CXCR7 expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells, and mature dendritic cells. Surface expression of CXCR7 has been also reported in tumor cells, activated endothelial cells, and fetal liver cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

AB_2565219 (BioLegend Cat. No. 391402)

Antigen Details

G Protein-Coupled Receptor super family
Monocytes, B cells, T cells, and mature dendritic cells.
Regulates trafficking and activation of leukocytes.
CXCL12/SDF-1 and CXCL11/I-TAC.
Cell Type
Monocytes, B cells, T cells, Dendritic cells
Biology Area
Cell Biology, Immunology, Signal Transduction
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Torossian F, et al. 2014. Blood 123:191.
2. Walentowicz-Sadlecka M, et al. 2014. PLoS One 1:e84629.
3. Yates TJ, et al. 2013. Cancer 119:61.
4. Burns JM, et al. 2006. J. Exp. Med. 203:2201.
5. Infantino S, et al. 2006. J. Immunol. 176:2197.

Gene ID
57007 View all products for this Gene ID
View information about CXCR7 on UniProt.org

Related FAQs

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Go To Top Version: 1    Revision Date: 04.23.2015

For Research Use Only. Not for diagnostic or therapeutic use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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